Motif ID: Erg

Z-value: 1.351


Transcription factors associated with Erg:

Gene SymbolEntrez IDGene Name
Erg ENSMUSG00000040732.12 Erg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ergmm10_v2_chr16_-_95459245_954593840.019.7e-01Click!


Activity profile for motif Erg.

activity profile for motif Erg


Sorted Z-values histogram for motif Erg

Sorted Z-values for motif Erg



Network of associatons between targets according to the STRING database.



First level regulatory network of Erg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 7.139 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_+_30078584 5.744 ENSMUST00000045246.7
 Pkn3
protein kinase N3
chr10_-_58675631 3.703 ENSMUST00000003312.4
 Edar
ectodysplasin-A receptor
chr9_-_54661870 3.630 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_-_79977782 3.100 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr9_-_54661666 3.098 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr6_-_72390659 2.873 ENSMUST00000059983.9
 Vamp8
vesicle-associated membrane protein 8
chr2_-_101883010 2.815 ENSMUST00000154525.1
 Prr5l
proline rich 5 like
chr11_-_101785252 2.701 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr9_+_91368970 2.530 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr5_+_75152274 2.517 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr2_-_101797650 2.509 ENSMUST00000141814.1
ENSMUST00000171088.1
ENSMUST00000043845.7
 Prr5l


proline rich 5 like


chr12_+_75308308 2.460 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr6_+_134035691 2.436 ENSMUST00000081028.6
ENSMUST00000111963.1
 Etv6

ets variant gene 6 (TEL oncogene)

chr12_-_56536895 2.428 ENSMUST00000001536.8
 Nkx2-1
NK2 homeobox 1
chr2_+_103970221 2.398 ENSMUST00000111140.2
ENSMUST00000111139.2
 Lmo2

LIM domain only 2

chr4_-_43523388 2.384 ENSMUST00000107913.3
ENSMUST00000030184.5
 Tpm2

tropomyosin 2, beta

chr1_+_189728264 2.357 ENSMUST00000097442.2
 Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr12_+_79029150 2.356 ENSMUST00000039928.5
 Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr10_+_26229707 2.351 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 228 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 7.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 7.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.3 6.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.0 5.7 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
1.8 5.3 GO:0038203 TORC2 signaling(GO:0038203)
0.6 4.8 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.4 4.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.8 4.2 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.2 4.0 GO:0043486 histone exchange(GO:0043486)
1.3 3.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.4 3.7 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2 3.2 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.1 3.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.7 3.0 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.4 3.0 GO:0007296 vitellogenesis(GO:0007296)
0.4 3.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 3.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.6 2.9 GO:2001204 regulation of osteoclast development(GO:2001204)
0.6 2.8 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.5 2.8 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 7.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 7.3 GO:0005730 nucleolus(GO:0005730)
0.0 6.1 GO:0000790 nuclear chromatin(GO:0000790)
0.5 5.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.6 5.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 5.3 GO:0031932 TORC2 complex(GO:0031932)
0.2 4.9 GO:0000242 pericentriolar material(GO:0000242)
1.0 3.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 3.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 3.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 3.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.9 GO:0005884 actin filament(GO:0005884)
0.1 2.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.7 GO:0045177 apical part of cell(GO:0045177)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 150 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 10.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.6 6.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 6.7 GO:0070888 E-box binding(GO:0070888)
0.1 6.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 6.4 GO:0051015 actin filament binding(GO:0051015)
0.0 6.2 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.3 5.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 5.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 5.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.7 4.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.8 3.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 3.7 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 3.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 3.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.4 2.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 2.9 GO:0051879 Hsp90 protein binding(GO:0051879)