Motif ID: Fli1
Z-value: 1.410
Transcription factors associated with Fli1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Fli1 | ENSMUSG00000016087.7 | Fli1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Fli1 | mm10_v2_chr9_-_32541589_32541602 | 0.22 | 2.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 33.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
1.2 | 3.5 | GO:0071336 | lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
1.1 | 4.6 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
1.0 | 11.4 | GO:0032096 | negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099) |
0.9 | 4.5 | GO:2000587 | regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
0.7 | 8.2 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.7 | 4.4 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.7 | 7.2 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
0.6 | 3.0 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.5 | 1.6 | GO:0002586 | positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499) |
0.4 | 4.0 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.4 | 8.4 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
0.3 | 4.5 | GO:0043589 | skin morphogenesis(GO:0043589) |
0.3 | 1.8 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.2 | 1.0 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
0.2 | 0.9 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
0.2 | 1.2 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.2 | 4.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.2 | 0.9 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
0.2 | 8.8 | GO:0033014 | porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014) |
0.2 | 0.8 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) |
0.2 | 1.2 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
0.2 | 0.8 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
0.2 | 2.2 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.2 | 0.5 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
0.1 | 0.7 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
0.1 | 0.8 | GO:0032596 | protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227) |
0.1 | 8.8 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.1 | 2.5 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.1 | 3.3 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.1 | 0.4 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.1 | 7.5 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.1 | 10.2 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
0.1 | 0.8 | GO:0042940 | D-amino acid transport(GO:0042940) |
0.1 | 3.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.1 | 1.0 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
0.1 | 0.8 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
0.1 | 0.2 | GO:0072553 | terminal button organization(GO:0072553) |
0.1 | 1.1 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.1 | 1.3 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.1 | 0.2 | GO:0034287 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
0.1 | 0.4 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.1 | 0.6 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.1 | 2.7 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.4 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
0.0 | 1.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.2 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.0 | 0.1 | GO:0001866 | NK T cell proliferation(GO:0001866) regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) |
0.0 | 0.2 | GO:0040016 | embryonic cleavage(GO:0040016) |
0.0 | 2.2 | GO:0006821 | chloride transport(GO:0006821) |
0.0 | 0.3 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
0.0 | 2.5 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
0.0 | 0.9 | GO:0043388 | positive regulation of DNA binding(GO:0043388) |
0.0 | 0.1 | GO:0036506 | maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.0 | 0.1 | GO:0015862 | uridine transport(GO:0015862) |
0.0 | 1.1 | GO:0008593 | regulation of Notch signaling pathway(GO:0008593) |
0.0 | 0.9 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.0 | 1.0 | GO:0007631 | feeding behavior(GO:0007631) |
0.0 | 0.8 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 0.5 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.5 | GO:0005584 | collagen type I trimer(GO:0005584) |
1.3 | 7.9 | GO:0044308 | axonal spine(GO:0044308) |
0.9 | 17.0 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.7 | 10.2 | GO:0044292 | dendrite terminus(GO:0044292) |
0.4 | 1.2 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
0.3 | 0.9 | GO:0031983 | vesicle lumen(GO:0031983) |
0.2 | 4.0 | GO:0031527 | filopodium membrane(GO:0031527) |
0.2 | 3.0 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.2 | 3.3 | GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178) |
0.2 | 0.8 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
0.2 | 8.8 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.1 | 1.4 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.1 | 6.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 2.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 0.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.1 | 4.9 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
0.1 | 2.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.2 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.0 | 1.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 37.9 | GO:0031410 | cytoplasmic vesicle(GO:0031410) |
0.0 | 0.2 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 0.8 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 4.4 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.1 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.0 | 1.8 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 1.3 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.8 | 34.6 | GO:0032051 | clathrin light chain binding(GO:0032051) |
1.1 | 7.9 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.9 | 3.5 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.7 | 4.0 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.6 | 10.2 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.6 | 17.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.4 | 1.6 | GO:0070891 | peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891) |
0.3 | 3.0 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.3 | 0.9 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.3 | 4.5 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.3 | 3.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.2 | 2.4 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.2 | 0.9 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.2 | 1.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.2 | 4.5 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.2 | 6.9 | GO:0045296 | cadherin binding(GO:0045296) |
0.1 | 2.5 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.1 | 8.4 | GO:0019003 | GDP binding(GO:0019003) |
0.1 | 1.1 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 4.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 4.4 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.1 | 0.2 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
0.1 | 0.8 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.1 | 9.9 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.1 | 2.5 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.1 | 5.5 | GO:0008083 | growth factor activity(GO:0008083) |
0.1 | 0.8 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.1 | 0.4 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 1.2 | GO:0043236 | laminin binding(GO:0043236) |
0.0 | 0.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.0 | 1.1 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.5 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
0.0 | 0.2 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) |
0.0 | 4.0 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
0.0 | 0.3 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.3 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.0 | 0.6 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 2.2 | GO:0019210 | protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210) |
0.0 | 0.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 1.8 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 0.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.5 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 1.0 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
0.0 | 0.5 | GO:0016831 | carboxy-lyase activity(GO:0016831) |