Motif ID: E2f2_E2f5

Z-value: 5.393

Transcription factors associated with E2f2_E2f5:

Gene SymbolEntrez IDGene Name
E2f2 ENSMUSG00000018983.9 E2f2
E2f5 ENSMUSG00000027552.8 E2f5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f2mm10_v2_chr4_+_136172367_1361723950.972.9e-16Click!
E2f5mm10_v2_chr3_+_14578609_145786870.883.0e-09Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of E2f2_E2f5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 42.940 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr2_-_157204483 40.938 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr4_+_136172367 38.521 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr7_-_137314394 37.167 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr4_+_126556935 33.046 ENSMUST00000048391.8
Clspn
claspin
chr15_-_58135047 29.782 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chr4_+_126556994 28.288 ENSMUST00000147675.1
Clspn
claspin
chr13_-_24761861 28.027 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr12_+_24708241 27.475 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr17_+_56304313 27.255 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr9_+_122951051 26.715 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr10_+_110745433 26.234 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7



E2F transcription factor 7



chr13_-_24761440 26.180 ENSMUST00000176890.1
ENSMUST00000175689.1
Gmnn

geminin

chr6_+_4747306 25.387 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr2_-_113848655 24.682 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr2_-_113848601 22.737 ENSMUST00000110949.2
Arhgap11a
Rho GTPase activating protein 11A
chr8_+_75109528 22.466 ENSMUST00000164309.1
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr10_-_5805412 21.427 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr1_-_20820213 21.343 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chrX_-_93632113 21.140 ENSMUST00000006856.2
Pola1
polymerase (DNA directed), alpha 1
chr13_+_92354783 21.040 ENSMUST00000022218.4
Dhfr
dihydrofolate reductase
chr2_+_119112793 20.755 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chrX_-_51205773 20.263 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr15_-_9140374 20.171 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr10_-_69352886 20.145 ENSMUST00000119827.1
ENSMUST00000020099.5
Cdk1

cyclin-dependent kinase 1

chr4_+_115000156 19.233 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr15_-_55090422 18.585 ENSMUST00000110231.1
ENSMUST00000023059.6
Dscc1

defective in sister chromatid cohesion 1 homolog (S. cerevisiae)

chr10_-_60219260 18.251 ENSMUST00000135158.2
Chst3
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chr2_+_132816141 18.142 ENSMUST00000028831.8
ENSMUST00000066559.5
Mcm8

minichromosome maintenance deficient 8 (S. cerevisiae)

chr11_+_80089385 17.682 ENSMUST00000108239.1
ENSMUST00000017694.5
Atad5

ATPase family, AAA domain containing 5

chr4_+_115000174 17.549 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr1_-_128359610 17.535 ENSMUST00000027601.4
Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr5_+_114130386 16.717 ENSMUST00000031587.6
Ung
uracil DNA glycosylase
chr6_-_88898664 16.547 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr12_-_69228167 16.507 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr2_+_72476159 16.167 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr1_-_191575534 15.774 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr14_-_31019055 15.419 ENSMUST00000037739.6
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chrX_-_51205990 14.806 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr13_-_64153194 14.704 ENSMUST00000059817.4
ENSMUST00000117241.1
Zfp367

zinc finger protein 367

chr7_-_48881032 14.520 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr12_-_11265768 14.495 ENSMUST00000166117.1
Gen1
Gen homolog 1, endonuclease (Drosophila)
chrX_+_42151002 14.448 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr12_+_24708984 14.078 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr2_+_72476225 13.768 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr7_+_110122299 13.521 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr9_+_64281575 13.320 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr7_-_48881596 13.302 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr12_+_116405397 13.033 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr12_+_71016658 12.561 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr3_-_95217877 12.393 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr17_+_56303396 12.330 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr3_-_95217690 11.843 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr5_+_110286306 11.638 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chrX_+_42150672 11.582 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr16_-_15637277 11.382 ENSMUST00000023353.3
Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr3_+_98013503 10.900 ENSMUST00000079812.6
Notch2
notch 2
chr1_-_86359455 10.720 ENSMUST00000027438.6
Ncl
nucleolin
chr13_+_113035111 10.542 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr14_-_20388822 10.416 ENSMUST00000022345.6
Dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr1_+_175880775 10.263 ENSMUST00000039725.6
Exo1
exonuclease 1
chr9_-_20952838 9.635 ENSMUST00000004202.9
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr3_+_41563356 9.293 ENSMUST00000163764.1
Phf17
PHD finger protein 17
chr9_+_103305156 9.198 ENSMUST00000035164.3
Topbp1
topoisomerase (DNA) II binding protein 1
chr3_-_95217741 9.131 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr10_-_21160925 8.961 ENSMUST00000020158.6
Myb
myeloblastosis oncogene
chr6_+_51470633 8.849 ENSMUST00000114445.1
ENSMUST00000114446.1
ENSMUST00000141711.1
Cbx3


