Motif ID: Foxl1

Z-value: 0.301


Transcription factors associated with Foxl1:

Gene SymbolEntrez IDGene Name
Foxl1 ENSMUSG00000097084.1 Foxl1
Foxl1 ENSMUSG00000043867.5 Foxl1



Activity profile for motif Foxl1.

activity profile for motif Foxl1


Sorted Z-values histogram for motif Foxl1

Sorted Z-values for motif Foxl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_102490418 0.924 ENSMUST00000020040.3
Nts
neurotensin
chr16_+_45093611 0.875 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr16_-_22439570 0.675 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr1_-_170110491 0.501 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr7_+_122289297 0.380 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr16_+_30065333 0.369 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr16_+_43508118 0.354 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr4_+_11191726 0.258 ENSMUST00000029866.9
ENSMUST00000108324.3
Ccne2

cyclin E2

chrX_-_94123087 0.214 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr2_+_91256144 0.203 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr2_+_91255954 0.194 ENSMUST00000134699.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr17_-_91092715 0.169 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
Nrxn1


neurexin I


chr7_+_91090728 0.158 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr7_+_91090697 0.156 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr12_+_69963452 0.152 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr2_+_119325784 0.125 ENSMUST00000102517.3
Dll4
delta-like 4 (Drosophila)
chrX_+_112604274 0.119 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr10_+_56377300 0.119 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr2_-_94264745 0.118 ENSMUST00000134563.1
E530001K10Rik
RIKEN cDNA E530001K10 gene
chr18_+_34409415 0.100 ENSMUST00000166156.1
ENSMUST00000014647.7
Pkd2l2

polycystic kidney disease 2-like 2

chr13_+_23555023 0.100 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr13_-_23622502 0.098 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr11_+_31872100 0.094 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr13_+_23575753 0.085 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chrX_+_18162575 0.082 ENSMUST00000044484.6
ENSMUST00000052368.8
Kdm6a

lysine (K)-specific demethylase 6A

chr13_+_23738804 0.074 ENSMUST00000040914.1
Hist1h1c
histone cluster 1, H1c
chr15_+_43477213 0.057 ENSMUST00000022962.6
Emc2
ER membrane protein complex subunit 2
chr9_-_101198999 0.057 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr9_+_44069421 0.056 ENSMUST00000114830.2
Usp2
ubiquitin specific peptidase 2
chr2_-_59948155 0.051 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr10_+_88091070 0.040 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr13_+_23763660 0.023 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chrM_+_2743 0.017 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0021557 oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0072554 blood vessel lumenization(GO:0072554)
0.0 0.1 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0060746 parental behavior(GO:0060746)
0.0 0.9 GO:0008542 visual learning(GO:0008542)
0.0 0.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)