Motif ID: Dlx1

Z-value: 1.048


Transcription factors associated with Dlx1:

Gene SymbolEntrez IDGene Name
Dlx1 ENSMUSG00000041911.3 Dlx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dlx1mm10_v2_chr2_+_71528657_715286830.413.6e-02Click!


Activity profile for motif Dlx1.

activity profile for motif Dlx1


Sorted Z-values histogram for motif Dlx1

Sorted Z-values for motif Dlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Dlx1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_170009892 4.016 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887
chr8_+_66386292 3.159 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr7_-_140154712 2.990 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr12_+_84069325 2.909 ENSMUST00000046422.4
ENSMUST00000072505.4
 Acot5

acyl-CoA thioesterase 5

chrX_+_150547375 2.892 ENSMUST00000066337.6
ENSMUST00000112715.1
 Alas2

aminolevulinic acid synthase 2, erythroid

chr19_-_11604828 2.765 ENSMUST00000025582.4
 Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr6_-_101377897 2.699 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr4_+_102570065 2.529 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr11_-_42182924 2.416 ENSMUST00000020707.5
ENSMUST00000132971.1
 Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chr11_-_98053415 2.365 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr18_-_43438280 2.356 ENSMUST00000121805.1
 Dpysl3
dihydropyrimidinase-like 3
chr6_+_145934113 2.278 ENSMUST00000032383.7
 Sspn
sarcospan
chr4_+_128058962 2.277 ENSMUST00000184063.1
 Csmd2
CUB and Sushi multiple domains 2
chrX_+_99042581 2.273 ENSMUST00000036606.7
 Stard8
START domain containing 8
chr1_-_22315792 2.190 ENSMUST00000164877.1
 Rims1
regulating synaptic membrane exocytosis 1
chr5_+_107403496 2.184 ENSMUST00000049146.5
 Ephx4
epoxide hydrolase 4
chr4_+_102589687 2.179 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr1_+_58210397 2.167 ENSMUST00000040442.5
 Aox4
aldehyde oxidase 4
chr18_+_23415400 1.993 ENSMUST00000115832.2
ENSMUST00000047954.7
 Dtna

dystrobrevin alpha

chr15_-_37458523 1.990 ENSMUST00000116445.2
 Ncald
neurocalcin delta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 3.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 3.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 3.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 3.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.7 2.9 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 2.9 GO:0031032 actomyosin structure organization(GO:0031032)
0.3 2.8 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.6 2.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 2.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.3 2.4 GO:0071420 cellular response to histamine(GO:0071420)
0.7 2.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.6 2.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.5 2.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 2.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 2.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 2.0 GO:0019532 oxalate transport(GO:0019532)
0.0 2.0 GO:0019882 antigen processing and presentation(GO:0019882)
0.6 1.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 1.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 4.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 4.2 GO:0042734 presynaptic membrane(GO:0042734)
0.2 3.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 3.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.6 2.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.4 GO:0030027 lamellipodium(GO:0030027)
0.0 2.3 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.2 GO:0043205 fibril(GO:0043205)
0.0 2.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.1 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.8 GO:0042581 specific granule(GO:0042581)
0.0 1.8 GO:0031672 A band(GO:0031672)
0.0 1.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.7 GO:0043015 cAMP binding(GO:0030552) gamma-tubulin binding(GO:0043015)
0.3 4.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 4.3 GO:0017124 SH3 domain binding(GO:0017124)
0.2 3.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 3.3 GO:0003924 GTPase activity(GO:0003924)
0.6 3.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 3.1 GO:0042287 MHC protein binding(GO:0042287)
0.1 3.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 2.9 GO:0016594 glycine binding(GO:0016594)
0.5 2.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.6 2.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.5 2.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 2.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.7 2.0 GO:0019770 IgG receptor activity(GO:0019770)
0.2 2.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 2.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)