chromobox 3


chr15_+_102296256 8.751 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr2_-_154569845 8.710 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr3_+_96104498 8.708 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
Otud7b



OTU domain containing 7B



chr4_+_32615473 8.622 ENSMUST00000178925.1
ENSMUST00000029950.3
Casp8ap2

caspase 8 associated protein 2

chr19_+_8723478 8.461 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1

small nucleolar RNA host gene (non-protein coding) 1

chr16_-_18811615 8.383 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr9_+_109875541 8.305 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr7_-_6730412 8.277 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr13_-_55329723 8.190 ENSMUST00000021941.7
Mxd3
Max dimerization protein 3
chr1_+_184034381 8.143 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr4_+_132768325 8.130 ENSMUST00000102561.4
Rpa2
replication protein A2
chr9_+_65630552 7.955 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr10_+_13090788 7.909 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1


pleiomorphic adenoma gene-like 1


chr8_+_95633500 7.815 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr7_-_44548733 7.792 ENSMUST00000145956.1
ENSMUST00000049343.8
Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr9_-_36726374 7.752 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr19_+_53600377 7.584 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chrX_+_50841434 7.569 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr9_-_13827029 7.514 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr9_+_65890237 7.506 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr7_-_38107490 7.505 ENSMUST00000108023.3
Ccne1
cyclin E1
chr14_+_51984857 7.496 ENSMUST00000100639.4
ENSMUST00000182909.1
ENSMUST00000182760.1
ENSMUST00000182061.1
ENSMUST00000182193.1
Arhgef40




Rho guanine nucleotide exchange factor (GEF) 40




chr7_+_13278778 7.471 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr14_+_51984826 7.458 ENSMUST00000093813.5
Arhgef40
Rho guanine nucleotide exchange factor (GEF) 40
chr17_+_56303321 7.343 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr1_+_157412352 7.286 ENSMUST00000061537.5
2810025M15Rik
RIKEN cDNA 2810025M15 gene
chr10_-_7956223 7.269 ENSMUST00000146444.1
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr2_+_150909565 7.147 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr2_-_5012716 7.127 ENSMUST00000027980.7
Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr2_-_154569720 6.992 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr9_-_97018823 6.923 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr12_+_112644828 6.900 ENSMUST00000021728.4
ENSMUST00000109755.3
Siva1

SIVA1, apoptosis-inducing factor

chr15_-_8444449 6.886 ENSMUST00000052965.6
Nipbl
Nipped-B homolog (Drosophila)
chr17_+_23726336 6.843 ENSMUST00000024701.7
Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
chr5_+_52741569 6.822 ENSMUST00000031081.4
ENSMUST00000031082.6
Pi4k2b

phosphatidylinositol 4-kinase type 2 beta

chr10_+_11281583 6.786 ENSMUST00000070300.4
Fbxo30
F-box protein 30
chr14_+_59625281 6.667 ENSMUST00000053949.5
Shisa2
shisa homolog 2 (Xenopus laevis)
chr12_+_11265867 6.667 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr2_+_53192067 6.533 ENSMUST00000028336.6
Arl6ip6
ADP-ribosylation factor-like 6 interacting protein 6
chr6_+_113531675 6.503 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr15_-_79605084 6.428 ENSMUST00000023065.6
Dmc1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
chr10_+_128232065 6.406 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr7_+_79392305 6.405 ENSMUST00000117227.1
ENSMUST00000118959.1
ENSMUST00000036865.6
Fanci


