Motif ID: Ebf3

Z-value: 1.806


Transcription factors associated with Ebf3:

Gene SymbolEntrez IDGene Name
Ebf3 ENSMUSG00000010476.7 Ebf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf3mm10_v2_chr7_-_137314394_137314445-0.572.3e-03Click!


Activity profile for motif Ebf3.

activity profile for motif Ebf3


Sorted Z-values histogram for motif Ebf3

Sorted Z-values for motif Ebf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66812593 16.104 ENSMUST00000100572.3
 Sla
src-like adaptor
chr5_+_117781017 11.409 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr1_-_56969827 9.466 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr11_-_98053415 9.289 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr11_+_104231573 8.608 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
 Mapt


microtubule-associated protein tau


chr1_-_56969864 8.320 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr11_+_104231390 8.123 ENSMUST00000106992.3
 Mapt
microtubule-associated protein tau
chr11_-_98329641 7.667 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr11_+_104231515 7.560 ENSMUST00000106993.3
 Mapt
microtubule-associated protein tau
chr11_+_104231465 7.500 ENSMUST00000145227.1
 Mapt
microtubule-associated protein tau
chr4_-_129121234 7.309 ENSMUST00000030572.3
 Hpca
hippocalcin
chr1_-_173367638 7.207 ENSMUST00000005470.4
ENSMUST00000111220.1
 Cadm3

cell adhesion molecule 3

chr9_-_58313189 7.066 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr4_-_129121699 6.976 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
 Hpca


hippocalcin


chr5_-_139129662 6.912 ENSMUST00000026973.7
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr5_-_139130159 6.747 ENSMUST00000129851.1
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr8_+_70493156 6.655 ENSMUST00000008032.7
 Crlf1
cytokine receptor-like factor 1
chr7_+_123982799 6.606 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr19_+_4231899 6.206 ENSMUST00000025773.3
 Pold4
polymerase (DNA-directed), delta 4
chr18_-_31447383 5.738 ENSMUST00000025110.3
 Syt4
synaptotagmin IV

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 138 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 31.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
1.1 17.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
4.8 14.3 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.1 13.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
2.9 11.4 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.3 8.1 GO:0010107 potassium ion import(GO:0010107)
2.6 7.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 7.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 6.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
1.1 6.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.8 6.3 GO:0097460 ferrous iron import into cell(GO:0097460)
0.3 6.2 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.7 5.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.7 5.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.7 5.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.3 5.3 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.9 5.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.7 5.3 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.5 5.2 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
1.0 4.8 GO:0090273 regulation of somatostatin secretion(GO:0090273)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 84 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.2 31.8 GO:0045298 tubulin complex(GO:0045298)
1.4 14.3 GO:0044327 dendritic spine head(GO:0044327)
1.1 13.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 13.0 GO:0000118 histone deacetylase complex(GO:0000118)
1.0 11.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.8 11.3 GO:0031045 dense core granule(GO:0031045)
0.3 10.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 8.4 GO:0030315 T-tubule(GO:0030315)
0.2 7.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 7.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 7.3 GO:0005768 endosome(GO:0005768)
0.1 7.1 GO:0001669 acrosomal vesicle(GO:0001669)
2.2 6.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 6.3 GO:0031941 filamentous actin(GO:0031941)
2.1 6.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 6.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 5.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.5 5.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 5.3 GO:0008021 synaptic vesicle(GO:0008021)
0.3 5.2 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 29.5 GO:0034185 apolipoprotein binding(GO:0034185)
1.2 13.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
3.8 11.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 10.3 GO:0003682 chromatin binding(GO:0003682)
0.0 8.2 GO:0003779 actin binding(GO:0003779)
1.6 8.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 7.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 7.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.5 7.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
2.4 7.1 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.2 6.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 6.2 GO:0005080 protein kinase C binding(GO:0005080)
0.3 5.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.8 5.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 5.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.9 5.6 GO:0005042 netrin receptor activity(GO:0005042)
0.2 5.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.9 5.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.4 5.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 5.2 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)