Motif ID: Ets1

Z-value: 0.646


Transcription factors associated with Ets1:

Gene SymbolEntrez IDGene Name
Ets1 ENSMUSG00000032035.9 Ets1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets1mm10_v2_chr9_+_32696005_326961210.212.9e-01Click!


Activity profile for motif Ets1.

activity profile for motif Ets1


Sorted Z-values histogram for motif Ets1

Sorted Z-values for motif Ets1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5725639 3.497 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr15_-_66969616 3.414 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr6_+_5725812 2.820 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr15_-_66812593 1.824 ENSMUST00000100572.3
 Sla
src-like adaptor
chr7_+_44850393 1.622 ENSMUST00000136232.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr2_-_156312470 1.594 ENSMUST00000079125.6
 Scand1
SCAN domain-containing 1
chr8_-_71723308 1.480 ENSMUST00000125092.1
 Fcho1
FCH domain only 1
chr2_-_156392829 1.309 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr1_-_56969827 1.281 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr18_-_34931931 1.177 ENSMUST00000180351.1
 Etf1
eukaryotic translation termination factor 1
chr10_+_3366125 1.132 ENSMUST00000043374.5
 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr6_-_115994953 1.022 ENSMUST00000015511.8
 Plxnd1
plexin D1
chr7_-_127876777 1.008 ENSMUST00000106262.1
ENSMUST00000106263.1
ENSMUST00000054415.5
 Zfp668


zinc finger protein 668


chr1_-_56969864 0.992 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr7_+_24907618 0.985 ENSMUST00000151121.1
 Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr3_-_89245159 0.970 ENSMUST00000090924.6
 Trim46
tripartite motif-containing 46
chr10_-_18023229 0.964 ENSMUST00000020002.7
 Abracl
ABRA C-terminal like
chr5_+_117133567 0.934 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
 Taok3


TAO kinase 3


chr3_-_89245005 0.934 ENSMUST00000107464.1
 Trim46
tripartite motif-containing 46
chr7_-_4546567 0.933 ENSMUST00000065957.5
 Syt5
synaptotagmin V

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 313 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.7 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.1 2.6 GO:0060074 synapse maturation(GO:0060074)
0.1 2.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 2.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.3 2.2 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 2.0 GO:0002076 osteoblast development(GO:0002076)
0.4 1.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.4 1.7 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 1.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 1.5 GO:0019086 late viral transcription(GO:0019086)
0.1 1.3 GO:0006266 DNA ligation(GO:0006266)
0.1 1.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 1.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.2 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.0 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.0 GO:0071569 protein ufmylation(GO:0071569)
0.3 0.9 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.3 0.9 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 141 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 3.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 3.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.1 GO:0030018 Z disc(GO:0030018)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 2.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.0 GO:0031931 TORC1 complex(GO:0031931)
0.4 1.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4 1.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.3 GO:0071439 clathrin complex(GO:0071439)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.2 GO:1990745 EARP complex(GO:1990745)
0.0 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.1 1.1 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 175 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 6.3 GO:0045503 dynein light chain binding(GO:0045503)
0.1 3.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 2.6 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1 2.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 2.1 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 1.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.8 GO:0008565 protein transporter activity(GO:0008565)
0.2 1.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 1.7 GO:0030276 clathrin binding(GO:0030276)
0.1 1.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)