Motif ID: Elf3

Z-value: 0.992


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.581.9e-03Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 4.791 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_+_164562579 3.831 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
 Wfdc2


WAP four-disulfide core domain 2


chr1_+_51987139 3.125 ENSMUST00000168302.1
 Stat4
signal transducer and activator of transcription 4
chr12_-_65172560 2.902 ENSMUST00000052201.8
 Mis18bp1
MIS18 binding protein 1
chr17_+_35049966 2.756 ENSMUST00000007257.9
 Clic1
chloride intracellular channel 1
chr19_+_16435616 2.627 ENSMUST00000025602.2
 Gna14
guanine nucleotide binding protein, alpha 14
chr19_+_25406661 2.380 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chr14_-_70207637 2.317 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr19_-_50678642 2.267 ENSMUST00000072685.6
ENSMUST00000164039.2
 Sorcs1

VPS10 domain receptor protein SORCS 1

chrX_+_169685191 2.160 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr9_+_91368811 2.135 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr4_-_106464167 2.125 ENSMUST00000049507.5
 Pcsk9
proprotein convertase subtilisin/kexin type 9
chr18_+_56432116 2.061 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr5_+_115845229 2.052 ENSMUST00000137952.1
ENSMUST00000148245.1
 Cit

citron

chr5_+_110330697 2.032 ENSMUST00000112481.1
 Pole
polymerase (DNA directed), epsilon
chr1_+_138963709 1.991 ENSMUST00000168527.1
 Dennd1b
DENN/MADD domain containing 1B
chr19_-_50678485 1.989 ENSMUST00000111756.3
 Sorcs1
VPS10 domain receptor protein SORCS 1
chr3_-_51396502 1.946 ENSMUST00000108046.1
 Mgarp
mitochondria localized glutamic acid rich protein
chr16_+_62854299 1.946 ENSMUST00000023629.8
 Pros1
protein S (alpha)
chr3_-_51396528 1.910 ENSMUST00000038154.5
 Mgarp
mitochondria localized glutamic acid rich protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 5.6 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.8 4.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 4.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.7 3.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 3.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.5 2.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 2.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.6 2.5 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 2.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.8 2.3 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 2.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 2.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.7 2.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.3 2.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 2.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 2.1 GO:0016579 protein deubiquitination(GO:0016579)
0.3 2.0 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.3 2.0 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.2 2.0 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.2 1.9 GO:0042730 fibrinolysis(GO:0042730)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 3.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.3 2.9 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 2.7 GO:0000776 kinetochore(GO:0000776)
0.4 2.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 2.4 GO:0031985 Golgi cisterna(GO:0031985)
0.7 2.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.7 2.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 2.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.7 2.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.4 2.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 2.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.0 GO:0005884 actin filament(GO:0005884)
0.4 1.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.8 GO:0051233 spindle midzone(GO:0051233)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.5 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0 5.7 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.2 3.9 GO:0017166 vinculin binding(GO:0017166)
0.0 3.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 3.2 GO:0030957 Tat protein binding(GO:0030957)
0.1 2.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.6 2.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 2.5 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.7 2.1 GO:0034190 very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
0.5 2.0 GO:0035877 death effector domain binding(GO:0035877)
0.1 2.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.6 1.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.6 1.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.7 GO:0005522 profilin binding(GO:0005522)
0.1 1.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 1.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)