Motif ID: Ddit3

Z-value: 0.904


Transcription factors associated with Ddit3:

Gene SymbolEntrez IDGene Name
Ddit3 ENSMUSG00000025408.9 Ddit3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ddit3mm10_v2_chr10_+_127290774_127290803-0.058.1e-01Click!


Activity profile for motif Ddit3.

activity profile for motif Ddit3


Sorted Z-values histogram for motif Ddit3

Sorted Z-values for motif Ddit3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ddit3

PNG image of the network

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Top targets:


Showing 1 to 20 of 141 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_109823585 3.142 ENSMUST00000161582.1
 Nav3
neuron navigator 3
chr9_-_121495678 2.582 ENSMUST00000035120.4
 Cck
cholecystokinin
chrX_+_103422010 2.314 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr19_-_59076069 2.274 ENSMUST00000047511.7
ENSMUST00000163821.1
 4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr10_+_112271123 2.092 ENSMUST00000092175.2
 Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr5_-_114273702 1.955 ENSMUST00000144050.1
ENSMUST00000044790.5
 Foxn4

forkhead box N4

chr15_-_66948419 1.906 ENSMUST00000167817.1
 Ndrg1
N-myc downstream regulated gene 1
chr11_-_35798884 1.772 ENSMUST00000160726.2
 Fbll1
fibrillarin-like 1
chr5_+_137553517 1.666 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
 Actl6b




actin-like 6B




chr3_+_90537306 1.648 ENSMUST00000107335.1
 S100a16
S100 calcium binding protein A16
chr8_-_99416397 1.551 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
 Cdh8




cadherin 8




chr3_+_90537242 1.551 ENSMUST00000098911.3
 S100a16
S100 calcium binding protein A16
chr3_-_92083132 1.453 ENSMUST00000058150.6
 Lor
loricrin
chr18_+_37421418 1.357 ENSMUST00000053073.4
 Pcdhb11
protocadherin beta 11
chr15_-_43869993 1.334 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr14_-_66868572 1.256 ENSMUST00000022629.8
 Dpysl2
dihydropyrimidinase-like 2
chr5_+_137288273 1.235 ENSMUST00000024099.4
ENSMUST00000085934.3
 Ache

acetylcholinesterase

chr14_+_65971164 1.207 ENSMUST00000144619.1
 Clu
clusterin
chr3_-_127408937 1.195 ENSMUST00000183095.1
ENSMUST00000182610.1
 Ank2

ankyrin 2, brain

chr6_+_21215472 1.186 ENSMUST00000081542.5
 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.5 3.2 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.0 3.2 GO:0051592 response to calcium ion(GO:0051592)
0.3 2.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.3 2.1 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.2 2.0 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 1.9 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.4 1.8 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 1.7 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.1 1.6 GO:0009409 response to cold(GO:0009409)
0.2 1.5 GO:0031424 keratinization(GO:0031424)
0.1 1.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.2 1.2 GO:0019695 choline metabolic process(GO:0019695)
0.1 1.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.4 1.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.3 1.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 1.0 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.3 GO:0031430 M band(GO:0031430)
0.1 3.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.5 3.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.2 2.6 GO:0043203 axon hillock(GO:0043203)
0.1 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.6 GO:0043083 synaptic cleft(GO:0043083)
0.4 1.5 GO:0001533 cornified envelope(GO:0001533)
0.1 1.2 GO:0005605 basal lamina(GO:0005605)
0.4 1.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.1 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.7 GO:0005912 adherens junction(GO:0005912)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 3.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 2.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.9 GO:0045296 cadherin binding(GO:0045296)
0.0 1.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 1.2 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.2 1.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 1.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.0 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 0.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 0.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)