Motif ID: Crem_Jdp2

Z-value: 0.374

Transcription factors associated with Crem_Jdp2:

Gene SymbolEntrez IDGene Name
Crem ENSMUSG00000063889.10 Crem
Jdp2 ENSMUSG00000034271.9 Jdp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cremmm10_v2_chr18_-_3281036_3281132-0.442.3e-02Click!
Jdp2mm10_v2_chr12_+_85599388_855994160.019.5e-01Click!


Activity profile for motif Crem_Jdp2.

activity profile for motif Crem_Jdp2


Sorted Z-values histogram for motif Crem_Jdp2

Sorted Z-values for motif Crem_Jdp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Crem_Jdp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_12321899 1.420 ENSMUST00000180521.1
 1810049J17Rik
RIKEN cDNA 1810049J17 gene
chr3_+_129199919 1.247 ENSMUST00000029657.9
ENSMUST00000106382.4
 Pitx2

paired-like homeodomain transcription factor 2

chr11_-_84525514 1.053 ENSMUST00000018842.7
 Lhx1
LIM homeobox protein 1
chr6_-_23248264 1.023 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr3_+_129199878 0.982 ENSMUST00000174661.2
 Pitx2
paired-like homeodomain transcription factor 2
chr11_+_84525669 0.961 ENSMUST00000126072.1
ENSMUST00000128121.1
 1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr15_+_34238026 0.920 ENSMUST00000022867.3
 Laptm4b
lysosomal-associated protein transmembrane 4B
chr13_+_23531044 0.867 ENSMUST00000102972.3
 Hist1h4h
histone cluster 1, H4h
chr11_+_84525647 0.842 ENSMUST00000134800.1
 1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr1_-_134079114 0.838 ENSMUST00000020692.6
 Btg2
B cell translocation gene 2, anti-proliferative
chr17_+_43952999 0.817 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr4_+_141301228 0.815 ENSMUST00000006614.2
 Epha2
Eph receptor A2
chr1_+_71652837 0.795 ENSMUST00000097699.2
 Apol7d
apolipoprotein L 7d
chr11_+_101468164 0.795 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr3_+_135212557 0.783 ENSMUST00000062893.7
 Cenpe
centromere protein E
chr5_-_106458440 0.755 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr9_+_102718424 0.751 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
 Amotl2


angiomotin-like 2


chr17_+_43953191 0.745 ENSMUST00000044792.4
 Rcan2
regulator of calcineurin 2
chr7_-_142899985 0.679 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr2_+_105668888 0.676 ENSMUST00000111086.4
ENSMUST00000111087.3
 Pax6

paired box gene 6


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.3 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1 1.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 1.3 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 1.2 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.4 1.1 GO:0060067 cervix development(GO:0060067) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.2 1.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 1.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.0 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.9 GO:0060013 righting reflex(GO:0060013)
0.3 0.8 GO:0014028 notochord formation(GO:0014028)
0.2 0.8 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.8 GO:0035329 hippo signaling(GO:0035329)
0.2 0.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.6 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.1 0.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.6 GO:0072520 seminiferous tubule development(GO:0072520)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 0.8 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.1 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 0.4 GO:1990423 RZZ complex(GO:1990423)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0001940 male pronucleus(GO:0001940)
0.1 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.1 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0030018 Z disc(GO:0030018) I band(GO:0031674)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 1.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.7 GO:0035240 dopamine binding(GO:0035240)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 0.6 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)