Motif ID: Creb1

Z-value: 2.245


Transcription factors associated with Creb1:

Gene SymbolEntrez IDGene Name
Creb1 ENSMUSG00000025958.8 Creb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_645328150.331.0e-01Click!


Activity profile for motif Creb1.

activity profile for motif Creb1


Sorted Z-values histogram for motif Creb1

Sorted Z-values for motif Creb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_6084983 7.285 ENSMUST00000025704.2
Cdca5
cell division cycle associated 5
chr10_+_121033960 6.992 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr7_-_38107490 6.982 ENSMUST00000108023.3
Ccne1
cyclin E1
chr13_-_29984219 6.838 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr15_-_76710486 6.809 ENSMUST00000036852.7
Recql4
RecQ protein-like 4
chr7_-_137314394 6.496 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr12_-_56535047 6.419 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr9_+_122951051 5.076 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr10_-_30200492 4.938 ENSMUST00000099985.4
Cenpw
centromere protein W
chr11_+_43528759 4.732 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr5_+_150522599 4.571 ENSMUST00000044620.7
Brca2
breast cancer 2
chr3_+_135212557 4.293 ENSMUST00000062893.7
Cenpe
centromere protein E
chr6_+_113531675 4.237 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr5_-_65335597 4.234 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
Rfc1


replication factor C (activator 1) 1


chr2_+_156840966 4.218 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr10_+_127041931 4.198 ENSMUST00000006915.7
ENSMUST00000120542.1
Mettl1

methyltransferase like 1

chr5_-_65335564 4.133 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr2_+_119047116 4.022 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr10_-_7792795 4.013 ENSMUST00000065124.1
6530403G13Rik
RIKEN cDNA 6530403G13 gene
chr6_-_112696604 3.979 ENSMUST00000113182.1
ENSMUST00000113180.1
ENSMUST00000068487.5
ENSMUST00000077088.4
Rad18



RAD18 homolog (S. cerevisiae)




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 154 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 11.6 GO:0030488 tRNA methylation(GO:0030488)
0.3 11.2 GO:0006270 DNA replication initiation(GO:0006270)
2.3 9.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 9.3 GO:0006364 rRNA processing(GO:0006364)
0.5 7.4 GO:0034501 protein localization to kinetochore(GO:0034501)
2.4 7.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 7.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
2.3 6.9 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
1.4 6.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.1 6.8 GO:0045875 DNA strand renaturation(GO:0000733) negative regulation of sister chromatid cohesion(GO:0045875)
0.6 6.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
2.1 6.4 GO:0021759 globus pallidus development(GO:0021759)
0.9 6.3 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.4 5.8 GO:0015693 magnesium ion transport(GO:0015693)
0.1 5.3 GO:0051297 centrosome organization(GO:0051297)
0.3 5.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 5.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 5.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.5 5.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.5 5.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 104 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 24.5 GO:0005730 nucleolus(GO:0005730)
0.1 15.4 GO:0000776 kinetochore(GO:0000776)
0.2 13.0 GO:0005871 kinesin complex(GO:0005871)
0.0 12.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 11.2 GO:0005694 chromosome(GO:0005694)
0.1 9.3 GO:0030139 endocytic vesicle(GO:0030139)
0.1 8.5 GO:0005643 nuclear pore(GO:0005643)
1.4 8.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 8.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.8 7.3 GO:0008278 cohesin complex(GO:0008278)
1.4 6.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 6.9 GO:0000793 condensed chromosome(GO:0000793)
0.6 6.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 5.6 GO:0035869 ciliary transition zone(GO:0035869)
0.1 5.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 5.5 GO:0005811 lipid particle(GO:0005811)
0.5 5.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.3 5.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 4.8 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.4 4.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 21.4 GO:0044822 poly(A) RNA binding(GO:0044822)
0.2 13.0 GO:0003777 microtubule motor activity(GO:0003777)
0.2 12.6 GO:0000049 tRNA binding(GO:0000049)
1.5 9.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 8.5 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.8 8.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 7.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 7.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.6 7.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 7.0 GO:0017147 Wnt-protein binding(GO:0017147)
1.4 6.8 GO:0000405 bubble DNA binding(GO:0000405)
0.0 6.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 5.5 GO:0001047 core promoter binding(GO:0001047)
0.0 5.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.4 5.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 4.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
1.5 4.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 4.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 4.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 4.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)