Motif ID: Elf1_Elf2_Etv2_Elf4

Z-value: 2.901

Transcription factors associated with Elf1_Elf2_Etv2_Elf4:

Gene SymbolEntrez IDGene Name
Elf1 ENSMUSG00000036461.9 Elf1
Elf2 ENSMUSG00000037174.12 Elf2
Elf4 ENSMUSG00000031103.6 Elf4
Etv2 ENSMUSG00000006311.8 Etv2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf1mm10_v2_chr14_+_79515618_795156940.311.2e-01Click!
Elf2mm10_v2_chr3_-_51277470_512775140.232.6e-01Click!
Elf4mm10_v2_chrX_-_48454152_484541930.057.9e-01Click!


Activity profile for motif Elf1_Elf2_Etv2_Elf4.

activity profile for motif Elf1_Elf2_Etv2_Elf4


Sorted Z-values histogram for motif Elf1_Elf2_Etv2_Elf4

Sorted Z-values for motif Elf1_Elf2_Etv2_Elf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf1_Elf2_Etv2_Elf4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 10.025 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr11_-_94653964 9.959 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr2_-_156839790 9.880 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230


chr2_+_5845243 9.499 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr16_-_18811972 9.124 ENSMUST00000000028.7
ENSMUST00000115585.1
 Cdc45

cell division cycle 45

chr16_-_22161450 7.951 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_84839833 7.852 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr19_+_6084983 7.748 ENSMUST00000025704.2
 Cdca5
cell division cycle associated 5
chr16_+_48994185 7.112 ENSMUST00000117994.1
ENSMUST00000048374.5
 C330027C09Rik

RIKEN cDNA C330027C09 gene

chr4_-_45320580 6.896 ENSMUST00000030003.3
 Exosc3
exosome component 3
chr2_+_5845017 6.873 ENSMUST00000026927.3
ENSMUST00000179748.1
 Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr7_-_127042420 6.757 ENSMUST00000032915.6
 Kif22
kinesin family member 22
chr6_+_117906809 6.577 ENSMUST00000177918.1
ENSMUST00000163168.2
 Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chr7_-_122132844 6.504 ENSMUST00000106469.1
ENSMUST00000063587.6
ENSMUST00000106468.1
ENSMUST00000130149.1
ENSMUST00000098068.3
 Palb2




partner and localizer of BRCA2




chr3_-_89418287 6.410 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr2_-_101797650 6.315 ENSMUST00000141814.1
ENSMUST00000171088.1
ENSMUST00000043845.7
 Prr5l


proline rich 5 like


chr19_-_40271506 6.293 ENSMUST00000068439.6
 Pdlim1
PDZ and LIM domain 1 (elfin)
chr13_+_90089705 6.278 ENSMUST00000012566.8
 Tmem167
transmembrane protein 167
chr2_+_84840612 6.246 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1
chr2_+_156840077 6.192 ENSMUST00000081335.6
ENSMUST00000073352.3
 Tgif2

TGFB-induced factor homeobox 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,019 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 110.8 GO:0008380 RNA splicing(GO:0008380)
0.4 42.6 GO:0006413 translational initiation(GO:0006413)
1.0 30.3 GO:0006270 DNA replication initiation(GO:0006270)
0.7 24.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.9 24.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
1.1 22.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.8 21.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.7 20.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.6 20.0 GO:0006284 base-excision repair(GO:0006284)
0.7 19.1 GO:0030488 tRNA methylation(GO:0030488)
0.4 19.1 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.5 19.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.6 18.0 GO:0051310 metaphase plate congression(GO:0051310)
0.3 17.2 GO:0051028 mRNA transport(GO:0051028)
0.4 16.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.7 15.3 GO:0071539 protein localization to centrosome(GO:0071539)
2.5 14.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 13.6 GO:0007099 centriole replication(GO:0007099)
4.5 13.5 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.7 13.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 372 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 139.3 GO:0005730 nucleolus(GO:0005730)
0.7 63.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 55.3 GO:0005634 nucleus(GO:0005634)
0.7 53.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.9 43.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 39.4 GO:0005654 nucleoplasm(GO:0005654)
0.1 38.5 GO:0000785 chromatin(GO:0000785)
0.3 29.7 GO:0005681 spliceosomal complex(GO:0005681)
1.8 21.7 GO:0005687 U4 snRNP(GO:0005687)
0.3 21.6 GO:0005814 centriole(GO:0005814)
1.4 21.1 GO:0042555 MCM complex(GO:0042555)
0.1 20.5 GO:0005667 transcription factor complex(GO:0005667)
0.7 20.2 GO:0015030 Cajal body(GO:0015030)
0.4 18.8 GO:0072686 mitotic spindle(GO:0072686)
0.6 17.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 17.1 GO:0000791 euchromatin(GO:0000791)
0.4 16.3 GO:0005657 replication fork(GO:0005657)
2.3 16.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.5 15.2 GO:0030684 preribosome(GO:0030684)
0.3 14.7 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 560 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 134.9 GO:0044822 poly(A) RNA binding(GO:0044822)
0.4 68.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 49.0 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
1.2 35.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.6 35.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 33.4 GO:0042393 histone binding(GO:0042393)
0.4 32.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.6 30.3 GO:0000049 tRNA binding(GO:0000049)
0.4 26.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
3.2 25.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 25.7 GO:0019843 rRNA binding(GO:0019843)
2.2 22.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.3 21.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
1.4 21.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.9 19.6 GO:0030515 snoRNA binding(GO:0030515)
0.3 17.8 GO:0004386 helicase activity(GO:0004386)
0.3 17.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 17.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
1.9 17.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 16.3 GO:0000975 regulatory region DNA binding(GO:0000975)