Motif ID: Foxb1
Z-value: 0.753
Transcription factors associated with Foxb1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxb1 | ENSMUSG00000059246.4 | Foxb1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxb1 | mm10_v2_chr9_-_69760924_69760940 | -0.06 | 7.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.4 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.7 | 2.6 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
| 0.6 | 1.9 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.5 | 5.1 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.3 | 0.9 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
| 0.3 | 1.7 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.2 | 0.8 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.2 | 0.6 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.2 | 0.6 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.2 | 2.1 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.1 | 0.4 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.1 | 1.0 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.1 | 0.3 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274) |
| 0.1 | 0.4 | GO:1903898 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
| 0.1 | 0.4 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.1 | 2.0 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 0.2 | GO:0097274 | urea homeostasis(GO:0097274) |
| 0.1 | 0.8 | GO:0010748 | negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.1 | 0.5 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.1 | 0.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 0.3 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.1 | 0.3 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
| 0.1 | 0.7 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.0 | 0.5 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.0 | 5.0 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.0 | 0.4 | GO:0098907 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
| 0.0 | 0.6 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.4 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.3 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.0 | 0.1 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.0 | 0.5 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.0 | 0.1 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.0 | 0.4 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.0 | 0.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.0 | 0.6 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.0 | 0.2 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 0.0 | 0.8 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 1.1 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
| 0.0 | 0.2 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.0 | 0.1 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.0 | 0.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.0 | 0.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.8 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.0 | 0.3 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 0.2 | GO:0007097 | nuclear migration(GO:0007097) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.1 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.1 | 2.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 1.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 0.6 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.1 | 2.4 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.0 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 0.8 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.2 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
| 0.0 | 3.2 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 2.4 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.3 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.0 | 0.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 4.1 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 4.8 | GO:0000790 | nuclear chromatin(GO:0000790) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 5.6 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.4 | 2.0 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.3 | 2.4 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.3 | 0.8 | GO:0004686 | elongation factor-2 kinase activity(GO:0004686) |
| 0.2 | 0.8 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.2 | 5.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 0.9 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 1.1 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.1 | 0.6 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 1.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 0.6 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.7 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.1 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.0 | 0.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.0 | 1.9 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.3 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.0 | 0.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.5 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 0.1 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.0 | 1.0 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.4 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 0.2 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.7 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.3 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 3.5 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
| 0.0 | 1.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.6 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
