Motif ID: Cebpa_Cebpg

Z-value: 0.985

Transcription factors associated with Cebpa_Cebpg:

Gene SymbolEntrez IDGene Name
Cebpa ENSMUSG00000034957.9 Cebpa
Cebpg ENSMUSG00000056216.8 Cebpg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpamm10_v2_chr7_+_35119285_351193010.554.0e-03Click!
Cebpgmm10_v2_chr7_-_35056467_35056556-0.252.2e-01Click!


Activity profile for motif Cebpa_Cebpg.

activity profile for motif Cebpa_Cebpg


Sorted Z-values histogram for motif Cebpa_Cebpg

Sorted Z-values for motif Cebpa_Cebpg



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Top targets:


Showing 1 to 20 of 164 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103813913 4.865 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr6_+_17463749 4.071 ENSMUST00000115443.1
 Met
met proto-oncogene
chr14_+_65970610 3.479 ENSMUST00000127387.1
 Clu
clusterin
chr14_+_65971049 3.287 ENSMUST00000128539.1
 Clu
clusterin
chr9_+_37367354 3.121 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr2_-_129371131 3.106 ENSMUST00000028881.7
 Il1b
interleukin 1 beta
chr3_+_19957037 2.990 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
 Cp


ceruloplasmin


chr3_+_66219909 2.909 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr14_+_65971164 2.569 ENSMUST00000144619.1
 Clu
clusterin
chr9_-_121495678 2.410 ENSMUST00000035120.4
 Cck
cholecystokinin
chr14_+_65970804 2.269 ENSMUST00000138191.1
 Clu
clusterin
chr19_-_57239310 1.889 ENSMUST00000111559.1
 Ablim1
actin-binding LIM protein 1
chr10_-_102490418 1.888 ENSMUST00000020040.3
 Nts
neurotensin
chr2_+_102706356 1.846 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
 Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr1_-_22315792 1.709 ENSMUST00000164877.1
 Rims1
regulating synaptic membrane exocytosis 1
chrX_-_162565514 1.546 ENSMUST00000154424.1
 Reps2
RALBP1 associated Eps domain containing protein 2
chr1_+_169655493 1.489 ENSMUST00000027997.3
 Rgs5
regulator of G-protein signaling 5
chr16_+_42907563 1.434 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr14_+_51091077 1.360 ENSMUST00000022428.5
ENSMUST00000171688.1
 Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr12_+_74297474 1.351 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 11.6 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.5 4.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.0 3.1 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.2 3.0 GO:0046688 response to copper ion(GO:0046688)
1.0 2.9 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 2.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.4 2.0 GO:0046684 response to pyrethroid(GO:0046684)
0.0 1.9 GO:0008542 visual learning(GO:0008542)
0.3 1.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 1.7 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 1.6 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 1.6 GO:0007050 cell cycle arrest(GO:0007050)
0.5 1.4 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.2 1.4 GO:0032264 IMP salvage(GO:0032264)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.3 GO:0071398 cellular response to fatty acid(GO:0071398)
0.3 1.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 1.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 1.1 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 1.0 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 11.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 5.4 GO:0009925 basal plasma membrane(GO:0009925)
1.2 4.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 3.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 2.4 GO:0043203 axon hillock(GO:0043203)
0.0 2.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.1 GO:0030141 secretory granule(GO:0030141)
0.1 2.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.9 GO:0043679 axon terminus(GO:0043679)
0.1 1.8 GO:0030673 axolemma(GO:0030673)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.5 1.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 1.3 GO:0030054 cell junction(GO:0030054)
0.1 1.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 11.6 GO:0051787 misfolded protein binding(GO:0051787)
1.2 4.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.2 4.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.0 4.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 3.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.6 3.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 2.9 GO:0001849 complement component C1q binding(GO:0001849)
0.0 2.3 GO:0044325 ion channel binding(GO:0044325)
0.1 2.0 GO:0031402 sodium ion binding(GO:0031402)
0.5 1.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.3 GO:0005507 copper ion binding(GO:0005507)
0.2 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.3 1.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.2 1.0 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.1 1.0 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)