Motif ID: Foxo4

Z-value: 0.974


Transcription factors associated with Foxo4:

Gene SymbolEntrez IDGene Name
Foxo4 ENSMUSG00000042903.7 Foxo4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo4mm10_v2_chrX_+_101254528_1012545740.432.8e-02Click!


Activity profile for motif Foxo4.

activity profile for motif Foxo4


Sorted Z-values histogram for motif Foxo4

Sorted Z-values for motif Foxo4



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxo4

PNG image of the network

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Top targets:


Showing 1 to 20 of 91 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_50030735 3.427 ENSMUST00000071866.1
 Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr13_-_8940977 3.362 ENSMUST00000071184.2
 Rpl10a-ps2
ribosomal protein L10A, pseudogene 2
chr4_-_97778042 2.053 ENSMUST00000146447.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr14_-_98169542 1.845 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr4_+_8690399 1.825 ENSMUST00000127476.1
 Chd7
chromodomain helicase DNA binding protein 7
chr1_+_6487231 1.555 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr7_-_4778141 1.545 ENSMUST00000094892.5
 Il11
interleukin 11
chr2_-_175931051 1.543 ENSMUST00000108949.2
ENSMUST00000109018.2
 Gm8898

predicted gene 8898

chr7_-_89517576 1.527 ENSMUST00000041761.5
 Prss23
protease, serine, 23
chr6_+_95117740 1.431 ENSMUST00000032107.7
ENSMUST00000119582.1
 Kbtbd8

kelch repeat and BTB (POZ) domain containing 8

chr2_+_176521056 1.403 ENSMUST00000108997.2
ENSMUST00000178443.1
 Gm14431

predicted gene 14431

chr2_+_181767283 1.396 ENSMUST00000108757.2
 Myt1
myelin transcription factor 1
chr8_+_79639618 1.374 ENSMUST00000173078.1
ENSMUST00000173286.1
 Otud4

OTU domain containing 4

chr2_-_175141999 1.304 ENSMUST00000109062.1
ENSMUST00000109059.1
ENSMUST00000109060.1
 Gm14399


predicted gene 14399


chr2_+_175372436 1.235 ENSMUST00000131676.1
ENSMUST00000109048.2
ENSMUST00000109047.2
 Gm4723


predicted gene 4723


chr2_+_175469985 1.217 ENSMUST00000109042.3
ENSMUST00000109002.2
ENSMUST00000109043.2
ENSMUST00000143490.1
 Gm8923



predicted gene 8923



chr2_+_181767040 1.202 ENSMUST00000108756.1
 Myt1
myelin transcription factor 1
chr7_-_25250720 1.182 ENSMUST00000116343.2
ENSMUST00000045847.8
 Erf

Ets2 repressor factor

chr2_-_175703646 1.173 ENSMUST00000109027.2
ENSMUST00000179061.1
ENSMUST00000131041.1
 Gm4245


predicted gene 4245


chrX_+_134601179 1.113 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
 Hnrnph2


heterogeneous nuclear ribonucleoprotein H2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.6 GO:0060539 diaphragm development(GO:0060539)
0.6 1.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.6 1.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 1.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.5 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.0 1.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 1.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 1.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.3 0.9 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.8 GO:1904749 rRNA export from nucleus(GO:0006407) regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.7 GO:0045349 regulation of dendritic cell cytokine production(GO:0002730) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.7 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.0 0.6 GO:0060074 synapse maturation(GO:0060074)
0.2 0.5 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 0.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701) response to arsenic-containing substance(GO:0046685)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.8 GO:0001652 granular component(GO:0001652)
0.0 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.6 1.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.2 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.5 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)