Motif ID: Crx_Gsc

Z-value: 0.439

Transcription factors associated with Crx_Gsc:

Gene SymbolEntrez IDGene Name
Crx ENSMUSG00000041578.9 Crx
Gsc ENSMUSG00000021095.4 Gsc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Crxmm10_v2_chr7_-_15879844_158799680.154.7e-01Click!


Activity profile for motif Crx_Gsc.

activity profile for motif Crx_Gsc


Sorted Z-values histogram for motif Crx_Gsc

Sorted Z-values for motif Crx_Gsc



Network of associatons between targets according to the STRING database.



First level regulatory network of Crx_Gsc

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_65968483 2.799 ENSMUST00000022616.6
 Clu
clusterin
chr11_+_104231390 1.696 ENSMUST00000106992.3
 Mapt
microtubule-associated protein tau
chr9_-_53975246 1.497 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chrX_+_7919816 1.174 ENSMUST00000041096.3
 Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_-_164404606 1.157 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
 Matn4


matrilin 4


chr4_+_74013442 1.153 ENSMUST00000098006.2
ENSMUST00000084474.5
 Frmd3

FERM domain containing 3

chrX_+_73483602 1.067 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr10_+_90576872 0.973 ENSMUST00000182550.1
ENSMUST00000099364.5
 Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr7_+_44384098 0.850 ENSMUST00000118962.1
ENSMUST00000118831.1
 Syt3

synaptotagmin III

chr7_+_44384803 0.829 ENSMUST00000120262.1
 Syt3
synaptotagmin III
chr6_-_59426279 0.806 ENSMUST00000051065.4
 Gprin3
GPRIN family member 3
chr7_+_44384604 0.802 ENSMUST00000130707.1
ENSMUST00000130844.1
 Syt3

synaptotagmin III

chr13_+_49608030 0.789 ENSMUST00000021822.5
 Ogn
osteoglycin
chr7_+_99535439 0.779 ENSMUST00000098266.2
ENSMUST00000179755.1
 Arrb1

arrestin, beta 1

chr17_-_25570678 0.760 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr5_-_142608785 0.722 ENSMUST00000037048.7
 Mmd2
monocyte to macrophage differentiation-associated 2
chrX_-_139714481 0.694 ENSMUST00000183728.1
 Gm15013
predicted gene 15013
chr8_-_54724317 0.688 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
 Wdr17


WD repeat domain 17


chr11_+_101246405 0.683 ENSMUST00000122006.1
ENSMUST00000151830.1
 Ramp2

receptor (calcitonin) activity modifying protein 2

chr19_+_26605106 0.663 ENSMUST00000025862.7
ENSMUST00000176030.1
 Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.1 2.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 1.7 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.2 1.4 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 1.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 1.2 GO:0002021 response to dietary excess(GO:0002021)
0.1 1.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.9 GO:0048678 response to axon injury(GO:0048678)
0.3 0.8 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.1 0.6 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.6 GO:1990743 protein sialylation(GO:1990743)
0.1 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.8 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 2.3 GO:0070382 exocytic vesicle(GO:0070382)
0.2 1.7 GO:0045298 tubulin complex(GO:0045298)
0.1 1.4 GO:0031143 pseudopodium(GO:0031143)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 2.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.5 1.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.1 0.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0032051 clathrin light chain binding(GO:0032051)