Motif ID: E2f7

Z-value: 1.385


Transcription factors associated with E2f7:

Gene SymbolEntrez IDGene Name
E2f7 ENSMUSG00000020185.10 E2f7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f7mm10_v2_chr10_+_110745433_1107455720.572.3e-03Click!


Activity profile for motif E2f7.

activity profile for motif E2f7


Sorted Z-values histogram for motif E2f7

Sorted Z-values for motif E2f7



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f7

PNG image of the network

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Top targets:


Showing 1 to 20 of 131 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_116308241 6.248 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
 Plekha7


pleckstrin homology domain containing, family A member 7


chr9_+_3037111 4.252 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr4_+_108579445 3.989 ENSMUST00000102744.3
 Orc1
origin recognition complex, subunit 1
chr9_+_3013140 3.945 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr9_+_3025417 3.723 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr12_+_24708984 3.586 ENSMUST00000154588.1
 Rrm2
ribonucleotide reductase M2
chr9_+_3017408 3.201 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3015654 3.155 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr11_+_102248842 3.114 ENSMUST00000100392.4
 BC030867
cDNA sequence BC030867
chr13_-_100775844 3.096 ENSMUST00000075550.3
 Cenph
centromere protein H
chr10_+_3973086 3.073 ENSMUST00000117291.1
ENSMUST00000120585.1
ENSMUST00000043735.7
 Mthfd1l


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr15_+_102296256 2.832 ENSMUST00000064924.4
 Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr2_-_157204483 2.738 ENSMUST00000029170.7
 Rbl1
retinoblastoma-like 1 (p107)
chr10_+_11281304 2.697 ENSMUST00000129456.1
 Fbxo30
F-box protein 30
chr10_-_69352886 2.670 ENSMUST00000119827.1
ENSMUST00000020099.5
 Cdk1

cyclin-dependent kinase 1

chr12_+_24708241 2.624 ENSMUST00000020980.5
 Rrm2
ribonucleotide reductase M2
chr10_+_11281583 2.419 ENSMUST00000070300.4
 Fbxo30
F-box protein 30
chr6_-_67037399 2.392 ENSMUST00000043098.6
 Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr3_+_108383829 2.339 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
 Psrc1


proline/serine-rich coiled-coil 1


chr4_+_126556994 2.079 ENSMUST00000147675.1
 Clspn
claspin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 6.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.6 6.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.3 4.4 GO:0051382 kinetochore assembly(GO:0051382)
1.0 4.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.5 3.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 3.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.6 3.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.4 2.8 GO:1901970 positive regulation of mitotic sister chromatid separation(GO:1901970)
0.2 2.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 2.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.2 2.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 2.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.2 2.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 2.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 2.0 GO:0090166 Golgi disassembly(GO:0090166)
0.1 2.0 GO:0006270 DNA replication initiation(GO:0006270)
0.4 1.7 GO:0071139 resolution of recombination intermediates(GO:0071139)
0.3 1.7 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.1 1.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.3 1.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 6.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.6 6.2 GO:0005915 zonula adherens(GO:0005915)
0.2 5.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.7 5.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 4.5 GO:0005876 spindle microtubule(GO:0005876)
0.1 3.6 GO:0000786 nucleosome(GO:0000786)
0.0 3.1 GO:0000776 kinetochore(GO:0000776)
0.0 2.8 GO:0072686 mitotic spindle(GO:0072686)
0.2 2.6 GO:0042555 MCM complex(GO:0042555)
0.5 1.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 1.0 GO:0070695 FHF complex(GO:0070695)
0.2 0.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.2 0.8 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 0.7 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.7 GO:0001651 dense fibrillar component(GO:0001651) granular component(GO:0001652)
0.1 0.7 GO:0001527 microfibril(GO:0001527)
0.1 0.6 GO:0000124 SAGA complex(GO:0000124)
0.1 0.5 GO:0042382 paraspeckles(GO:0042382)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.4 GO:0070097 delta-catenin binding(GO:0070097)
1.2 6.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 5.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.7 3.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 3.8 GO:0001047 core promoter binding(GO:0001047)
0.4 3.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 3.6 GO:0008017 microtubule binding(GO:0008017)
0.8 3.1 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 3.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.2 2.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.6 2.6 GO:0043515 kinetochore binding(GO:0043515)
0.0 2.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 2.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 2.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)