Motif ID: Fosb

Z-value: 0.329


Transcription factors associated with Fosb:

Gene SymbolEntrez IDGene Name
Fosb ENSMUSG00000003545.2 Fosb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_19310050-0.183.7e-01Click!


Activity profile for motif Fosb.

activity profile for motif Fosb


Sorted Z-values histogram for motif Fosb

Sorted Z-values for motif Fosb



Network of associatons between targets according to the STRING database.



First level regulatory network of Fosb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_167777467 0.432 ENSMUST00000139927.1
ENSMUST00000127441.1
 Gm14321

predicted gene 14321

chr10_-_64090265 0.396 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr2_+_118663235 0.394 ENSMUST00000099557.3
 Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr11_-_69666062 0.353 ENSMUST00000108654.2
ENSMUST00000018918.5
 Cd68

CD68 antigen

chr5_-_86676346 0.349 ENSMUST00000038448.6
 Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr8_+_36489191 0.348 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr11_-_102365111 0.343 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr16_+_78930940 0.335 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr9_+_104566677 0.319 ENSMUST00000157006.1
 Cpne4
copine IV
chr3_+_55461758 0.316 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr6_-_124769548 0.297 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
 Eno2


enolase 2, gamma neuronal


chr4_-_140774196 0.289 ENSMUST00000026381.6
 Padi4
peptidyl arginine deiminase, type IV
chr2_-_151632471 0.284 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
 Snph






syntaphilin






chr10_+_26078255 0.282 ENSMUST00000041011.3
 Gm9767
predicted gene 9767
chr18_+_61639542 0.276 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr11_-_84067063 0.263 ENSMUST00000108101.1
 Dusp14
dual specificity phosphatase 14
chr10_-_64090241 0.262 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr15_-_102257449 0.254 ENSMUST00000043172.8
 Rarg
retinoic acid receptor, gamma
chr10_-_86011833 0.245 ENSMUST00000105304.1
ENSMUST00000061699.5
 Bpifc

BPI fold containing family C

chr1_+_134560157 0.237 ENSMUST00000047714.7
 Kdm5b
lysine (K)-specific demethylase 5B
chr15_-_102257306 0.209 ENSMUST00000135466.1
 Rarg
retinoic acid receptor, gamma
chr16_+_17561885 0.197 ENSMUST00000171002.1
ENSMUST00000023441.4
 P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr1_+_134560190 0.196 ENSMUST00000112198.1
ENSMUST00000112197.1
 Kdm5b

lysine (K)-specific demethylase 5B

chr2_+_156475844 0.194 ENSMUST00000103135.1
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr14_+_27622433 0.183 ENSMUST00000090302.5
 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr7_-_45920830 0.178 ENSMUST00000164119.1
 Emp3
epithelial membrane protein 3
chr15_+_102503722 0.173 ENSMUST00000096145.4
 Gm10337
predicted gene 10337
chr2_-_18048784 0.162 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr17_+_46161021 0.150 ENSMUST00000024748.7
ENSMUST00000172170.1
 Gtpbp2

GTP binding protein 2

chr2_+_156475803 0.145 ENSMUST00000029155.8
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr1_+_120602405 0.141 ENSMUST00000079721.7
 En1
engrailed 1
chr16_-_4880284 0.139 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr11_-_100397740 0.137 ENSMUST00000001592.8
ENSMUST00000107403.1
 Jup

junction plakoglobin

chr10_+_116143881 0.133 ENSMUST00000105271.2
 Ptprr
protein tyrosine phosphatase, receptor type, R
chr8_-_8639363 0.131 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr9_-_109059216 0.130 ENSMUST00000112053.1
 Trex1
three prime repair exonuclease 1
chr18_+_82910863 0.127 ENSMUST00000171238.1
 Zfp516
zinc finger protein 516
chr11_-_96075581 0.124 ENSMUST00000107686.1
ENSMUST00000107684.1
 Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr15_-_76014318 0.122 ENSMUST00000060807.5
 Fam83h
family with sequence similarity 83, member H
chr9_-_109059711 0.118 ENSMUST00000061973.4
 Trex1
three prime repair exonuclease 1
chr7_-_29505447 0.118 ENSMUST00000183096.1
ENSMUST00000085809.4
 Sipa1l3

signal-induced proliferation-associated 1 like 3

chr19_+_5447692 0.116 ENSMUST00000025850.5
 Fosl1
fos-like antigen 1
chr7_+_30413744 0.114 ENSMUST00000032800.9
 Tyrobp
TYRO protein tyrosine kinase binding protein
chr1_-_171240055 0.109 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr13_+_30659999 0.100 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
 Dusp22


dual specificity phosphatase 22


chr11_+_80428598 0.099 ENSMUST00000173938.1
ENSMUST00000017572.7
 Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr3_+_116878227 0.089 ENSMUST00000040260.6
 Frrs1
ferric-chelate reductase 1
chr11_-_96075655 0.088 ENSMUST00000090541.5
 Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr17_-_35697971 0.086 ENSMUST00000146472.1
 Ddr1
discoidin domain receptor family, member 1
chr11_-_43747963 0.076 ENSMUST00000048578.2
ENSMUST00000109278.1
 Ttc1

