Motif ID: Etv1_Etv5_Gabpa

Z-value: 1.943

Transcription factors associated with Etv1_Etv5_Gabpa:

Gene SymbolEntrez IDGene Name
Etv1 ENSMUSG00000004151.10 Etv1
Etv5 ENSMUSG00000013089.9 Etv5
Gabpa ENSMUSG00000008976.10 Gabpa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv5mm10_v2_chr16_-_22439719_22439733-0.611.0e-03Click!
Etv1mm10_v2_chr12_+_38783503_38783527-0.311.2e-01Click!
Gabpamm10_v2_chr16_+_84834901_848349410.144.9e-01Click!


Activity profile for motif Etv1_Etv5_Gabpa.

activity profile for motif Etv1_Etv5_Gabpa


Sorted Z-values histogram for motif Etv1_Etv5_Gabpa

Sorted Z-values for motif Etv1_Etv5_Gabpa



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv1_Etv5_Gabpa

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_94653964 8.497 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr16_-_22161450 7.584 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_5845243 7.276 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr7_-_122132844 6.477 ENSMUST00000106469.1
ENSMUST00000063587.6
ENSMUST00000106468.1
ENSMUST00000130149.1
ENSMUST00000098068.3
 Palb2




partner and localizer of BRCA2




chr6_+_4755327 6.314 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr7_-_127042420 6.030 ENSMUST00000032915.6
 Kif22
kinesin family member 22
chr2_+_105682463 5.888 ENSMUST00000140173.1
ENSMUST00000135412.1
ENSMUST00000138365.1
ENSMUST00000145744.1
 Pax6



paired box gene 6



chr2_+_5845017 5.813 ENSMUST00000026927.3
ENSMUST00000179748.1
 Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr4_-_45320580 5.562 ENSMUST00000030003.3
 Exosc3
exosome component 3
chr16_-_18811972 5.509 ENSMUST00000000028.7
ENSMUST00000115585.1
 Cdc45

cell division cycle 45

chr19_+_6084983 5.369 ENSMUST00000025704.2
 Cdca5
cell division cycle associated 5
chr9_-_57836706 5.298 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
 Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr1_-_128102412 5.277 ENSMUST00000112538.1
ENSMUST00000086614.5
 Zranb3

zinc finger, RAN-binding domain containing 3

chr16_+_48994185 5.158 ENSMUST00000117994.1
ENSMUST00000048374.5
 C330027C09Rik

RIKEN cDNA C330027C09 gene

chr19_-_40271506 5.090 ENSMUST00000068439.6
 Pdlim1
PDZ and LIM domain 1 (elfin)
chr4_+_124714776 5.023 ENSMUST00000030734.4
 Sf3a3
splicing factor 3a, subunit 3
chr5_+_140331860 5.005 ENSMUST00000071881.3
ENSMUST00000050205.5
ENSMUST00000110827.1
 Nudt1


nudix (nucleoside diphosphate linked moiety X)-type motif 1


chr1_+_187215501 4.899 ENSMUST00000097443.3
ENSMUST00000065573.7
ENSMUST00000110943.2
ENSMUST00000044812.5
 Gpatch2



G patch domain containing 2



chr2_-_91649751 4.859 ENSMUST00000099714.3
 Zfp408
zinc finger protein 408
chr14_-_31494992 4.759 ENSMUST00000055303.3
 Mettl6
methyltransferase like 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 657 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 61.2 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.6 23.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.6 23.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 20.3 GO:0006413 translational initiation(GO:0006413)
0.6 17.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.9 16.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 16.4 GO:0051028 mRNA transport(GO:0051028)
0.1 15.8 GO:0008380 RNA splicing(GO:0008380)
0.9 13.3 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.6 12.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
3.1 12.5 GO:0030576 Cajal body organization(GO:0030576)
0.4 11.5 GO:0030488 tRNA methylation(GO:0030488)
0.6 10.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
1.0 10.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 10.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.4 9.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
1.2 9.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 9.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 8.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.5 8.4 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 304 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 68.9 GO:0005730 nucleolus(GO:0005730)
0.5 44.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.6 41.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.6 30.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
1.7 20.1 GO:0005687 U4 snRNP(GO:0005687)
0.6 20.0 GO:0015030 Cajal body(GO:0015030)
0.0 14.9 GO:0031981 nuclear lumen(GO:0031981)
0.5 14.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.4 14.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 13.9 GO:0005667 transcription factor complex(GO:0005667)
0.4 13.5 GO:0035371 microtubule plus-end(GO:0035371)
0.7 12.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 12.0 GO:0005643 nuclear pore(GO:0005643)
0.1 11.9 GO:0005681 spliceosomal complex(GO:0005681)
0.2 11.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 10.8 GO:0030880 RNA polymerase complex(GO:0030880)
0.3 10.1 GO:0030684 preribosome(GO:0030684)
0.9 9.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.6 9.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.5 9.9 GO:0033276 transcription factor TFTC complex(GO:0033276)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 390 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 83.1 GO:0044822 poly(A) RNA binding(GO:0044822)
0.3 50.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 28.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 24.8 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.4 17.2 GO:0019843 rRNA binding(GO:0019843)
0.6 15.1 GO:0030515 snoRNA binding(GO:0030515)
1.8 14.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.9 14.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 14.1 GO:0003723 RNA binding(GO:0003723)
0.6 13.3 GO:0017025 TBP-class protein binding(GO:0017025)
4.2 12.5 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
1.5 12.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 11.4 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.2 11.4 GO:0000049 tRNA binding(GO:0000049)
1.5 10.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.7 9.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 9.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 9.2 GO:0004519 endonuclease activity(GO:0004519)
0.4 9.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
1.3 8.9 GO:1990446 U1 snRNP binding(GO:1990446)