Motif ID: Foxc1

Z-value: 0.746


Transcription factors associated with Foxc1:

Gene SymbolEntrez IDGene Name
Foxc1 ENSMUSG00000050295.2 Foxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxc1mm10_v2_chr13_+_31806627_318066500.213.1e-01Click!


Activity profile for motif Foxc1.

activity profile for motif Foxc1


Sorted Z-values histogram for motif Foxc1

Sorted Z-values for motif Foxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxc1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_53525703 2.314 ENSMUST00000081132.4
Gm5449
predicted pseudogene 5449
chr19_+_60144682 1.245 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chrY_+_1010543 1.204 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr17_+_80944611 1.167 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr1_-_71653162 1.049 ENSMUST00000055226.6
Fn1
fibronectin 1
chr1_+_107511489 1.010 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr11_+_73160403 0.986 ENSMUST00000006104.3
P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_+_107511416 0.959 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr17_-_70851710 0.943 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr7_-_75308373 0.886 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b
chr1_+_45311538 0.842 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr15_-_66948419 0.784 ENSMUST00000167817.1
Ndrg1
N-myc downstream regulated gene 1
chr1_+_72824482 0.773 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr3_+_94377432 0.761 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr1_+_84839833 0.725 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr3_+_94377505 0.709 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr13_+_23934434 0.679 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr17_+_3397189 0.672 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr6_+_47244359 0.648 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr11_+_32300069 0.627 ENSMUST00000020535.1
Hbq1a
hemoglobin, theta 1A
chr2_+_50066429 0.606 ENSMUST00000112712.3
ENSMUST00000128451.1
ENSMUST00000053208.7
Lypd6


LY6/PLAUR domain containing 6


chr12_-_73047179 0.581 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr16_-_21947536 0.554 ENSMUST00000023562.7
Tmem41a
transmembrane protein 41a
chr2_+_4976113 0.535 ENSMUST00000167607.1
ENSMUST00000115010.2
Ucma

upper zone of growth plate and cartilage matrix associated

chr3_+_154597352 0.525 ENSMUST00000140644.1
ENSMUST00000144764.1
ENSMUST00000155232.1
Cryz


crystallin, zeta


chr11_-_78550777 0.523 ENSMUST00000103242.4
Tmem97
transmembrane protein 97
chr18_+_78349754 0.522 ENSMUST00000164064.1
Gm6133
predicted gene 6133
chr13_+_37826225 0.497 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr10_+_77864623 0.480 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr4_-_43030440 0.477 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chr3_+_154597197 0.469 ENSMUST00000155385.1
ENSMUST00000029850.8
Cryz

crystallin, zeta

chr12_-_69198419 0.466 ENSMUST00000021356.5
Dnaaf2
dynein, axonemal assembly factor 2
chr7_-_142656018 0.434 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr11_-_98625661 0.433 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr15_+_78597047 0.424 ENSMUST00000043069.5
Cyth4
cytohesin 4
chr2_-_172370506 0.417 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr12_-_113422730 0.411 ENSMUST00000177715.1
ENSMUST00000103426.1
Ighm

immunoglobulin heavy constant mu

chr16_-_46155077 0.409 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr9_-_103222063 0.394 ENSMUST00000170904.1
Trf
transferrin
chr1_-_5019342 0.388 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr13_-_54766553 0.379 ENSMUST00000036825.7
Sncb
synuclein, beta
chr17_+_45686322 0.375 ENSMUST00000024734.7
Mrpl14
mitochondrial ribosomal protein L14
chr15_-_102257306 0.361 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chr2_-_79908389 0.359 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr15_-_102257449 0.356 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr19_+_7268296 0.349 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr7_-_127026479 0.346 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_-_149636164 0.345 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr3_-_89998656 0.344 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr13_-_29984219 0.342 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr8_+_106870827 0.330 ENSMUST00000176144.1
ENSMUST00000175987.1
Has3

hyaluronan synthase 3

chr8_-_13494479 0.330 ENSMUST00000033828.5
Gas6
growth arrest specific 6
chr2_-_79908428 0.328 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr15_-_102667749 0.323 ENSMUST00000075630.3
Atp5g2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr11_+_68968107 0.312 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chr6_+_86371489 0.303 ENSMUST00000089558.5
Snrpg
small nuclear ribonucleoprotein polypeptide G
chr3_-_141982224 0.297 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr3_+_145987835 0.293 ENSMUST00000039517.6
Syde2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr1_+_75236439 0.293 ENSMUST00000082158.6
ENSMUST00000055223.7
Dnajb2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr9_-_51278540 0.284 ENSMUST00000114427.3
Gm684
predicted gene 684
chr6_-_42324640 0.277 ENSMUST00000031891.8
ENSMUST00000143278.1
Fam131b

family with sequence similarity 131, member B

chr6_-_42324554 0.271 ENSMUST00000095974.3
Fam131b
family with sequence similarity 131, member B
chr6_+_55203381 0.270 ENSMUST00000053094.7
Fam188b
family with sequence similarity 188, member B
chr11_+_69935796 0.268 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr6_+_68161415 0.266 ENSMUST00000168090.1
Igkv1-115
immunoglobulin kappa variable 1-115
chr3_-_87263703 0.265 ENSMUST00000146512.1
Fcrls
Fc receptor-like S, scavenger receptor
chr3_+_37312514 0.264 ENSMUST00000057975.7
ENSMUST00000108121.3
Bbs12

