Motif ID: Foxf2

Z-value: 1.062


Transcription factors associated with Foxf2:

Gene SymbolEntrez IDGene Name
Foxf2 ENSMUSG00000038402.2 Foxf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf2mm10_v2_chr13_+_31625802_316258160.626.5e-04Click!


Activity profile for motif Foxf2.

activity profile for motif Foxf2


Sorted Z-values histogram for motif Foxf2

Sorted Z-values for motif Foxf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 105 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66969616 12.880 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr8_-_84773381 8.707 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr6_-_148444336 6.061 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr10_+_60106452 3.921 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr4_+_101507947 3.738 ENSMUST00000149047.1
ENSMUST00000106929.3
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr7_+_82175156 3.528 ENSMUST00000180243.1
 Sh3gl3
SH3-domain GRB2-like 3
chr4_+_101507855 3.249 ENSMUST00000038207.5
 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_-_144202300 3.144 ENSMUST00000121796.1
ENSMUST00000121112.1
 Lmo4

LIM domain only 4

chr16_-_4880284 3.128 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr14_-_51913393 3.118 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chr17_+_70522083 3.048 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr7_+_44849581 3.040 ENSMUST00000150335.1
ENSMUST00000107882.1
 Akt1s1

AKT1 substrate 1 (proline-rich)

chr12_-_112511136 2.912 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr7_+_45783883 2.811 ENSMUST00000072580.5
 Lmtk3
lemur tyrosine kinase 3
chr7_+_45783686 2.730 ENSMUST00000118564.1
ENSMUST00000133428.1
 Lmtk3

lemur tyrosine kinase 3

chr7_-_4844665 2.666 ENSMUST00000066041.5
ENSMUST00000172377.1
 Shisa7

shisa homolog 7 (Xenopus laevis)

chr16_+_91269759 2.480 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr5_+_90903864 2.350 ENSMUST00000075433.6
 Cxcl2
chemokine (C-X-C motif) ligand 2
chr17_+_70522149 2.330 ENSMUST00000140728.1
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr4_+_5724304 2.269 ENSMUST00000108380.1
 Fam110b
family with sequence similarity 110, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 12.9 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.6 8.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 7.9 GO:0045792 negative regulation of cell size(GO:0045792)
1.2 7.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 5.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.4 5.4 GO:0070842 aggresome assembly(GO:0070842)
0.4 3.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6 3.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 3.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 3.1 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.2 2.3 GO:0007379 segment specification(GO:0007379)
0.1 2.3 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023)
0.3 2.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 2.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.4 2.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 2.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 2.0 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.6 1.9 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 1.9 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.6 1.8 GO:0002159 desmosome assembly(GO:0002159)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 16.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 13.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.6 7.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 3.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.5 GO:0005769 early endosome(GO:0005769)
0.1 2.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.0 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 1.9 GO:0005802 trans-Golgi network(GO:0005802)
0.2 1.8 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.3 GO:0071437 invadopodium(GO:0071437)
0.0 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.3 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 0.8 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 12.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 7.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 7.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 3.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.7 3.7 GO:0097001 ceramide binding(GO:0097001)
0.3 2.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.2 GO:0008430 selenium binding(GO:0008430)
0.0 2.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.2 GO:0008565 protein transporter activity(GO:0008565)
0.7 2.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 2.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 2.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.4 1.9 GO:0071253 connexin binding(GO:0071253)
0.2 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 1.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.4 1.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.0 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)