Motif ID: Foxa3

Z-value: 1.260


Transcription factors associated with Foxa3:

Gene SymbolEntrez IDGene Name
Foxa3 ENSMUSG00000040891.5 Foxa3



Activity profile for motif Foxa3.

activity profile for motif Foxa3


Sorted Z-values histogram for motif Foxa3

Sorted Z-values for motif Foxa3



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxa3

PNG image of the network

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Top targets:


Showing 1 to 20 of 163 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103813913 9.982 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr16_+_91269759 8.922 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr7_-_103827922 7.374 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr15_+_3270767 4.701 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr10_+_60106452 4.533 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr9_+_53850243 3.953 ENSMUST00000048485.5
 Sln
sarcolipin
chr1_+_17145357 3.757 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr11_+_78499087 3.673 ENSMUST00000017488.4
 Vtn
vitronectin
chr1_+_51289106 3.565 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr7_+_113765998 3.309 ENSMUST00000046687.9
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr3_-_87263518 3.293 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr17_+_70522083 3.249 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr8_-_84773381 3.190 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr11_-_26210553 2.855 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr4_+_42916647 2.842 ENSMUST00000132173.1
ENSMUST00000107975.1
 N28178

expressed sequence N28178

chr2_-_77519565 2.807 ENSMUST00000111830.2
 Zfp385b
zinc finger protein 385B
chr4_+_42922253 2.763 ENSMUST00000139100.1
 N28178
expressed sequence N28178
chr3_-_144202300 2.738 ENSMUST00000121796.1
ENSMUST00000121112.1
 Lmo4

LIM domain only 4

chr19_+_26623419 2.625 ENSMUST00000176584.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_112187766 2.522 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.8 GO:0070842 aggresome assembly(GO:0070842)
0.6 5.3 GO:0071420 cellular response to histamine(GO:0071420)
0.7 4.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.5 4.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 4.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 4.2 GO:0048663 neuron fate commitment(GO:0048663)
1.0 4.0 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.1 3.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.5 3.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.4 3.7 GO:0097421 liver regeneration(GO:0097421)
0.2 3.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 2.7 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.3 2.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 2.4 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 2.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.6 2.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.4 2.2 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.4 2.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.3 2.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 2.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.3 17.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 10.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 7.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 6.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 5.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 4.4 GO:0005901 caveola(GO:0005901)
0.2 4.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.7 3.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 3.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.6 GO:0071564 npBAF complex(GO:0071564)
0.3 2.4 GO:0097433 dense body(GO:0097433)
0.7 2.2 GO:0043512 inhibin A complex(GO:0043512)
0.0 2.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.9 GO:0043204 perikaryon(GO:0043204)
0.4 1.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 1.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 1.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.3 17.4 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.3 5.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 4.7 GO:0008430 selenium binding(GO:0008430)
0.1 4.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 3.8 GO:0005516 calmodulin binding(GO:0005516)
0.9 3.7 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 3.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 3.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 3.6 GO:0008017 microtubule binding(GO:0008017)
0.0 3.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 2.9 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 2.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 2.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 2.3 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0 2.3 GO:0002039 p53 binding(GO:0002039)
0.4 2.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.7 2.1 GO:0050827 toxin receptor binding(GO:0050827)
0.1 1.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)