Motif ID: Figla

Z-value: 0.642


Transcription factors associated with Figla:

Gene SymbolEntrez IDGene Name
Figla ENSMUSG00000030001.3 Figla



Activity profile for motif Figla.

activity profile for motif Figla


Sorted Z-values histogram for motif Figla

Sorted Z-values for motif Figla



Network of associatons between targets according to the STRING database.



First level regulatory network of Figla

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_99864476 3.614 ENSMUST00000092694.3
 Gm11559
predicted gene 11559
chr2_-_122611238 3.089 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr7_-_144939823 2.318 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr12_+_109459843 2.196 ENSMUST00000173812.1
 Dlk1
delta-like 1 homolog (Drosophila)
chr12_-_40038025 1.945 ENSMUST00000101472.3
 Arl4a
ADP-ribosylation factor-like 4A
chr7_+_19094594 1.794 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr14_-_20181773 1.711 ENSMUST00000024011.8
 Kcnk5
potassium channel, subfamily K, member 5
chr5_+_123749696 1.676 ENSMUST00000031366.7
 Kntc1
kinetochore associated 1
chr1_-_128102412 1.647 ENSMUST00000112538.1
ENSMUST00000086614.5
 Zranb3

zinc finger, RAN-binding domain containing 3

chr10_-_127341583 1.592 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr10_+_26229707 1.579 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr12_-_40037387 1.560 ENSMUST00000146905.1
 Arl4a
ADP-ribosylation factor-like 4A
chr15_+_25622525 1.558 ENSMUST00000110457.1
ENSMUST00000137601.1
 Myo10

myosin X

chr1_-_128103016 1.451 ENSMUST00000097597.2
 Zranb3
zinc finger, RAN-binding domain containing 3
chr2_+_164769892 1.354 ENSMUST00000088248.6
ENSMUST00000001439.6
 Ube2c

ubiquitin-conjugating enzyme E2C

chr6_+_29694204 1.311 ENSMUST00000046750.7
ENSMUST00000115250.3
 Tspan33

tetraspanin 33

chr2_+_168081004 1.301 ENSMUST00000052125.6
 Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr14_+_27039001 1.268 ENSMUST00000035336.3
 Il17rd
interleukin 17 receptor D
chr11_+_117809653 1.250 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
 Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr11_-_82871133 1.234 ENSMUST00000071152.7
ENSMUST00000108173.3
 Rffl

ring finger and FYVE like domain containing protein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.8 GO:0050873 brown fat cell differentiation(GO:0050873)
1.0 3.1 GO:0036292 DNA rewinding(GO:0036292)
1.0 3.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.7 2.8 GO:0060032 notochord regression(GO:0060032)
0.3 2.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 2.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.8 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 1.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 1.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 1.4 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 1.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.3 1.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 1.2 GO:0051311 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
0.3 1.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 1.1 GO:0071205 clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205)
0.3 1.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.2 1.0 GO:0035063 nuclear speck organization(GO:0035063)
0.2 1.0 GO:0032439 endosome localization(GO:0032439)
0.1 1.0 GO:0030035 microspike assembly(GO:0030035)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 GO:0043596 nuclear replication fork(GO:0043596)
0.0 2.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 2.8 GO:0097542 ciliary tip(GO:0097542)
0.1 2.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.6 1.7 GO:1990423 RZZ complex(GO:1990423)
0.1 1.7 GO:0030673 axolemma(GO:0030673)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.5 GO:0016607 nuclear speck(GO:0016607)
0.2 1.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.2 GO:0072687 meiotic spindle(GO:0072687)
0.3 1.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.2 1.0 GO:0045179 apical cortex(GO:0045179)
0.1 1.0 GO:0042627 chylomicron(GO:0042627)
0.2 0.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.7 GO:0008537 proteasome activator complex(GO:0008537)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 3.2 GO:0003924 GTPase activity(GO:0003924)
0.3 3.1 GO:0036310 annealing helicase activity(GO:0036310)
0.1 3.1 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 2.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 1.5 GO:0002039 p53 binding(GO:0002039)
0.4 1.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 1.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.0 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 0.9 GO:0005113 patched binding(GO:0005113)
0.2 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.9 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.2 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)