Motif ID: Foxd2

Z-value: 0.880


Transcription factors associated with Foxd2:

Gene SymbolEntrez IDGene Name
Foxd2 ENSMUSG00000055210.3 Foxd2



Activity profile for motif Foxd2.

activity profile for motif Foxd2


Sorted Z-values histogram for motif Foxd2

Sorted Z-values for motif Foxd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_37504264 5.429 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr5_-_104114088 5.158 ENSMUST00000031249.3
Sparcl1
SPARC-like 1
chr4_-_136898803 4.409 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr14_+_101840602 4.259 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr14_+_101840501 3.648 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr14_-_30353468 2.759 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr16_+_43508118 2.579 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr3_+_89520152 2.551 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr4_-_14621805 2.549 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr13_+_16014457 2.257 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr15_+_92597104 2.163 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr18_+_37513652 2.075 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr14_+_80000292 2.073 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr19_+_26748268 1.969 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr15_+_3270767 1.960 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr18_+_51117754 1.898 ENSMUST00000116639.2
Prr16
proline rich 16
chr2_-_45110336 1.892 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr7_-_61982348 1.886 ENSMUST00000181804.1
ENSMUST00000181187.1
A330076H08Rik

RIKEN cDNA A330076H08 gene

chr9_-_20879718 1.700 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr16_+_43235856 1.573 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr16_-_4880284 1.547 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr6_+_77242644 1.507 ENSMUST00000159616.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242715 1.441 ENSMUST00000161677.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr7_-_61982290 1.427 ENSMUST00000180481.1
A330076H08Rik
RIKEN cDNA A330076H08 gene
chr18_+_37725706 1.380 ENSMUST00000066149.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr2_-_62483637 1.302 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chrX_+_159697308 1.259 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_+_14388316 1.233 ENSMUST00000114731.1
ENSMUST00000082290.7
Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr16_+_13986596 1.208 ENSMUST00000056521.5
ENSMUST00000118412.1
ENSMUST00000131608.1
2900011O08Rik


RIKEN cDNA 2900011O08 gene


chr5_-_103100054 1.136 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr12_+_103434211 1.124 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr17_-_35046726 1.107 ENSMUST00000097338.4
Msh5
mutS homolog 5 (E. coli)
chr1_-_126830632 1.103 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr13_+_83732438 1.022 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr18_+_37674303 0.993 ENSMUST00000073447.5
Pcdhga9
protocadherin gamma subfamily A, 9
chr11_-_69369377 0.936 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr6_+_13069758 0.926 ENSMUST00000124234.1
ENSMUST00000142211.1
ENSMUST00000031556.7
Tmem106b


transmembrane protein 106B


chr9_-_95750335 0.921 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr1_-_132367879 0.913 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chrX_-_105929206 0.858 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr10_+_67096456 0.828 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chr2_+_120977017 0.790 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr5_+_107497718 0.764 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chrX_-_105929333 0.749 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr5_+_107497762 0.743 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr1_+_171840607 0.729 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr9_-_78109020 0.727 ENSMUST00000001402.7
Fbxo9
f-box protein 9
chrX_-_105929397 0.712 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr4_-_14621669 0.701 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr2_-_122702615 0.690 ENSMUST00000005952.4
ENSMUST00000099457.3
Slc30a4

solute carrier family 30 (zinc transporter), member 4

chr2_-_73312701 0.679 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr11_+_97801917 0.677 ENSMUST00000127033.2
Lasp1
LIM and SH3 protein 1
chr1_+_172698046 0.673 ENSMUST00000038495.3
Crp
C-reactive protein, pentraxin-related
chr5_-_31295862 0.646 ENSMUST00000041266.7
ENSMUST00000172435.1
Fndc4

fibronectin type III domain containing 4

chr6_-_54972603 0.628 ENSMUST00000060655.8
Nod1
nucleotide-binding oligomerization domain containing 1
chr14_-_70630149 0.620 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr10_-_128744014 0.587 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr2_-_86347764 0.570 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr17_-_78418083 0.555 ENSMUST00000070039.7
ENSMUST00000112487.1
Fez2

fasciculation and elongation protein zeta 2 (zygin II)

chr11_+_75650501 0.531 ENSMUST00000102505.3
Myo1c
myosin IC
chr12_-_110840905 0.484 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
Stk30


serine/threonine kinase 30


chr13_-_97747373 0.467 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_+_125136692 0.441 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr9_-_89092835 0.420 ENSMUST00000167113.1
Trim43b
tripartite motif-containing 43B
chr6_+_136518820 0.397 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr15_+_78935177 0.392 ENSMUST00000145157.1
ENSMUST00000123013.1
Nol12

