Motif ID: Ep300

Z-value: 0.585


Transcription factors associated with Ep300:

Gene SymbolEntrez IDGene Name
Ep300 ENSMUSG00000055024.6 Ep300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ep300mm10_v2_chr15_+_81586206_81586250-0.814.2e-07Click!


Activity profile for motif Ep300.

activity profile for motif Ep300


Sorted Z-values histogram for motif Ep300

Sorted Z-values for motif Ep300



Network of associatons between targets according to the STRING database.



First level regulatory network of Ep300

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_98348404 3.418 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr8_-_84800344 2.133 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr6_+_99692679 1.853 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr9_-_29411736 1.746 ENSMUST00000115236.1
Ntm
neurotrimin
chr19_+_23758819 1.539 ENSMUST00000025830.7
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr11_-_116307168 1.185 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr7_+_96522342 1.154 ENSMUST00000129737.1
Tenm4
teneurin transmembrane protein 4
chr11_+_97415527 1.125 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr19_+_44989073 1.120 ENSMUST00000026225.8
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr2_+_25054355 1.113 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
Nsmf



NMDA receptor synaptonuclear signaling and neuronal migration factor



chr1_-_21961581 1.109 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr2_+_25054396 1.092 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
Nsmf




NMDA receptor synaptonuclear signaling and neuronal migration factor




chr10_-_116473418 1.092 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr10_+_58813359 1.091 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr2_-_31845925 1.087 ENSMUST00000028188.7
Fibcd1
fibrinogen C domain containing 1
chr3_-_88950401 1.081 ENSMUST00000090938.4
Dap3
death associated protein 3
chr8_-_70234097 1.034 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr6_-_136173492 1.026 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr12_-_69372443 1.011 ENSMUST00000053451.1
Gm9887
predicted gene 9887
chr4_+_123183456 0.984 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 2.5 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.2 2.4 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 2.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 2.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 2.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 2.1 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.2 2.0 GO:0005513 detection of calcium ion(GO:0005513)
0.6 1.9 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.3 1.2 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.0 1.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.2 0.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.9 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 0.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 2.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.1 GO:0097440 apical dendrite(GO:0097440)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.2 0.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.1 0.6 GO:0097361 CIA complex(GO:0097361)
0.1 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 0.5 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.4 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.3 1.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.3 1.1 GO:0008061 chitin binding(GO:0008061)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 1.0 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)