Motif ID: E2f8

Z-value: 2.050


Transcription factors associated with E2f8:

Gene SymbolEntrez IDGene Name
E2f8 ENSMUSG00000046179.11 E2f8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f8mm10_v2_chr7_-_48881596_488816190.973.3e-16Click!


Activity profile for motif E2f8.

activity profile for motif E2f8


Sorted Z-values histogram for motif E2f8

Sorted Z-values for motif E2f8



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_36726374 11.462 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1


chr5_+_123749696 9.898 ENSMUST00000031366.7
 Kntc1
kinetochore associated 1
chr17_+_56303321 9.540 ENSMUST00000001258.8
 Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr8_+_75109528 9.057 ENSMUST00000164309.1
 Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr12_+_24708984 8.980 ENSMUST00000154588.1
 Rrm2
ribonucleotide reductase M2
chr17_+_56040350 8.972 ENSMUST00000002914.8
 Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr17_+_56303396 7.915 ENSMUST00000113038.1
 Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr19_+_38931008 7.818 ENSMUST00000145051.1
 Hells
helicase, lymphoid specific
chr16_-_18811615 7.656 ENSMUST00000096990.3
 Cdc45
cell division cycle 45
chr7_-_48881032 7.592 ENSMUST00000058745.8
 E2f8
E2F transcription factor 8
chr19_+_38930909 7.387 ENSMUST00000025965.5
 Hells
helicase, lymphoid specific
chr12_+_24708241 7.230 ENSMUST00000020980.5
 Rrm2
ribonucleotide reductase M2
chr7_-_115824699 7.183 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr10_-_21160925 7.132 ENSMUST00000020158.6
 Myb
myeloblastosis oncogene
chr11_+_98907801 7.010 ENSMUST00000092706.6
 Cdc6
cell division cycle 6
chr7_-_48881596 6.927 ENSMUST00000119223.1
 E2f8
E2F transcription factor 8
chr6_-_94700137 6.547 ENSMUST00000101126.2
ENSMUST00000032105.4
 Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr11_-_89302545 6.457 ENSMUST00000061728.3
 Nog
noggin
chr2_+_163054682 6.186 ENSMUST00000018005.3
 Mybl2
myeloblastosis oncogene-like 2
chr16_-_46496955 6.055 ENSMUST00000023335.6
ENSMUST00000023334.8
 Pvrl3

poliovirus receptor-related 3

chr1_-_128359610 6.032 ENSMUST00000027601.4
 Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr6_-_88898664 5.854 ENSMUST00000058011.6
 Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr10_+_128015157 5.717 ENSMUST00000178041.1
ENSMUST00000026461.7
 Prim1

DNA primase, p49 subunit

chr5_-_65335597 5.569 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
 Rfc1


replication factor C (activator 1) 1


chr9_+_103305156 5.536 ENSMUST00000035164.3
 Topbp1
topoisomerase (DNA) II binding protein 1
chr5_-_65335564 5.391 ENSMUST00000172780.1
 Rfc1
replication factor C (activator 1) 1
chr5_+_111581422 5.085 ENSMUST00000064930.3
 C130026L21Rik
RIKEN cDNA C130026L21 gene
chr16_-_15637277 5.076 ENSMUST00000023353.3
 Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr7_+_110122299 4.904 ENSMUST00000033326.8
 Wee1
WEE 1 homolog 1 (S. pombe)
chr16_-_46496772 4.891 ENSMUST00000149901.1
ENSMUST00000096052.2
 Pvrl3

poliovirus receptor-related 3

chr2_-_157204483 4.880 ENSMUST00000029170.7
 Rbl1
retinoblastoma-like 1 (p107)
chr6_+_117916981 4.426 ENSMUST00000179478.1
 Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr5_-_33652296 4.414 ENSMUST00000151081.1
ENSMUST00000101354.3
 Slbp

stem-loop binding protein

chr4_+_132768325 4.272 ENSMUST00000102561.4
 Rpa2
replication protein A2
chr6_+_117917281 4.046 ENSMUST00000180020.1
ENSMUST00000177570.1
 Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chr1_+_131910458 3.871 ENSMUST00000062264.6
 Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr15_+_55557399 3.825 ENSMUST00000022998.7
 Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr5_+_150673739 3.662 ENSMUST00000016569.4
ENSMUST00000038900.8
 Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

chr11_+_26387194 3.574 ENSMUST00000109509.1
ENSMUST00000136830.1
 Fancl

Fanconi anemia, complementation group L

chr13_+_44731265 3.549 ENSMUST00000173246.1
 Jarid2
jumonji, AT rich interactive domain 2
chr10_+_19356558 3.459 ENSMUST00000053225.5
 Olig3
oligodendrocyte transcription factor 3
chr4_-_129189600 3.423 ENSMUST00000117497.1
ENSMUST00000117350.1
 S100pbp

