Motif ID: Creb3l2

Z-value: 0.739


Transcription factors associated with Creb3l2:

Gene SymbolEntrez IDGene Name
Creb3l2 ENSMUSG00000038648.5 Creb3l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l2mm10_v2_chr6_-_37442095_374421540.096.8e-01Click!


Activity profile for motif Creb3l2.

activity profile for motif Creb3l2


Sorted Z-values histogram for motif Creb3l2

Sorted Z-values for motif Creb3l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3l2

PNG image of the network

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Top targets:


Showing 1 to 20 of 140 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_50841434 3.697 ENSMUST00000114887.2
 2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr9_-_43239816 3.334 ENSMUST00000034512.5
 Oaf
OAF homolog (Drosophila)
chr2_-_92370999 3.217 ENSMUST00000176810.1
ENSMUST00000090582.4
 Gyltl1b

glycosyltransferase-like 1B

chr2_+_84840612 3.071 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1
chr10_+_20148920 2.725 ENSMUST00000116259.3
 Map7
microtubule-associated protein 7
chr10_+_13090788 2.709 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
 Plagl1


pleiomorphic adenoma gene-like 1


chr11_-_94653964 2.653 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr2_-_92371039 2.455 ENSMUST00000068586.6
 Gyltl1b
glycosyltransferase-like 1B
chr2_-_105399286 2.345 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr7_+_19094594 2.218 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr10_+_20148457 2.179 ENSMUST00000020173.8
 Map7
microtubule-associated protein 7
chr19_+_34922351 2.110 ENSMUST00000087341.5
 Kif20b
kinesin family member 20B
chr15_+_34238026 2.093 ENSMUST00000022867.3
 Laptm4b
lysosomal-associated protein transmembrane 4B
chr2_-_92370968 2.076 ENSMUST00000176774.1
 Gyltl1b
glycosyltransferase-like 1B
chr16_-_78376758 2.006 ENSMUST00000023570.7
 Btg3
B cell translocation gene 3
chr7_+_79392305 1.990 ENSMUST00000117227.1
ENSMUST00000118959.1
ENSMUST00000036865.6
 Fanci


Fanconi anemia, complementation group I


chr5_-_30945393 1.671 ENSMUST00000031051.6
 Cgref1
cell growth regulator with EF hand domain 1
chr15_-_34495180 1.596 ENSMUST00000022946.5
 Hrsp12
heat-responsive protein 12
chr13_-_119408985 1.503 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
 Nnt


nicotinamide nucleotide transhydrogenase


chr6_-_83317589 1.493 ENSMUST00000005810.6
 Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.3 4.9 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 3.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.5 2.7 GO:0072429 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 2.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.6 2.6 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 2.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 2.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.2 2.2 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.4 2.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.1 2.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.0 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.1 1.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 1.6 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.3 1.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 1.5 GO:0006739 NADP metabolic process(GO:0006739)
0.5 1.4 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 1.4 GO:0000154 rRNA modification(GO:0000154)
0.0 1.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3 1.3 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 2.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.2 2.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 2.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.3 GO:0043196 varicosity(GO:0043196)
0.2 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 1.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.3 1.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.7 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.1 0.5 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 7.7 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.1 3.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 2.7 GO:0004519 endonuclease activity(GO:0004519)
0.6 2.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 2.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.5 1.5 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 1.5 GO:0050661 NADP binding(GO:0050661)
0.1 1.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.4 GO:0005536 glucose binding(GO:0005536)
0.0 1.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.4 GO:0019894 kinesin binding(GO:0019894)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.3 GO:0017022 myosin binding(GO:0017022)
0.4 1.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.4 1.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)