Bardet-Biedl syndrome 12 (human)

chr2_-_12301914 0.263 ENSMUST00000028106.4
Itga8
integrin alpha 8
chr15_+_82016369 0.263 ENSMUST00000069530.6
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr15_+_80255184 0.257 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr9_-_106891401 0.251 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr15_+_82016420 0.248 ENSMUST00000168581.1
ENSMUST00000170630.1
ENSMUST00000164779.1
Xrcc6


X-ray repair complementing defective repair in Chinese hamster cells 6


chr7_+_44816088 0.244 ENSMUST00000057195.9
ENSMUST00000107891.1
Nup62

nucleoporin 62

chr6_-_55175019 0.236 ENSMUST00000003569.5
Inmt
indolethylamine N-methyltransferase
chr10_-_14718191 0.234 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr15_-_76656905 0.233 ENSMUST00000176274.1
Cyhr1
cysteine and histidine rich 1
chr2_+_172370658 0.230 ENSMUST00000151511.1
ENSMUST00000116375.1
Cstf1

cleavage stimulation factor, 3' pre-RNA, subunit 1

chr1_-_131097535 0.225 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr3_+_61364507 0.222 ENSMUST00000049064.2
Rap2b
RAP2B, member of RAS oncogene family
chr17_-_36951636 0.219 ENSMUST00000040402.7
ENSMUST00000174711.1
Ppp1r11

protein phosphatase 1, regulatory (inhibitor) subunit 11

chr9_+_72806874 0.218 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chrY_+_90843934 0.207 ENSMUST00000178550.1
Gm21742
predicted gene, 21742
chr2_+_30807826 0.203 ENSMUST00000041830.3
ENSMUST00000152374.1
Ntmt1

N-terminal Xaa-Pro-Lys N-methyltransferase 1

chr1_-_82291370 0.201 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr4_-_40948196 0.199 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr17_-_36951338 0.194 ENSMUST00000173540.1
Ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chrX_-_102251852 0.193 ENSMUST00000101336.3
ENSMUST00000136277.1
Cited1

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

chr15_-_58034289 0.192 ENSMUST00000100655.3
9130401M01Rik
RIKEN cDNA 9130401M01 gene
chr1_+_34439851 0.189 ENSMUST00000027303.7
Imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr2_-_181365306 0.182 ENSMUST00000108808.1
ENSMUST00000170190.1
ENSMUST00000127988.1
Arfrp1


ADP-ribosylation factor related protein 1


chr9_-_83146601 0.182 ENSMUST00000162246.2
ENSMUST00000161796.2
Hmgn3

high mobility group nucleosomal binding domain 3

chr14_+_52016849 0.176 ENSMUST00000100638.2
Tmem253
transmembrane protein 253
chr2_-_156839790 0.175 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr2_-_126709567 0.174 ENSMUST00000099423.2
Gm10774
predicted pseudogene 10774
chr5_+_119834663 0.170 ENSMUST00000018407.6
Tbx5
T-box 5
chr6_+_92940572 0.170 ENSMUST00000181145.1
ENSMUST00000181840.1
9530026P05Rik

RIKEN cDNA 9530026P05 gene

chr11_+_6415443 0.164 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr2_+_151542483 0.163 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr14_+_67716095 0.162 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr5_+_8046077 0.162 ENSMUST00000088786.4
Sri
sorcin
chr18_+_58556224 0.161 ENSMUST00000025500.6
Slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr1_+_74284930 0.161 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr13_+_83732438 0.160 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr3_-_57294880 0.150 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr17_-_57011271 0.147 ENSMUST00000002733.6
Gtf2f1
general transcription factor IIF, polypeptide 1
chr3_+_90079540 0.145 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
Tpm3


tropomyosin 3, gamma


chr16_+_20674111 0.145 ENSMUST00000151679.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr7_+_19228334 0.138 ENSMUST00000063976.8
Opa3
optic atrophy 3
chr14_+_113314602 0.137 ENSMUST00000072359.6
Tpm3-rs7
tropomyosin 3, related sequence 7
chr7_+_119760918 0.136 ENSMUST00000106527.1
ENSMUST00000106528.1
ENSMUST00000063770.3
ENSMUST00000106529.1
Acsm3



acyl-CoA synthetase medium-chain family member 3



chr9_+_38718263 0.132 ENSMUST00000001544.5
ENSMUST00000118144.1
Vwa5a

von Willebrand factor A domain containing 5A

chr4_+_117550326 0.130 ENSMUST00000037127.8
Eri3
exoribonuclease 3
chr5_-_77115145 0.130 ENSMUST00000081964.5
Hopx
HOP homeobox
chr12_+_76370266 0.130 ENSMUST00000042779.3
Zbtb1
zinc finger and BTB domain containing 1
chr14_+_31641051 0.128 ENSMUST00000090147.6
Btd
biotinidase
chr1_-_74284636 0.123 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr11_+_3202612 0.120 ENSMUST00000110049.1
Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_+_95124476 0.118 ENSMUST00000131597.1
ENSMUST00000005769.6
ENSMUST00000107227.1
Tmod4


