Motif ID: Foxm1

Z-value: 0.645


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_128363058-0.067.7e-01Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 161 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_138842429 1.774 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr12_-_56536895 1.668 ENSMUST00000001536.8
 Nkx2-1
NK2 homeobox 1
chrX_-_141725181 1.493 ENSMUST00000067841.7
 Irs4
insulin receptor substrate 4
chr15_+_98167806 1.380 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr4_-_44710408 1.331 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
 Pax5









paired box gene 5









chr2_+_104095796 1.073 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr18_-_65939048 1.027 ENSMUST00000025396.3
 Rax
retina and anterior neural fold homeobox
chr1_-_79440039 1.000 ENSMUST00000049972.4
 Scg2
secretogranin II
chr2_+_65845833 0.911 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr19_-_58455161 0.785 ENSMUST00000135730.1
ENSMUST00000152507.1
 Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr2_+_65845767 0.754 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr19_-_58455398 0.748 ENSMUST00000026076.7
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr11_-_100354040 0.723 ENSMUST00000173630.1
 Hap1
huntingtin-associated protein 1
chr5_-_103211251 0.691 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
 Mapk10



mitogen-activated protein kinase 10



chr1_+_74713551 0.611 ENSMUST00000027356.5
 Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr19_-_58455903 0.609 ENSMUST00000131877.1
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr16_-_23890805 0.581 ENSMUST00000004480.3
 Sst
somatostatin
chr10_-_130280218 0.569 ENSMUST00000061571.3
 Neurod4
neurogenic differentiation 4
chr3_+_106113229 0.556 ENSMUST00000079132.5
ENSMUST00000139086.1
 Chia

chitinase, acidic

chr11_-_42000284 0.537 ENSMUST00000109292.2
ENSMUST00000109290.1
 Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.6 1.7 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.3 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.1 1.1 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.0 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 1.0 GO:0021854 hypothalamus development(GO:0021854)
0.2 0.7 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.3 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.3 GO:0046898 response to cycloheximide(GO:0046898)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.1 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 1.5 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 1.1 GO:0001848 complement binding(GO:0001848)
0.1 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.2 GO:0050827 toxin receptor binding(GO:0050827)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)