Motif ID: Cbfb

Z-value: 0.353


Transcription factors associated with Cbfb:

Gene SymbolEntrez IDGene Name
Cbfb ENSMUSG00000031885.7 Cbfb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cbfbmm10_v2_chr8_+_105170668_1051706860.174.0e-01Click!


Activity profile for motif Cbfb.

activity profile for motif Cbfb


Sorted Z-values histogram for motif Cbfb

Sorted Z-values for motif Cbfb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cbfb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 1.345 ENSMUST00000168589.1
Sla
src-like adaptor
chr14_+_101729907 1.341 ENSMUST00000100337.3
Lmo7
LIM domain only 7
chr11_-_83649349 1.156 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr5_+_104435112 0.597 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
Spp1





secreted phosphoprotein 1





chr14_-_101729690 0.500 ENSMUST00000066461.3
Gm9922
predicted gene 9922
chr19_-_50678642 0.468 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr19_-_50678485 0.377 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr2_+_164948219 0.341 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr2_+_172393794 0.321 ENSMUST00000099061.2
ENSMUST00000103073.2
Cass4

Cas scaffolding protein family member 4

chr7_-_90129339 0.238 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr4_-_6990774 0.229 ENSMUST00000039987.3
Tox
thymocyte selection-associated high mobility group box
chr2_+_32721055 0.221 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr8_+_3353415 0.202 ENSMUST00000098966.3
A430078G23Rik
RIKEN cDNA A430078G23 gene
chr12_+_95692212 0.167 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr10_+_69925954 0.158 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr17_-_64331817 0.154 ENSMUST00000172733.1
ENSMUST00000172818.1
Pja2

praja 2, RING-H2 motif containing

chr1_+_151755339 0.146 ENSMUST00000059498.5
Edem3
ER degradation enhancer, mannosidase alpha-like 3
chr15_+_99393219 0.143 ENSMUST00000159209.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr5_+_24364804 0.122 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr11_-_17008647 0.114 ENSMUST00000102881.3
Plek
pleckstrin
chr15_+_99392948 0.107 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr6_+_136954521 0.104 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr8_+_90828820 0.071 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr7_-_46795661 0.068 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr7_-_46795881 0.054 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr15_+_99393574 0.041 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr11_-_74724670 0.031 ENSMUST00000021091.8
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr15_+_99393610 0.021 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr1_+_63176818 0.007 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122)
0.1 0.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.6 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0 0.1 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.1 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.3 GO:0042805 actinin binding(GO:0042805)
0.0 1.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)