Motif ID: Cxxc1

Z-value: 0.236


Transcription factors associated with Cxxc1:

Gene SymbolEntrez IDGene Name
Cxxc1 ENSMUSG00000024560.6 Cxxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cxxc1mm10_v2_chr18_+_74216118_742161450.058.2e-01Click!


Activity profile for motif Cxxc1.

activity profile for motif Cxxc1


Sorted Z-values histogram for motif Cxxc1

Sorted Z-values for motif Cxxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cxxc1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_49636847 1.036 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr8_+_92357787 0.991 ENSMUST00000034184.10
Irx5
Iroquois related homeobox 5 (Drosophila)
chr10_+_50895651 0.738 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr12_+_110279228 0.572 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr11_-_68386974 0.568 ENSMUST00000135141.1
Ntn1
netrin 1
chr5_-_4758216 0.315 ENSMUST00000054294.4
Fzd1
frizzled homolog 1 (Drosophila)
chrX_+_53607987 0.231 ENSMUST00000063384.3
ENSMUST00000169626.1
Cxx1c

CAAX box 1C

chrX_+_53607918 0.195 ENSMUST00000114827.1
Cxx1c
CAAX box 1C
chr8_+_70594466 0.191 ENSMUST00000019283.9
Isyna1
myo-inositol 1-phosphate synthase A1
chr10_-_79874565 0.155 ENSMUST00000167250.1
ENSMUST00000092325.4
BC005764

cDNA sequence BC005764

chr5_-_125389177 0.142 ENSMUST00000108707.2
Ubc
ubiquitin C
chr5_+_125389284 0.142 ENSMUST00000100700.2
Gm10382
predicted gene 10382
chr11_+_97415527 0.134 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr15_+_74516196 0.116 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr3_-_101307079 0.107 ENSMUST00000097146.2
Gm10355
predicted gene 10355
chr15_-_77153772 0.100 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr10_+_128058974 0.096 ENSMUST00000084771.2
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr11_+_80383279 0.086 ENSMUST00000165565.1
ENSMUST00000017567.7
Zfp207

zinc finger protein 207

chr12_-_82496537 0.080 ENSMUST00000179295.1
Gm5435
predicted gene 5435
chr5_-_125389915 0.079 ENSMUST00000136312.1
Ubc
ubiquitin C
chr9_-_106789130 0.077 ENSMUST00000046502.5
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr10_+_128058947 0.071 ENSMUST00000052798.7
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr5_-_65391380 0.067 ENSMUST00000120094.1
ENSMUST00000118543.1
ENSMUST00000127874.1
Rpl9


ribosomal protein L9


chr11_-_89302545 0.067 ENSMUST00000061728.3
Nog
noggin
chr5_-_65391408 0.063 ENSMUST00000057885.6
Rpl9
ribosomal protein L9
chr11_-_69920581 0.057 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr3_-_89960562 0.051 ENSMUST00000069805.7
Atp8b2
ATPase, class I, type 8B, member 2
chr9_+_78109188 0.049 ENSMUST00000118869.1
ENSMUST00000125615.1
Ick

intestinal cell kinase

chr7_+_128744870 0.046 ENSMUST00000042942.8
Sec23ip
Sec23 interacting protein
chr5_+_65391497 0.045 ENSMUST00000031101.3
ENSMUST00000122026.1
Lias

lipoic acid synthetase

chr10_-_7681118 0.044 ENSMUST00000159977.1
ENSMUST00000162682.1
Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr1_-_180813534 0.044 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chrX_+_48623737 0.042 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr11_-_69920892 0.040 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr11_+_32205411 0.036 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr10_-_79766872 0.035 ENSMUST00000047203.8
Rnf126
ring finger protein 126
chr17_-_14203695 0.033 ENSMUST00000053218.5
Dact2
dapper homolog 2, antagonist of beta-catenin (xenopus)
chr11_+_32205483 0.032 ENSMUST00000121182.1
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chrX_-_7375830 0.026 ENSMUST00000115744.1
Usp27x
ubiquitin specific peptidase 27, X chromosome
chr9_-_78108587 0.023 ENSMUST00000162625.1
ENSMUST00000159099.1
Fbxo9

f-box protein 9

chr11_-_69921057 0.018 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr15_+_82147238 0.015 ENSMUST00000023100.6
Srebf2
sterol regulatory element binding factor 2
chr10_+_80249441 0.015 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr5_+_115565254 0.014 ENSMUST00000064454.7
Gcn1l1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr11_+_60537978 0.009 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr8_-_111393810 0.006 ENSMUST00000038475.8
Fa2h
fatty acid 2-hydroxylase
chr8_-_120589304 0.005 ENSMUST00000034278.5
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr4_+_109000770 0.001 ENSMUST00000106644.2
Nrd1
nardilysin, N-arginine dibasic convertase, NRD convertase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.6 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 1.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990047 spindle matrix(GO:1990047)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)