tropomodulin 4


chr7_-_44892358 0.116 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr9_-_67049143 0.114 ENSMUST00000113687.1
ENSMUST00000113693.1
ENSMUST00000113701.1
ENSMUST00000034928.5
ENSMUST00000113685.3
ENSMUST00000030185.4
ENSMUST00000050905.9
ENSMUST00000113705.1
ENSMUST00000113697.1
ENSMUST00000113707.2
Tpm1









tropomyosin 1, alpha









chr7_-_51862216 0.112 ENSMUST00000169357.1
Fancf
Fanconi anemia, complementation group F
chr12_+_4234023 0.104 ENSMUST00000179139.1
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr4_+_98923810 0.104 ENSMUST00000030289.2
Usp1
ubiquitin specific peptidase 1
chr6_-_29212240 0.096 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr4_+_98923845 0.093 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr3_-_87263518 0.091 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr1_+_163994866 0.091 ENSMUST00000111490.1
ENSMUST00000045694.7
Mettl18

methyltransferase like 18

chrX_-_101222426 0.083 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr8_-_25840440 0.080 ENSMUST00000110609.1
Ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr9_-_71592265 0.076 ENSMUST00000169573.1
ENSMUST00000166843.1
ENSMUST00000163998.1
Myzap
Gcom1

myocardial zonula adherens protein
GRINL1A complex locus

chr16_-_59632520 0.076 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr12_-_87443800 0.071 ENSMUST00000162961.1
Alkbh1
alkB, alkylation repair homolog 1 (E. coli)
chr11_-_96829483 0.069 ENSMUST00000167149.1
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr6_+_17281185 0.062 ENSMUST00000000058.6
Cav2
caveolin 2
chr16_+_35983424 0.062 ENSMUST00000173555.1
Kpna1
karyopherin (importin) alpha 1
chr7_-_89941084 0.060 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6

lethal, Chr 7, Rinchik 6

chr8_-_41417042 0.059 ENSMUST00000033999.6
Frg1
FSHD region gene 1
chr2_+_35622010 0.054 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr15_-_78405824 0.051 ENSMUST00000058659.7
Tst
thiosulfate sulfurtransferase, mitochondrial
chr4_-_42084291 0.051 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chrX_-_102252154 0.048 ENSMUST00000050551.3
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr1_-_87394721 0.048 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr11_-_102296618 0.046 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr9_+_110419750 0.045 ENSMUST00000035061.6
Ngp
neutrophilic granule protein
chrX_+_101449078 0.044 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr9_-_50739365 0.044 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr13_-_29855630 0.039 ENSMUST00000091674.5
ENSMUST00000006353.7
Cdkal1

CDK5 regulatory subunit associated protein 1-like 1

chr3_-_96197580 0.038 ENSMUST00000016087.3
Bola1
bolA-like 1 (E. coli)
chr15_+_6422240 0.037 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr5_-_100038869 0.035 ENSMUST00000153442.1
Hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
chr3_+_94837533 0.032 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr18_-_33463615 0.031 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr17_+_37045980 0.031 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr5_+_98854434 0.030 ENSMUST00000031278.4
Bmp3
bone morphogenetic protein 3
chr2_+_163994960 0.029 ENSMUST00000018470.3
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr4_-_59783800 0.027 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr13_-_107414742 0.027 ENSMUST00000061241.6
Apoo-ps
apolipoprotein O, pseudogene
chr2_+_127208358 0.025 ENSMUST00000103220.3
Snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr17_+_16972910 0.022 ENSMUST00000071374.5
BC002059
cDNA sequence BC002059
chr2_+_62664279 0.017 ENSMUST00000028257.2
Gca
grancalcin
chr15_-_82244716 0.015 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr2_-_103485068 0.013 ENSMUST00000111168.3
Cat
catalase
chr13_+_65512678 0.011 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr11_+_101082565 0.008 ENSMUST00000001806.3
ENSMUST00000107308.3
Coasy

Coenzyme A synthase

chr17_-_45686120 0.001 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161)
0.2 1.5 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.2 0.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.2 0.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.1 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2 0.5 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.1 0.6 GO:0071205 clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205)
0.1 0.5 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.3 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.3 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) hematopoietic stem cell migration(GO:0035701) regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.4 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.1 0.3 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 1.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.3 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.8 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 1.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 1.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1 0.2 GO:0071105 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 0.2 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.1 0.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.4 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 0.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.3 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.4 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.5 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 2.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0036324 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.4 GO:0018208 peptidyl-proline modification(GO:0018208)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.1 0.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 1.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.2 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 1.0 GO:0045340 mercury ion binding(GO:0045340)
0.2 0.5 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0070402 NADPH binding(GO:0070402)
0.1 1.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)