Motif ID: Epas1_Bcl3

Z-value: 2.056

Transcription factors associated with Epas1_Bcl3:

Gene SymbolEntrez IDGene Name
Bcl3 ENSMUSG00000053175.10 Bcl3
Epas1 ENSMUSG00000024140.9 Epas1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Epas1mm10_v2_chr17_+_86753900_867539140.413.9e-02Click!


Activity profile for motif Epas1_Bcl3.

activity profile for motif Epas1_Bcl3


Sorted Z-values histogram for motif Epas1_Bcl3

Sorted Z-values for motif Epas1_Bcl3



Network of associatons between targets according to the STRING database.



First level regulatory network of Epas1_Bcl3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_127725392 11.978 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr14_-_60177482 10.713 ENSMUST00000140924.1
 Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr17_+_48932368 10.095 ENSMUST00000046254.2
 Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr4_+_48045144 9.119 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr12_-_14152038 7.798 ENSMUST00000020926.6
 Fam84a
family with sequence similarity 84, member A
chr2_-_113217051 7.064 ENSMUST00000080673.5
 Ryr3
ryanodine receptor 3
chr4_+_130913120 6.755 ENSMUST00000151698.1
 Laptm5
lysosomal-associated protein transmembrane 5
chr9_-_29963112 6.752 ENSMUST00000075069.4
 Ntm
neurotrimin
chr4_+_130913264 6.426 ENSMUST00000156225.1
ENSMUST00000156742.1
 Laptm5

lysosomal-associated protein transmembrane 5

chr19_+_23758819 6.118 ENSMUST00000025830.7
 Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr4_+_123183722 6.070 ENSMUST00000152194.1
 Hpcal4
hippocalcin-like 4
chr9_-_40346290 6.052 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr6_-_84593810 6.037 ENSMUST00000077705.3
ENSMUST00000168003.2
 Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

chr7_-_27446599 5.831 ENSMUST00000011895.7
 Sptbn4
spectrin beta, non-erythrocytic 4
chr3_-_80802789 5.688 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr17_+_86167777 5.641 ENSMUST00000097275.2
 Prkce
protein kinase C, epsilon
chr4_-_46991842 5.201 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr18_-_25753852 4.910 ENSMUST00000025117.6
ENSMUST00000115816.2
 Celf4

CUGBP, Elav-like family member 4

chr19_+_8664005 4.844 ENSMUST00000035444.3
ENSMUST00000163785.1
 Chrm1

cholinergic receptor, muscarinic 1, CNS

chr8_-_48555846 4.746 ENSMUST00000110345.1
ENSMUST00000110343.1
 Tenm3

teneurin transmembrane protein 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 147 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 14.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 12.7 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
2.0 12.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
3.0 9.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.5 8.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
1.3 7.8 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.5 7.8 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.3 6.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 6.8 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
1.2 6.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 6.2 GO:0010977 negative regulation of neuron projection development(GO:0010977)
2.0 6.0 GO:0098528 terpenoid catabolic process(GO:0016115) skeletal muscle fiber differentiation(GO:0098528)
1.0 5.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.4 5.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.7 5.3 GO:0097264 self proteolysis(GO:0097264)
0.2 5.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.9 5.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 5.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 4.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 4.8 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 13.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 11.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.5 10.5 GO:0032279 asymmetric synapse(GO:0032279)
0.1 9.9 GO:0008021 synaptic vesicle(GO:0008021)
2.6 7.8 GO:0043512 inhibin A complex(GO:0043512)
1.4 7.1 GO:0030314 junctional membrane complex(GO:0030314)
0.1 6.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 6.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 6.2 GO:0031143 pseudopodium(GO:0031143)
1.0 5.8 GO:0008091 spectrin(GO:0008091)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
1.0 5.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 4.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 4.4 GO:0030027 lamellipodium(GO:0030027)
0.2 4.0 GO:0031430 M band(GO:0031430)
0.1 3.9 GO:0055038 recycling endosome membrane(GO:0055038)
1.3 3.8 GO:0071953 elastic fiber(GO:0071953)
0.1 3.7 GO:0033268 node of Ranvier(GO:0033268)
0.0 3.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 14.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 11.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 9.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 9.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 8.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.9 7.8 GO:0034711 inhibin binding(GO:0034711)
2.4 7.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.4 7.0 GO:0001223 transcription coactivator binding(GO:0001223)
1.1 6.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 6.7 GO:0005096 GTPase activator activity(GO:0005096)
2.1 6.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.7 6.0 GO:0001972 retinoic acid binding(GO:0001972)
1.4 5.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 5.4 GO:0030506 ankyrin binding(GO:0030506)
0.9 5.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.9 5.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 5.1 GO:0005272 sodium channel activity(GO:0005272)
0.4 4.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 3.9 GO:0045296 cadherin binding(GO:0045296)
0.3 3.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)