tetratricopeptide repeat domain 1

chr9_-_119977250 0.074 ENSMUST00000035101.7
 Csrnp1
cysteine-serine-rich nuclear protein 1
chr7_-_133782721 0.069 ENSMUST00000063669.1
 Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr1_-_12991109 0.066 ENSMUST00000115403.2
ENSMUST00000115402.1
 Slco5a1

solute carrier organic anion transporter family, member 5A1

chr6_+_42349826 0.065 ENSMUST00000070635.6
 Zyx
zyxin
chr17_-_45592485 0.065 ENSMUST00000166119.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr2_+_143915273 0.064 ENSMUST00000103172.3
 Dstn
destrin
chr9_-_32541589 0.061 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr3_+_123267445 0.059 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr6_+_42350000 0.058 ENSMUST00000164375.1
 Zyx
zyxin
chrX_+_73675500 0.057 ENSMUST00000171398.1
 Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr16_+_20548577 0.054 ENSMUST00000003319.5
 Abcf3
ATP-binding cassette, sub-family F (GCN20), member 3
chr9_+_96258697 0.051 ENSMUST00000179416.1
 Tfdp2
transcription factor Dp 2
chr6_-_129533267 0.047 ENSMUST00000181594.1
 1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr6_+_86849488 0.046 ENSMUST00000089519.6
ENSMUST00000113668.1
 Aak1

AP2 associated kinase 1

chr3_-_88177671 0.044 ENSMUST00000181837.1
 1700113A16Rik
RIKEN cDNA 1700113A16 gene
chr14_-_55758458 0.042 ENSMUST00000001497.7
 Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr2_+_164948219 0.041 ENSMUST00000017881.2
 Mmp9
matrix metallopeptidase 9
chr9_+_122888471 0.040 ENSMUST00000063980.6
 Zkscan7
zinc finger with KRAB and SCAN domains 7
chr9_+_96259246 0.039 ENSMUST00000179065.1
ENSMUST00000165768.2
 Tfdp2

transcription factor Dp 2

chr7_-_100547620 0.036 ENSMUST00000064334.2
 D630004N19Rik
RIKEN cDNA D630004N19 gene
chr11_-_3914664 0.034 ENSMUST00000109995.1
ENSMUST00000051207.1
 Slc35e4

solute carrier family 35, member E4

chr12_-_85288419 0.033 ENSMUST00000121930.1
 Acyp1
acylphosphatase 1, erythrocyte (common) type
chr8_+_4226827 0.031 ENSMUST00000053035.6
 Lrrc8e
leucine rich repeat containing 8 family, member E
chr1_+_86064619 0.031 ENSMUST00000027432.8
 Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr7_-_4778141 0.025 ENSMUST00000094892.5
 Il11
interleukin 11
chr11_-_50210765 0.024 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
 Sqstm1


sequestosome 1


chr2_-_25224653 0.023 ENSMUST00000043584.4
 Tubb4b
tubulin, beta 4B class IVB
chr11_+_77801291 0.022 ENSMUST00000100794.3
 Myo18a
myosin XVIIIA
chr5_-_21785115 0.021 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
 Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr11_+_78188737 0.017 ENSMUST00000108322.2
 Rab34
RAB34, member of RAS oncogene family
chr2_+_30441831 0.017 ENSMUST00000131476.1
 Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr12_+_16810940 0.015 ENSMUST00000020908.7
 E2f6
E2F transcription factor 6
chr11_-_70015346 0.014 ENSMUST00000018718.7
ENSMUST00000102574.3
 Acadvl

acyl-Coenzyme A dehydrogenase, very long chain

chr7_-_127946725 0.012 ENSMUST00000118755.1
ENSMUST00000094026.3
 Prss36

protease, serine, 36

chr11_+_78188422 0.011 ENSMUST00000002128.7
ENSMUST00000150941.1
 Rab34

RAB34, member of RAS oncogene family

chr11_+_77801325 0.008 ENSMUST00000151373.2
ENSMUST00000172303.2
ENSMUST00000130305.2
ENSMUST00000164334.1
ENSMUST00000092884.4
 Myo18a




myosin XVIIIA




chr12_-_84194007 0.007 ENSMUST00000110294.1
 Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr14_+_80000292 0.006 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr13_-_113663670 0.004 ENSMUST00000054650.4
 Hspb3
heat shock protein 3
chr5_-_5265224 0.003 ENSMUST00000115450.1
 Cdk14
cyclin-dependent kinase 14
chr18_+_40258361 0.001 ENSMUST00000091927.4
 Kctd16
potassium channel tetramerisation domain containing 16
chr1_-_51915968 0.001 ENSMUST00000046390.7
 Myo1b
myosin IB
chr11_-_120630516 0.000 ENSMUST00000106181.1
 Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.4 GO:0034720 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) histone H3-K4 demethylation(GO:0034720) mammary duct terminal end bud growth(GO:0060763)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.7 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701) response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.0 GO:1900122 positive regulation of receptor binding(GO:1900122)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)