Fanconi anemia, complementation group I


chr1_+_131910458 6.356 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_+_110839973 6.287 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr14_-_67933512 6.168 ENSMUST00000039135.4
Dock5
dedicator of cytokinesis 5
chr3_+_127553462 6.152 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr9_-_72491939 6.088 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr4_+_11191354 6.084 ENSMUST00000170901.1
Ccne2
cyclin E2
chr5_-_138172383 5.953 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_-_100121512 5.894 ENSMUST00000032969.7
Pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr1_-_9700209 5.454 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr17_+_29490812 5.385 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr6_-_148946146 5.370 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr5_-_138171813 5.369 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr11_+_79993062 5.343 ENSMUST00000017692.8
ENSMUST00000163272.1
Suz12

suppressor of zeste 12 homolog (Drosophila)

chr8_-_53638945 5.321 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr14_-_104467984 5.250 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr16_-_18248697 5.172 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr2_-_132253227 5.167 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr17_-_71475285 5.150 ENSMUST00000127430.1
Smchd1
SMC hinge domain containing 1
chr13_-_47106176 5.138 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chr11_+_98907801 5.114 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chrX_+_112311334 5.084 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr15_+_55557399 5.044 ENSMUST00000022998.7
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr7_+_102441685 5.043 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr1_+_93803945 5.019 ENSMUST00000027505.6
Ing5
inhibitor of growth family, member 5
chr19_-_5964132 5.012 ENSMUST00000025752.7
ENSMUST00000165143.1
Pola2

polymerase (DNA directed), alpha 2

chr11_+_108920342 4.936 ENSMUST00000052915.7
Axin2
axin2
chr8_+_87472805 4.925 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
Gm2694


predicted gene 2694


chr13_+_22043189 4.856 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr6_+_51470510 4.786 ENSMUST00000031862.7
Cbx3
chromobox 3
chr4_-_126968124 4.779 ENSMUST00000106108.2
Zmym4
zinc finger, MYM-type 4
chr19_-_10203880 4.764 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr17_+_87975044 4.725 ENSMUST00000005503.3
Msh6
mutS homolog 6 (E. coli)
chr5_-_149051604 4.719 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr8_+_72135247 4.500 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr8_-_105707933 4.475 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chrX_-_73458990 4.445 ENSMUST00000033737.8
ENSMUST00000077243.4
Haus7

HAUS augmin-like complex, subunit 7

chr2_+_70474923 4.424 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr2_+_103970221 4.399 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr15_+_55557575 4.394 ENSMUST00000170046.1
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr2_+_129800451 4.316 ENSMUST00000165413.2
ENSMUST00000166282.2
Stk35

serine/threonine kinase 35

chr5_-_31108218 4.273 ENSMUST00000182776.1
ENSMUST00000182444.1
Slc30a3

solute carrier family 30 (zinc transporter), member 3

chr4_-_132843111 4.250 ENSMUST00000105919.1
ENSMUST00000030702.7
Ppp1r8

protein phosphatase 1, regulatory (inhibitor) subunit 8

chr4_-_107683576 4.043 ENSMUST00000131776.1
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr17_+_28801090 4.030 ENSMUST00000004985.9
Brpf3
bromodomain and PHD finger containing, 3
chr4_+_84884276 4.017 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chr2_+_103970115 4.016 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr7_-_30169701 3.999 ENSMUST00000062181.7
Zfp146
zinc finger protein 146
chr10_+_58323466 3.990 ENSMUST00000020078.7
Lims1
LIM and senescent cell antigen-like domains 1
chr11_+_88068242 3.968 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr2_-_170142673 3.938 ENSMUST00000109155.1
Zfp217
zinc finger protein 217
chr13_-_102958084 3.930 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr1_+_74661714 3.906 ENSMUST00000042125.8
ENSMUST00000141119.1
Ttll4

tubulin tyrosine ligase-like family, member 4

chr10_-_128891674 3.792 ENSMUST00000026408.6
Gdf11
growth differentiation factor 11
chr3_-_127553233 3.775 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr13_-_106936907 3.752 ENSMUST00000080856.7
Ipo11
importin 11
chr1_+_15805639 3.742 ENSMUST00000027057.6
Terf1
telomeric repeat binding factor 1
chr8_+_87473116 3.714 ENSMUST00000182650.1
ENSMUST00000182758.1
ENSMUST00000181898.1
Gm2694