S100P binding protein

chr16_+_10835046 3.390 ENSMUST00000037913.8
 Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr5_-_33652339 3.372 ENSMUST00000075670.6
 Slbp
stem-loop binding protein
chr7_-_44548733 3.361 ENSMUST00000145956.1
ENSMUST00000049343.8
 Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr4_-_129189512 3.330 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
 S100pbp


S100P binding protein


chr15_+_55557575 3.316 ENSMUST00000170046.1
 Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr4_-_129189646 3.304 ENSMUST00000106059.1
 S100pbp
S100P binding protein
chr2_+_145785980 3.181 ENSMUST00000110005.1
ENSMUST00000094480.4
 Rin2

Ras and Rab interactor 2

chr13_+_19623163 3.026 ENSMUST00000002883.5
 Sfrp4
secreted frizzled-related protein 4
chr7_+_102065713 2.971 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
 Trpc2


transient receptor potential cation channel, subfamily C, member 2


chr11_+_79993062 2.962 ENSMUST00000017692.8
ENSMUST00000163272.1
 Suz12

suppressor of zeste 12 homolog (Drosophila)

chr5_-_123749393 2.934 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
 Rsrc2


arginine/serine-rich coiled-coil 2


chr5_-_123749371 2.785 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
 Rsrc2


arginine/serine-rich coiled-coil 2


chr16_+_15637844 2.610 ENSMUST00000023352.8
 Prkdc
protein kinase, DNA activated, catalytic polypeptide
chr2_-_84743655 2.499 ENSMUST00000181711.1
 Gm19426
predicted gene, 19426
chr13_+_44731281 2.479 ENSMUST00000174086.1
 Jarid2
jumonji, AT rich interactive domain 2
chr2_-_34913976 2.462 ENSMUST00000028232.3
 Phf19
PHD finger protein 19
chr6_+_35177386 2.354 ENSMUST00000043815.9
 Nup205
nucleoporin 205
chr2_-_154569720 2.056 ENSMUST00000000894.5
 E2f1
E2F transcription factor 1
chr12_+_110279228 1.890 ENSMUST00000097228.4
 Dio3
deiodinase, iodothyronine type III
chr7_+_102065485 1.870 ENSMUST00000106950.1
ENSMUST00000146450.1
 Trpc2

transient receptor potential cation channel, subfamily C, member 2

chr5_+_129020069 1.866 ENSMUST00000031383.7
ENSMUST00000111343.1
 Ran

RAN, member RAS oncogene family

chr6_+_35177610 1.831 ENSMUST00000170234.1
 Nup205
nucleoporin 205
chr2_-_154569845 1.719 ENSMUST00000103145.4
 E2f1
E2F transcription factor 1
chr2_-_18048784 1.699 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr3_-_127553233 1.658 ENSMUST00000029588.5
 Larp7
La ribonucleoprotein domain family, member 7
chr16_-_18248697 1.573 ENSMUST00000115645.3
 Ranbp1
RAN binding protein 1
chr13_+_94875600 1.482 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chrX_+_73716712 1.467 ENSMUST00000114461.2
 Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr5_+_137787769 1.344 ENSMUST00000035852.7
 Zcwpw1
zinc finger, CW type with PWWP domain 1
chr6_+_38551786 1.318 ENSMUST00000161227.1
 Luc7l2
LUC7-like 2 (S. cerevisiae)
chr11_-_101785252 1.244 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr9_-_50659780 1.233 ENSMUST00000034567.3
 Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr11_+_77462325 1.113 ENSMUST00000102493.1
 Coro6
coronin 6
chr5_+_135187251 1.080 ENSMUST00000002825.5
 Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr12_+_109540979 1.032 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
 Meg3