nucleolar protein 12

chr1_-_170867761 0.372 ENSMUST00000027974.6
Atf6
activating transcription factor 6
chr19_-_29753600 0.330 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr1_-_126830786 0.282 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr12_+_38783503 0.231 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr2_+_14388434 0.222 ENSMUST00000133258.1
Slc39a12
solute carrier family 39 (zinc transporter), member 12
chr10_+_42860776 0.221 ENSMUST00000105494.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr6_+_38918969 0.210 ENSMUST00000003017.6
Tbxas1
thromboxane A synthase 1, platelet
chr1_-_37496095 0.198 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr13_+_5861489 0.192 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr18_+_73863672 0.184 ENSMUST00000134847.1
Mro
maestro
chr17_-_56276750 0.178 ENSMUST00000058136.8
Ticam1
toll-like receptor adaptor molecule 1
chr15_+_99393574 0.174 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr11_+_75999912 0.166 ENSMUST00000066408.5
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chr13_-_18031616 0.157 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr1_+_171411305 0.156 ENSMUST00000161241.1
ENSMUST00000159207.1
Usf1

upstream transcription factor 1

chr9_+_36832684 0.149 ENSMUST00000034630.8
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr6_+_61180313 0.141 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr19_+_57452900 0.126 ENSMUST00000026073.6
ENSMUST00000026072.3
Trub1

TruB pseudouridine (psi) synthase homolog 1 (E. coli)

chr7_-_127195875 0.125 ENSMUST00000035771.3
ENSMUST00000166791.1
Cd2bp2

CD2 antigen (cytoplasmic tail) binding protein 2

chr5_-_120612558 0.122 ENSMUST00000140554.1
ENSMUST00000031599.2
ENSMUST00000177800.1
1110008J03Rik


RIKEN cDNA 1110008J03 gene


chr9_+_94669876 0.101 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr1_-_157256682 0.095 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr1_-_57970104 0.084 ENSMUST00000114410.3
Kctd18
potassium channel tetramerisation domain containing 18
chr9_+_78109188 0.079 ENSMUST00000118869.1
ENSMUST00000125615.1
Ick

intestinal cell kinase

chr4_+_150087365 0.060 ENSMUST00000094451.3
Gpr157
G protein-coupled receptor 157
chr15_+_99393610 0.044 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr8_-_123754138 0.041 ENSMUST00000181805.1
4732419C18Rik
RIKEN cDNA 4732419C18 gene
chr2_+_152669461 0.029 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
H13



histocompatibility 13



chr1_-_57970032 0.020 ENSMUST00000159826.1
Kctd18
potassium channel tetramerisation domain containing 18
chr10_-_11080956 0.018 ENSMUST00000105560.1
Grm1
glutamate receptor, metabotropic 1
chr7_-_87493371 0.007 ENSMUST00000004770.5
Tyr
tyrosinase
chr18_-_6516089 0.006 ENSMUST00000115870.2
Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr13_+_119606650 0.001 ENSMUST00000178948.1
Gm21967
predicted gene, 21967

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.6 2.3 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.5 3.2 GO:0019532 oxalate transport(GO:0019532)
0.5 2.3 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.3 1.9 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 2.0 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 1.1 GO:0051026 chiasma assembly(GO:0051026)
0.3 5.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.7 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.2 2.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.6 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.2 0.6 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.2 1.2 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.2 1.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 1.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 4.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 2.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.9 GO:0046541 saliva secretion(GO:0046541)
0.1 0.7 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:0016598 protein arginylation(GO:0016598)
0.1 2.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 1.1 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.9 GO:0032418 lysosome localization(GO:0032418)
0.0 0.6 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0043512 inhibin A complex(GO:0043512)
0.6 2.3 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 2.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.5 GO:0045160 myosin I complex(GO:0045160)
0.2 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 2.1 GO:0042581 specific granule(GO:0042581)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 7.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.4 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)
0.0 5.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.6 GO:0030426 growth cone(GO:0030426)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.5 2.8 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.4 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 2.3 GO:0015616 DNA translocase activity(GO:0015616)
0.3 3.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 7.9 GO:0042805 actinin binding(GO:0042805)
0.2 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.0 GO:0008430 selenium binding(GO:0008430)
0.1 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 2.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.1 GO:0005521 lamin binding(GO:0005521)
0.1 1.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 4.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)