predicted gene 2694


chr1_+_74661794 3.708 ENSMUST00000129890.1
Ttll4
tubulin tyrosine ligase-like family, member 4
chr4_-_143299498 3.658 ENSMUST00000030317.7
Pdpn
podoplanin
chr3_+_104638658 3.638 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr12_+_111166413 3.628 ENSMUST00000021706.4
Traf3
TNF receptor-associated factor 3
chr3_+_116594959 3.543 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr15_+_9140527 3.520 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr5_+_88764983 3.491 ENSMUST00000031311.9
Dck
deoxycytidine kinase
chrX_-_8074720 3.489 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr2_-_132815978 3.488 ENSMUST00000039554.6
Trmt6
tRNA methyltransferase 6
chr14_-_34503323 3.470 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr4_+_95967322 3.467 ENSMUST00000107083.1
Hook1
hook homolog 1 (Drosophila)
chr1_-_38129618 3.426 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr15_+_8109313 3.398 ENSMUST00000163765.1
Nup155
nucleoporin 155
chr4_-_143299463 3.389 ENSMUST00000119654.1
Pdpn
podoplanin
chr7_-_130266191 3.374 ENSMUST00000122054.1
Fgfr2
fibroblast growth factor receptor 2
chr11_-_87404380 3.302 ENSMUST00000067692.6
Rad51c
RAD51 homolog C
chr7_-_130266237 3.300 ENSMUST00000117872.1
ENSMUST00000120187.1
Fgfr2

fibroblast growth factor receptor 2

chr2_+_85037212 3.282 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr4_+_108459389 3.277 ENSMUST00000106673.1
ENSMUST00000043368.5
Zcchc11

zinc finger, CCHC domain containing 11

chr8_+_87472838 3.270 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chrX_-_139871637 3.181 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr9_-_108452377 3.165 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr11_+_88718442 3.125 ENSMUST00000138007.1
C030037D09Rik
RIKEN cDNA C030037D09 gene
chr6_+_14901344 3.124 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr16_-_5255923 3.075 ENSMUST00000139584.1
ENSMUST00000064635.5
Fam86

family with sequence similarity 86

chr9_-_111271568 3.016 ENSMUST00000035079.3
Mlh1
mutL homolog 1 (E. coli)
chr6_-_47594967 2.993 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
Ezh2


enhancer of zeste homolog 2 (Drosophila)


chr12_+_111166349 2.936 ENSMUST00000117269.1
Traf3
TNF receptor-associated factor 3
chr5_-_110286159 2.895 ENSMUST00000031472.5
Pxmp2
peroxisomal membrane protein 2
chr18_-_46198810 2.882 ENSMUST00000167364.1
Trim36
tripartite motif-containing 36
chr4_+_84884418 2.851 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr1_-_157412576 2.844 ENSMUST00000078308.6
ENSMUST00000139470.1
Rasal2