maternally expressed 3


chr10_+_116301374 0.858 ENSMUST00000092167.5
 Ptprb
protein tyrosine phosphatase, receptor type, B
chrX_-_73716145 0.851 ENSMUST00000002091.5
 Bcap31
B cell receptor associated protein 31
chr6_-_87851011 0.846 ENSMUST00000113617.1
 Cnbp
cellular nucleic acid binding protein
chr11_+_88047693 0.704 ENSMUST00000079866.4
 Srsf1
serine/arginine-rich splicing factor 1
chr8_-_109737714 0.617 ENSMUST00000093162.3
 Atxn1l
ataxin 1-like
chr15_+_78926720 0.597 ENSMUST00000089377.5
 Lgals1
lectin, galactose binding, soluble 1
chrX_-_41911877 0.532 ENSMUST00000047037.8
 Thoc2
THO complex 2
chr7_-_27337667 0.454 ENSMUST00000038618.6
ENSMUST00000108369.2
 Ltbp4

latent transforming growth factor beta binding protein 4

chr1_-_168431695 0.309 ENSMUST00000176790.1
 Pbx1
pre B cell leukemia homeobox 1
chrX_+_73716577 0.303 ENSMUST00000002084.7
 Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr6_+_29348069 0.271 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
 Calu


calumenin


chr10_-_128525859 0.247 ENSMUST00000026427.6
 Esyt1
extended synaptotagmin-like protein 1
chr10_+_42860348 0.191 ENSMUST00000063063.7
 Scml4
sex comb on midleg-like 4 (Drosophila)
chr8_+_40926220 0.069 ENSMUST00000034004.9
 Pdgfrl
platelet-derived growth factor receptor-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.5 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
2.6 7.7 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
2.2 6.5 GO:0032474 otolith morphogenesis(GO:0032474)
2.2 32.7 GO:0010216 maintenance of DNA methylation(GO:0010216)
2.2 13.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
1.9 5.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.6 16.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
1.6 6.5 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.4 7.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.3 13.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
1.3 17.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.3 3.8 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
1.0 3.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
1.0 7.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.0 4.8 GO:0002121 inter-male aggressive behavior(GO:0002121) response to pheromone(GO:0019236)
0.7 16.1 GO:0006270 DNA replication initiation(GO:0006270)
0.7 3.5 GO:0097475 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.7 7.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.6 1.8 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.6 3.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.4 2.6 GO:0002326 B cell lineage commitment(GO:0002326) ectopic germ cell programmed cell death(GO:0035234)
0.4 3.0 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.4 1.9 GO:1902570 protein localization to nucleolus(GO:1902570)
0.4 2.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 4.2 GO:0000059 protein import into nucleus, docking(GO:0000059)
0.3 1.9 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.3 9.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 0.9 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 3.9 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.2 4.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 1.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2 5.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.2 1.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 1.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 6.2 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.1 4.9 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.6 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 9.9 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 2.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 1.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 10.2 GO:0006260 DNA replication(GO:0006260)
0.0 3.4 GO:0098792 xenophagy(GO:0098792)
0.0 4.2 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 2.5 GO:0043484 regulation of RNA splicing(GO:0043484)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:1990423 RZZ complex(GO:1990423)
3.2 16.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
3.0 9.0 GO:0033186 CAF-1 complex(GO:0033186)
2.6 7.7 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.8 11.0 GO:0005663 DNA replication factor C complex(GO:0005663)
1.7 25.7 GO:0042555 MCM complex(GO:0042555)
1.2 6.2 GO:0031523 Myb complex(GO:0031523)
1.1 3.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.1 7.8 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.8 4.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.8 3.8 GO:0035189 Rb-E2F complex(GO:0035189)
0.6 1.9 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.6 40.0 GO:0005657 replication fork(GO:0005657)
0.5 11.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 15.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.5 5.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 2.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.4 1.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 3.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 5.5 GO:0051233 spindle midzone(GO:0051233)
0.2 0.9 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.6 GO:1904115 axon cytoplasm(GO:1904115)
0.1 4.8 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 6.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 26.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 5.6 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
3.8 11.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
3.2 16.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.8 22.6 GO:0003688 DNA replication origin binding(GO:0003688)
2.6 7.8 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.9 13.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.1 9.0 GO:0070087 chromo shadow domain binding(GO:0070087)
1.0 11.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0 5.7 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.5 3.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.4 4.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 3.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 1.9 GO:0070883 importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883)
0.4 1.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 8.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 4.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 11.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 1.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 4.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 0.6 GO:0005534 galactose binding(GO:0005534)
0.2 6.0 GO:0032452 histone demethylase activity(GO:0032452)
0.2 2.6 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 6.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 10.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 15.2 GO:0004386 helicase activity(GO:0004386)
0.1 3.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 14.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 5.2 GO:0019955 cytokine binding(GO:0019955)
0.1 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 5.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 3.0 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 1.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 3.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.5 GO:0003682 chromatin binding(GO:0003682)