Motif ID: Ep300
Z-value: 0.585
Transcription factors associated with Ep300:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Ep300 | ENSMUSG00000055024.6 | Ep300 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Ep300 | mm10_v2_chr15_+_81586206_81586250 | -0.81 | 4.2e-07 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.4 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.6 | 1.9 | GO:1900736 | regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) |
0.3 | 1.2 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
0.2 | 2.0 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.2 | 0.6 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
0.2 | 0.9 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
0.2 | 2.4 | GO:0035635 | entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535) |
0.2 | 0.7 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
0.2 | 2.2 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.2 | 2.1 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.1 | 0.6 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.1 | 0.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.1 | 0.5 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.1 | 2.3 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.1 | 0.7 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
0.1 | 0.6 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.1 | 1.0 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
0.1 | 0.3 | GO:1904154 | trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
0.1 | 0.4 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
0.1 | 0.7 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.1 | 0.4 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
0.1 | 0.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.1 | 0.5 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
0.1 | 0.3 | GO:0071105 | response to interleukin-11(GO:0071105) osteoclast fusion(GO:0072675) |
0.1 | 0.2 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
0.1 | 0.3 | GO:0090148 | membrane fission(GO:0090148) |
0.1 | 0.3 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.1 | 0.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
0.1 | 0.9 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
0.1 | 0.4 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.1 | 0.4 | GO:0001955 | blood vessel maturation(GO:0001955) |
0.1 | 0.4 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.1 | 0.5 | GO:1902969 | mitotic DNA replication(GO:1902969) |
0.0 | 0.1 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.0 | 0.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.1 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
0.0 | 0.1 | GO:0042732 | D-xylose metabolic process(GO:0042732) |
0.0 | 0.5 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.0 | 0.7 | GO:2000821 | regulation of grooming behavior(GO:2000821) |
0.0 | 0.1 | GO:0015960 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
0.0 | 0.3 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
0.0 | 0.6 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.3 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
0.0 | 0.2 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.0 | 0.2 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.0 | 0.6 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
0.0 | 0.1 | GO:0036166 | phenotypic switching(GO:0036166) |
0.0 | 0.6 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
0.0 | 0.3 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
0.0 | 0.8 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.0 | 0.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.2 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
0.0 | 0.2 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 0.3 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
0.0 | 0.6 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.3 | GO:0042182 | ketone catabolic process(GO:0042182) |
0.0 | 0.6 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 1.1 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
0.0 | 0.7 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.0 | 0.0 | GO:0002295 | T-helper cell lineage commitment(GO:0002295) interleukin-4-mediated signaling pathway(GO:0035771) |
0.0 | 0.1 | GO:0051189 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.0 | 0.1 | GO:0070589 | cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554) |
0.0 | 0.1 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
0.0 | 0.2 | GO:1901250 | regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
0.0 | 0.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.3 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.9 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
0.0 | 0.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.0 | 2.5 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.0 | 0.6 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.0 | 0.1 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.0 | 0.3 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.0 | 0.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 0.4 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
0.0 | 0.2 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
0.0 | 0.0 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
0.0 | 0.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 1.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 2.1 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
0.0 | 0.5 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 0.1 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.0 | 0.3 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.0 | 0.4 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
0.0 | 0.2 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
0.0 | 0.4 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
0.0 | 0.7 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
0.0 | 0.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
0.0 | 0.2 | GO:0048557 | embryonic digestive tract morphogenesis(GO:0048557) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.4 | GO:0032584 | growth cone membrane(GO:0032584) |
0.2 | 0.5 | GO:0043512 | inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512) |
0.2 | 0.8 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.1 | 0.6 | GO:0097361 | CIA complex(GO:0097361) |
0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
0.1 | 1.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 1.0 | GO:0043083 | synaptic cleft(GO:0043083) |
0.1 | 0.3 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.1 | 0.6 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.1 | 2.4 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.1 | 2.1 | GO:0097440 | apical dendrite(GO:0097440) |
0.1 | 0.2 | GO:1990393 | 3M complex(GO:1990393) |
0.1 | 0.6 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.6 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.0 | 2.2 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.5 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 4.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.3 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.0 | 0.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.2 | GO:0097255 | R2TP complex(GO:0097255) |
0.0 | 1.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.0 | 0.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.0 | 0.4 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.1 | GO:0031502 | dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502) |
0.0 | 2.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.3 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.0 | 0.5 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.0 | 0.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.7 | GO:0005776 | autophagosome(GO:0005776) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.4 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
0.3 | 0.3 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.3 | 1.7 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.3 | 1.1 | GO:0008061 | chitin binding(GO:0008061) |
0.2 | 0.7 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.2 | 0.5 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.2 | 0.6 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
0.1 | 0.4 | GO:0005118 | sevenless binding(GO:0005118) |
0.1 | 2.0 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.1 | 0.8 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.1 | 1.0 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.1 | 0.3 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
0.1 | 0.6 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.1 | 0.5 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.1 | 1.5 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.1 | 0.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.6 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.1 | 2.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 0.4 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.1 | 0.2 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
0.1 | 0.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
0.1 | 1.1 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.1 | 0.2 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.0 | 0.7 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.6 | GO:0042923 | neuropeptide binding(GO:0042923) |
0.0 | 0.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.0 | 0.4 | GO:0034711 | inhibin binding(GO:0034711) |
0.0 | 0.7 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.6 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
0.0 | 1.5 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.1 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
0.0 | 0.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 0.4 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.0 | 0.1 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.0 | 0.4 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.0 | 0.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.5 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.9 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 1.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 1.3 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.4 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
0.0 | 2.2 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.6 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.2 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
0.0 | 0.3 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.0 | 0.2 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.5 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.1 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.0 | 1.0 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) |
0.0 | 0.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.0 | 0.8 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 2.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.2 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.0 | 0.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 1.9 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.0 | 0.3 | GO:0070403 | NAD+ binding(GO:0070403) |
0.0 | 0.1 | GO:0035473 | lipase binding(GO:0035473) |
0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.0 | 0.1 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 1.2 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 1.2 | GO:0008565 | protein transporter activity(GO:0008565) |