Motif ID: Etv6

Z-value: 1.155


Transcription factors associated with Etv6:

Gene SymbolEntrez IDGene Name
Etv6 ENSMUSG00000030199.10 Etv6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv6mm10_v2_chr6_+_134035691_134035717-0.193.5e-01Click!


Activity profile for motif Etv6.

activity profile for motif Etv6


Sorted Z-values histogram for motif Etv6

Sorted Z-values for motif Etv6



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_35135463 1.262 ENSMUST00000173535.1
ENSMUST00000173952.1
 Bag6

BCL2-associated athanogene 6

chr7_-_4546567 1.254 ENSMUST00000065957.5
 Syt5
synaptotagmin V
chr4_+_118409331 1.130 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
 Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr13_+_20090538 1.125 ENSMUST00000072519.5
 Elmo1
engulfment and cell motility 1
chr13_+_20090500 1.062 ENSMUST00000165249.2
 Elmo1
engulfment and cell motility 1
chr3_-_94886945 1.042 ENSMUST00000005923.6
 Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr17_+_35135695 1.034 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
 Bag6


BCL2-associated athanogene 6


chr6_-_120822680 1.008 ENSMUST00000019354.8
 Atp6v1e1
ATPase, H+ transporting, lysosomal V1 subunit E1
chr3_+_95217417 0.991 ENSMUST00000181819.1
 Gm16740
predicted gene, 16740
chr2_+_180257373 0.982 ENSMUST00000059080.6
 Rps21
ribosomal protein S21
chr15_+_58933774 0.962 ENSMUST00000022980.3
 Ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr9_-_21149894 0.946 ENSMUST00000019615.9
 Cdc37
cell division cycle 37
chr7_-_46919915 0.942 ENSMUST00000143413.1
ENSMUST00000014546.8
 Tsg101

tumor susceptibility gene 101

chr3_-_89764581 0.929 ENSMUST00000029562.3
 Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr17_+_35135174 0.927 ENSMUST00000166426.2
ENSMUST00000025250.7
 Bag6

BCL2-associated athanogene 6

chr11_-_120457936 0.926 ENSMUST00000137632.1
ENSMUST00000044007.2
 Oxld1

oxidoreductase like domain containing 1

chr5_-_31220491 0.917 ENSMUST00000031032.7
 Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr4_+_44012661 0.916 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
 Clta


clathrin, light polypeptide (Lca)


chr18_+_62548911 0.911 ENSMUST00000055725.4
ENSMUST00000162365.1
 Spink10

serine peptidase inhibitor, Kazal type 10

chr19_-_6084873 0.883 ENSMUST00000160977.1
ENSMUST00000159859.1
 Zfpl1

zinc finger like protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.1 GO:0006412 translation(GO:0006412)
0.1 5.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.5 4.0 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 3.0 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 2.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.1 GO:0006465 signal peptide processing(GO:0006465)
0.2 1.9 GO:0071569 protein ufmylation(GO:0071569)
0.0 1.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 1.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 1.3 GO:0032543 mitochondrial translation(GO:0032543)
0.1 1.2 GO:0031053 production of siRNA involved in RNA interference(GO:0030422) primary miRNA processing(GO:0031053)
0.0 1.1 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.3 1.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 1.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.0 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.4 0.9 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.3 0.9 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 0.9 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.6 4.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 2.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.8 GO:0071439 clathrin complex(GO:0071439)
0.1 1.7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 1.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.4 1.3 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.4 1.2 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 1.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.1 GO:0000243 commitment complex(GO:0000243)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.3 0.9 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 0.9 GO:0070436 Grb2-EGFR complex(GO:0070436)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 4.0 GO:0070628 proteasome binding(GO:0070628)
0.0 2.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.3 1.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 1.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 1.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 1.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 1.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.6 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.5 GO:0031386 protein tag(GO:0031386)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.5 GO:0043022 ribosome binding(GO:0043022)
0.0 1.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.3 1.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)