Motif ID: Foxd1

Z-value: 1.171


Transcription factors associated with Foxd1:

Gene SymbolEntrez IDGene Name
Foxd1 ENSMUSG00000078302.3 Foxd1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxd1mm10_v2_chr13_+_98354234_98354250-0.203.3e-01Click!


Activity profile for motif Foxd1.

activity profile for motif Foxd1


Sorted Z-values histogram for motif Foxd1

Sorted Z-values for motif Foxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 8.134 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr8_-_84773381 7.103 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr4_+_144893077 6.260 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_144893127 5.505 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr13_-_51701041 4.878 ENSMUST00000110042.1
 Gm15440
predicted gene 15440
chr8_-_84978709 4.495 ENSMUST00000064922.5
 Junb
Jun-B oncogene
chr13_-_93499803 4.384 ENSMUST00000065537.7
 Jmy
junction-mediating and regulatory protein
chr18_-_43059418 4.304 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr16_-_4880284 4.268 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr12_-_100725028 4.235 ENSMUST00000043599.6
 Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr6_+_135362931 4.190 ENSMUST00000032330.9
 Emp1
epithelial membrane protein 1
chr18_+_69344503 4.151 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr10_-_8518801 4.128 ENSMUST00000061601.7
 Ust
uronyl-2-sulfotransferase
chr16_-_74411292 4.107 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr11_+_3332426 4.056 ENSMUST00000136474.1
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr10_+_29211637 3.588 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr7_+_110772604 3.371 ENSMUST00000005829.6
 Ampd3
adenosine monophosphate deaminase 3
chr16_-_22439719 3.294 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr3_+_96557950 3.283 ENSMUST00000074519.6
ENSMUST00000049093.7
 Txnip

thioredoxin interacting protein

chr15_+_3270767 3.220 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 19.9 GO:0042572 retinol metabolic process(GO:0042572)
1.4 9.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 7.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.5 7.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.3 6.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.2 4.8 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 4.8 GO:0030010 establishment of cell polarity(GO:0030010)
1.6 4.7 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.4 4.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.1 4.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.6 4.3 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
1.4 4.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.4 4.2 GO:0042118 endothelial cell activation(GO:0042118)
0.2 4.2 GO:0032060 bleb assembly(GO:0032060)
1.4 4.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 4.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.4 3.4 GO:0032264 IMP salvage(GO:0032264)
0.4 3.3 GO:0002347 response to tumor cell(GO:0002347)
0.5 3.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 3.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 7.2 GO:0031252 cell leading edge(GO:0031252)
0.5 6.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 5.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 5.2 GO:0097060 synaptic membrane(GO:0097060)
0.3 4.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.9 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 4.7 GO:0035861 site of double-strand break(GO:0035861)
0.1 4.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 4.2 GO:0005769 early endosome(GO:0005769)
0.1 4.1 GO:0030673 axolemma(GO:0030673)
0.0 4.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 3.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 3.0 GO:0044307 dendritic branch(GO:0044307)
0.2 2.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 2.7 GO:0071564 npBAF complex(GO:0071564)
0.3 2.5 GO:0033391 chromatoid body(GO:0033391)
0.8 2.3 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 2.3 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 19.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
3.2 9.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 5.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 4.8 GO:0051117 ATPase binding(GO:0051117)
0.3 4.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
1.4 4.2 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
1.0 4.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 4.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.5 3.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 3.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 3.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.2 3.2 GO:0008430 selenium binding(GO:0008430)
0.2 3.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 3.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.6 2.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 2.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 2.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.7 2.6 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)