RAS protein activator like 2

chr19_+_16956110 2.833 ENSMUST00000087689.4
Prune2
prune homolog 2 (Drosophila)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
18.0 54.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
7.7 54.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
7.7 61.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
6.0 77.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
5.6 16.7 GO:0006285 base-excision repair, AP site formation(GO:0006285)
5.4 42.9 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
5.4 21.4 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
5.3 21.2 GO:0071139 resolution of recombination intermediates(GO:0071139)
5.3 21.0 GO:0046655 glycine biosynthetic process(GO:0006545) folic acid metabolic process(GO:0046655)
5.0 19.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
5.0 29.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
4.6 36.8 GO:0033504 floor plate development(GO:0033504)
4.4 17.7 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
4.3 102.5 GO:0006270 DNA replication initiation(GO:0006270)
4.2 41.6 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
4.1 24.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
4.0 56.6 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
3.7 18.6 GO:0034421 post-translational protein acetylation(GO:0034421)
3.6 14.6 GO:0098763 mitotic cell cycle phase(GO:0098763)
3.6 10.9 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
3.3 13.3 GO:0000076 DNA replication checkpoint(GO:0000076)
3.3 23.3 GO:0019985 translesion synthesis(GO:0019985)
3.1 31.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
2.7 21.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
2.7 10.7 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
2.5 20.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
2.4 14.6 GO:1902969 mitotic DNA replication(GO:1902969)
2.2 33.4 GO:0034501 protein localization to kinetochore(GO:0034501)
2.2 6.7 GO:0035604 orbitofrontal cortex development(GO:0021769) fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
2.2 20.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
2.2 12.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
2.1 12.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
2.0 8.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
1.9 9.7 GO:0042148 strand invasion(GO:0042148)
1.8 5.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.7 8.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.7 8.6 GO:0036337 Fas signaling pathway(GO:0036337)
1.7 6.9 GO:0061010 gall bladder development(GO:0061010)
1.7 5.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
1.6 4.7 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
1.5 6.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
1.5 5.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.3 6.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.3 5.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
1.2 3.7 GO:0031627 telomeric loop formation(GO:0031627)
1.2 4.9 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
1.2 3.5 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
1.2 3.5 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.2 56.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
1.2 3.5 GO:0048352 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
1.1 3.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
1.1 5.6 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
1.1 15.4 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
1.1 8.8 GO:0000212 meiotic spindle organization(GO:0000212)
1.1 3.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.1 5.3 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
1.1 10.5 GO:0008063 Toll signaling pathway(GO:0008063)
1.0 28.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.0 13.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.0 4.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
1.0 4.8 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.9 2.8 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.9 9.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.9 39.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.9 3.5 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.8 7.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.8 5.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.8 8.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.8 5.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.8 2.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.8 5.4 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.8 6.9 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.7 7.0 GO:0015884 positive regulation of platelet activation(GO:0010572) folic acid transport(GO:0015884)
0.6 8.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.6 1.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825) positive regulation of centrosome cycle(GO:0046607)
0.6 3.0 GO:0045605 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984) negative regulation of epidermal cell differentiation(GO:0045605)
0.6 1.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.5 1.6 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.5 3.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.5 1.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.5 6.4 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.5 1.9 GO:0072697 protein localization to cell cortex(GO:0072697)
0.5 8.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.5 4.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.5 3.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.4 6.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.4 1.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 3.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.4 0.8 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.4 25.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.4 7.5 GO:0034453 microtubule anchoring(GO:0034453)
0.4 3.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 1.1 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.3 1.4 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 3.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 4.4 GO:0030238 male sex determination(GO:0030238) Leydig cell differentiation(GO:0033327)
0.3 0.7 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.3 5.1 GO:0042407 cristae formation(GO:0042407)
0.3 2.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 6.2 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.3 0.9 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.3 2.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.3 1.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.3 11.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.3 1.3 GO:0060056 mammary gland involution(GO:0060056)
0.3 15.3 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.3 2.8 GO:0080009 mRNA methylation(GO:0080009)
0.3 0.8 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 2.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 0.5 GO:0023035 CD40 signaling pathway(GO:0023035)
