Motif ID: Foxo6

Z-value: 0.622


Transcription factors associated with Foxo6:

Gene SymbolEntrez IDGene Name
Foxo6 ENSMUSG00000052135.8 Foxo6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo6mm10_v2_chr4_-_120287349_120287349-0.877.8e-09Click!


Activity profile for motif Foxo6.

activity profile for motif Foxo6


Sorted Z-values histogram for motif Foxo6

Sorted Z-values for motif Foxo6



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxo6

PNG image of the network

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Top targets:


Showing 1 to 20 of 79 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 3.234 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr11_-_12027958 1.842 ENSMUST00000109654.1
 Grb10
growth factor receptor bound protein 10
chr4_+_134510999 1.826 ENSMUST00000105866.2
 Aunip
aurora kinase A and ninein interacting protein
chr1_+_51987139 1.779 ENSMUST00000168302.1
 Stat4
signal transducer and activator of transcription 4
chr5_+_110330697 1.663 ENSMUST00000112481.1
 Pole
polymerase (DNA directed), epsilon
chr5_-_99037035 1.611 ENSMUST00000031277.6
 Prkg2
protein kinase, cGMP-dependent, type II
chr19_-_45742873 1.587 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8


chr2_-_67194695 1.496 ENSMUST00000147939.1
 Gm13598
predicted gene 13598
chrX_+_106920618 1.321 ENSMUST00000060576.7
 Lpar4
lysophosphatidic acid receptor 4
chr17_-_31277327 1.289 ENSMUST00000024832.7
 Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr11_+_46235460 1.223 ENSMUST00000060185.2
 Fndc9
fibronectin type III domain containing 9
chr14_-_47418407 1.183 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr12_-_91384403 1.173 ENSMUST00000141429.1
 Cep128
centrosomal protein 128
chr11_-_89639631 1.045 ENSMUST00000128717.1
 Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr9_+_6168638 0.822 ENSMUST00000058692.7
 Pdgfd
platelet-derived growth factor, D polypeptide
chr7_-_123369870 0.780 ENSMUST00000106442.2
ENSMUST00000098060.3
ENSMUST00000167309.1
 Arhgap17


Rho GTPase activating protein 17


chr1_-_184883218 0.771 ENSMUST00000048308.5
 C130074G19Rik
RIKEN cDNA C130074G19 gene
chr15_+_3270767 0.749 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chrY_-_6681243 0.733 ENSMUST00000115940.1
 Gm21719
predicted gene, 21719
chr5_-_117389029 0.725 ENSMUST00000111953.1
ENSMUST00000086461.6
 Rfc5

replication factor C (activator 1) 5


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 2.9 GO:0007051 spindle organization(GO:0007051)
0.2 1.8 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 1.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.5 1.6 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 1.6 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 1.3 GO:0035082 axoneme assembly(GO:0035082)
0.1 1.0 GO:0050957 equilibrioception(GO:0050957)
0.0 1.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 0.8 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.6 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1 0.6 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.5 GO:1903887 motile primary cilium assembly(GO:1903887)
0.1 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0000922 spindle pole(GO:0000922)
0.3 1.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.3 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 1.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.4 1.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 1.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.7 GO:0008430 selenium binding(GO:0008430)
0.2 0.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.6 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 0.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.5 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.4 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)