Motif ID: Fos

Z-value: 0.910


Transcription factors associated with Fos:

Gene SymbolEntrez IDGene Name
Fos ENSMUSG00000021250.7 Fos

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_85473896-0.281.7e-01Click!


Activity profile for motif Fos.

activity profile for motif Fos


Sorted Z-values histogram for motif Fos

Sorted Z-values for motif Fos



Network of associatons between targets according to the STRING database.



First level regulatory network of Fos

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_82910863 5.098 ENSMUST00000171238.1
 Zfp516
zinc finger protein 516
chr13_+_15463837 4.484 ENSMUST00000110510.3
 Gli3
GLI-Kruppel family member GLI3
chr2_+_20737306 4.429 ENSMUST00000114606.1
ENSMUST00000114608.1
 Etl4

enhancer trap locus 4

chr7_-_126799163 4.044 ENSMUST00000032934.5
 Aldoa
aldolase A, fructose-bisphosphate
chr6_+_53573364 3.817 ENSMUST00000047450.7
 Creb5
cAMP responsive element binding protein 5
chr7_+_19083842 3.608 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
 Dmpk



dystrophia myotonica-protein kinase



chr7_-_126799134 3.543 ENSMUST00000087566.4
 Aldoa
aldolase A, fructose-bisphosphate
chr2_+_30078584 3.521 ENSMUST00000045246.7
 Pkn3
protein kinase N3
chrX_-_143827391 3.079 ENSMUST00000087316.5
 Capn6
calpain 6
chr10_+_88091070 2.792 ENSMUST00000048621.7
 Pmch
pro-melanin-concentrating hormone
chr2_+_13573927 2.739 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr16_-_44558864 2.651 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr5_+_42067960 2.645 ENSMUST00000087332.4
 Gm16223
predicted gene 16223
chr17_+_43952999 2.634 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr10_-_42583628 2.511 ENSMUST00000019938.4
 Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr8_-_61591130 2.409 ENSMUST00000135439.1
ENSMUST00000121200.1
 Palld

palladin, cytoskeletal associated protein

chr3_+_116878227 2.401 ENSMUST00000040260.6
 Frrs1
ferric-chelate reductase 1
chr16_-_44558879 2.376 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr1_+_107511489 2.283 ENSMUST00000064916.2
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr17_+_43953191 2.234 ENSMUST00000044792.4
 Rcan2
regulator of calcineurin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 126 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 7.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 5.1 GO:0009409 response to cold(GO:0009409)
0.2 5.0 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 4.9 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.5 4.5 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.0 4.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 4.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 3.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.9 2.8 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.3 2.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.5 2.7 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.5 2.5 GO:0021764 amygdala development(GO:0021764)
0.1 2.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 2.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.8 2.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 2.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.5 2.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 2.2 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.2 2.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 7.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 4.3 GO:0016592 mediator complex(GO:0016592)
0.2 3.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.1 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.1 GO:0005876 spindle microtubule(GO:0005876)
0.2 2.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.7 2.7 GO:0045098 type III intermediate filament(GO:0045098)
0.8 2.3 GO:1990047 spindle matrix(GO:1990047)
0.2 2.2 GO:0005915 zonula adherens(GO:0005915)
0.0 2.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.1 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.9 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0000786 nucleosome(GO:0000786)
0.2 1.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 1.3 GO:0008623 CHRAC(GO:0008623)
0.2 1.3 GO:0005827 polar microtubule(GO:0005827)
0.1 1.3 GO:0031597 cytosolic proteasome complex(GO:0031597)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.3 7.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 7.3 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 5.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.8 4.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 4.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 3.8 GO:0017166 vinculin binding(GO:0017166)
0.2 3.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 3.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 3.5 GO:0004697 protein kinase C activity(GO:0004697)
0.8 3.2 GO:1990254 keratin filament binding(GO:1990254)
0.1 3.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.8 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.1 2.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 2.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 2.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.4 2.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)