0.2 6.7 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2 4.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.2 1.7 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.2 0.9 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.2 2.8 GO:0060968 regulation of gene silencing(GO:0060968)
0.2 1.1 GO:0006983 ER overload response(GO:0006983)
0.2 4.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 1.0 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.0 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.2 1.0 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.2 3.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 4.6 GO:0006284 base-excision repair(GO:0006284)
0.2 4.8 GO:0007099 centriole replication(GO:0007099)
0.2 0.7 GO:1904008 cellular response to salt(GO:1902075) response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.2 4.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 2.7 GO:2000772 regulation of cellular senescence(GO:2000772)
0.2 0.8 GO:0072488 nitrogen utilization(GO:0019740) ammonium transmembrane transport(GO:0072488)
0.2 3.8 GO:0021511 spinal cord patterning(GO:0021511)
0.2 2.3 GO:0002021 response to dietary excess(GO:0002021)
0.2 0.5 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.2 2.4 GO:0043486 histone exchange(GO:0043486)
0.1 1.8 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.3 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.4 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 3.6 GO:0032094 response to food(GO:0032094)
0.1 3.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.7 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 2.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 2.9 GO:0007340 acrosome reaction(GO:0007340)
0.1 3.5 GO:0030488 tRNA methylation(GO:0030488)
0.1 2.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 4.5 GO:0007569 cell aging(GO:0007569)
0.1 1.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.6 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.8 GO:0007020 microtubule nucleation(GO:0007020)
0.1 14.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 12.2 GO:0048511 rhythmic process(GO:0048511)
0.1 5.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 2.4 GO:0048477 oogenesis(GO:0048477)
0.1 6.1 GO:0007548 sex differentiation(GO:0007548)
0.1 0.5 GO:0007197 gastric acid secretion(GO:0001696) adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.3 GO:0030242 pexophagy(GO:0030242)
0.1 1.1 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.1 11.8 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.1 2.0 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.1 4.0 GO:0001885 endothelial cell development(GO:0001885)
0.1 4.4 GO:0051225 spindle assembly(GO:0051225)
0.1 1.6 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 7.9 GO:0006260 DNA replication(GO:0006260)
0.1 2.5 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 4.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.6 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 33.9 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 0.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 1.7 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 1.5 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.0 0.3 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 3.3 GO:0006468 protein phosphorylation(GO:0006468)
0.0 3.2 GO:0006915 apoptotic process(GO:0006915)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 46.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
8.7 26.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
7.9 118.1 GO:0042555 MCM complex(GO:0042555)
7.1 7.1 GO:0031298 replication fork protection complex(GO:0031298)
5.3 26.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
3.1 15.7 GO:0035189 Rb-E2F complex(GO:0035189)
2.8 28.3 GO:0000800 lateral element(GO:0000800)
2.8 8.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.7 8.2 GO:0035061 interchromatin granule(GO:0035061)
2.6 15.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
2.6 7.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
2.3 18.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
2.1 10.7 GO:0001651 dense fibrillar component(GO:0001651)
1.8 5.5 GO:0000811 GINS complex(GO:0000811) DNA replication preinitiation complex(GO:0031261)
1.7 5.2 GO:0070557 PCNA-p21 complex(GO:0070557)
1.6 15.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.5 12.2 GO:0001673 male germ cell nucleus(GO:0001673)
1.4 71.0 GO:0005657 replication fork(GO:0005657)
1.2 8.4 GO:0032300 mismatch repair complex(GO:0032300)
1.2 7.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.2 3.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
1.1 3.2 GO:0018444 translation release factor complex(GO:0018444)
0.9 1.7 GO:0000801 central element(GO:0000801)
0.7 5.1 GO:0001740 Barr body(GO:0001740)
0.7 10.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.7 3.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.7 3.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.7 5.4 GO:0016580 Sin3 complex(GO:0016580)
0.6 8.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.6 3.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.6 3.7 GO:0070187 telosome(GO:0070187)
0.6 5.1 GO:0061617 MICOS complex(GO:0061617)
0.6 4.4 GO:0070652 HAUS complex(GO:0070652)
0.6 11.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 3.5 GO:0070695 FHF complex(GO:0070695)
0.5 5.2 GO:1904115 axon cytoplasm(GO:1904115)
0.5 29.3 GO:0005871 kinesin complex(GO:0005871)
0.4 45.1 GO:0005814 centriole(GO:0005814)
0.4 29.3 GO:0072686 mitotic spindle(GO:0072686)
0.4 2.8 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 1.5 GO:0001652 granular component(GO:0001652)
0.4 1.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.4 1.1 GO:0031251 PAN complex(GO:0031251)
0.4 1.1 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.3 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 134.3 GO:0005667 transcription factor complex(GO:0005667)
0.3 2.2 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.3 20.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 3.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 1.4 GO:0005683 U7 snRNP(GO:0005683)
0.3 6.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 1.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 41.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.2 1.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 15.7 GO:0016605 PML body(GO:0016605)
0.2 2.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 0.6 GO:0090543 Flemming body(GO:0090543)
0.2 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 4.5 GO:0002102 podosome(GO:0002102)
0.2 5.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 2.8 GO:0097470 ribbon synapse(GO:0097470)
0.2 10.0 GO:0000793 condensed chromosome(GO:0000793)
0.2 1.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 8.7 GO:0000922 spindle pole(GO:0000922)
0.1 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 8.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 3.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.7 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0005638 lamin filament(GO:0005638)
0.1 4.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 175.1 GO:0005654 nucleoplasm(GO:0005654)
0.1 2.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 1.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 3.5 GO:0005901 caveola(GO:0005901)
0.1 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 7.0 GO:0030027 lamellipodium(GO:0030027)
0.1 31.1 GO:0005730 nucleolus(GO:0005730)
0.1 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 2.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 11.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 173.5 GO:0005634 nucleus(GO:0005634)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 4.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.5 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
15.6 46.9 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
10.2 61.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
9.3 46.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
7.0 21.0 GO:0051870 methotrexate binding(GO:0051870)
6.8 54.5 GO:0003688 DNA replication origin binding(GO:0003688)
4.6 18.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
4.4 30.5 GO:0000150 recombinase activity(GO:0000150)
3.8 15.0 GO:0048256 flap endonuclease activity(GO:0048256)
3.6 14.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
3.5 24.6 GO:0003896 DNA primase activity(GO:0003896)
3.0 3.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
3.0 12.0 GO:0036033 mediator complex binding(GO:0036033)
3.0 53.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
2.7 13.5 GO:0032135 DNA insertion or deletion binding(GO:0032135)
2.6 7.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.1 8.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.8 10.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.7 8.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.7 18.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.7 45.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.6 4.7 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.4 22.0 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.4 6.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.3 15.9 GO:1990226 histone methyltransferase binding(GO:1990226)
1.3 20.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.2 14.9 GO:0031996 thioesterase binding(GO:0031996)
1.2 7.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.2 8.6 GO:0032184 SUMO polymer binding(GO:0032184)
1.1 4.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
1.1 5.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.1 12.9 GO:0070182 DNA polymerase binding(GO:0070182)
1.1 67.1 GO:0003678 DNA helicase activity(GO:0003678)
0.9 3.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.8 7.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.7 6.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.7 3.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.6 3.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.6 107.6 GO:0001047 core promoter binding(GO:0001047)
0.6 3.5 GO:0051525 NFAT protein binding(GO:0051525)
0.6 3.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.6 3.5 GO:0098821 BMP receptor activity(GO:0098821)
0.6 1.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.5 43.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.5 1.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5 1.4 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.5 3.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.5 3.6 GO:0001618 virus receptor activity(GO:0001618)
0.4 29.3 GO:0003777 microtubule motor activity(GO:0003777)
0.4 5.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.4 2.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.4 8.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.4 3.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 1.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 0.3 GO:0016751 S-succinyltransferase activity(GO:0016751)
0.3 13.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 5.1 GO:0070411 I-SMAD binding(GO:0070411)
0.3 10.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 18.2 GO:0035064 methylated histone binding(GO:0035064)
0.3 6.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 8.4 GO:0070888 E-box binding(GO:0070888)
0.3 1.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.3 4.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 30.7 GO:0042393 histone binding(GO:0042393)
0.2 3.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 1.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 9.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 5.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 67.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 2.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 37.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.2 4.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 2.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 18.3 GO:0004386 helicase activity(GO:0004386)
0.2 2.3 GO:0031386 protein tag(GO:0031386)
0.2 49.3 GO:0005096 GTPase activator activity(GO:0005096)
0.2 14.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 15.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 0.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 3.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 8.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 22.5 GO:0003682 chromatin binding(GO:0003682)
0.1 1.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 8.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.3 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.1 1.6 GO:0048038 quinone binding(GO:0048038)
0.1 2.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 4.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 35.1 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.1 3.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 4.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 17.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 9.7 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.1 GO:0004772 sterol O-acyltransferase activity(GO:0004772)
0.1 5.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 6.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.5 GO:0002039 p53 binding(GO:0002039)
0.0 1.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 6.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.1 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) rRNA methyltransferase activity(GO:0008649) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) DNA-methyltransferase activity(GO:0009008) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) rRNA (uridine) methyltransferase activity(GO:0016436) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 6.7 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)