Motif ID: Foxp1_Foxj2

Z-value: 1.482

Transcription factors associated with Foxp1_Foxj2:

Gene SymbolEntrez IDGene Name
Foxj2 ENSMUSG00000003154.9 Foxj2
Foxp1 ENSMUSG00000030067.11 Foxp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj2mm10_v2_chr6_+_122819888_1228199380.952.2e-13Click!
Foxp1mm10_v2_chr6_-_99521153_995211670.331.0e-01Click!


Activity profile for motif Foxp1_Foxj2.

activity profile for motif Foxp1_Foxj2


Sorted Z-values histogram for motif Foxp1_Foxj2

Sorted Z-values for motif Foxp1_Foxj2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp1_Foxj2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 17.592 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr15_-_66969616 7.719 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr14_-_51913393 7.657 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chr9_-_121495678 7.368 ENSMUST00000035120.4
 Cck
cholecystokinin
chr17_+_35076902 6.647 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr6_-_148444336 6.437 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr8_+_66386292 6.342 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr4_-_151108244 5.875 ENSMUST00000131948.1
 Camta1
calmodulin binding transcription activator 1
chr2_+_136713444 5.749 ENSMUST00000028727.4
ENSMUST00000110098.3
 Snap25

synaptosomal-associated protein 25

chr19_-_34255325 5.656 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chr7_+_16310412 5.349 ENSMUST00000136781.1
 Bbc3
BCL2 binding component 3
chr15_-_58214882 5.280 ENSMUST00000022986.6
 Fbxo32
F-box protein 32
chr16_-_4880284 5.186 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr17_+_70522083 5.143 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr17_+_70561739 4.920 ENSMUST00000097288.2
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chrX_+_163911401 4.912 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr9_-_40455670 4.755 ENSMUST00000165104.1
ENSMUST00000045682.5
 Gramd1b

GRAM domain containing 1B

chr5_+_122643878 4.649 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
 P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr7_+_110772604 4.612 ENSMUST00000005829.6
 Ampd3
adenosine monophosphate deaminase 3
chr4_-_87806296 4.561 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 363 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 16.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.1 13.8 GO:0070842 aggresome assembly(GO:0070842)
0.5 13.6 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.7 10.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.9 9.9 GO:0042572 retinol metabolic process(GO:0042572)
0.8 9.2 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.3 9.1 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 8.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 8.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 7.8 GO:0016082 synaptic vesicle priming(GO:0016082)
1.9 7.7 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3 7.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 7.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 7.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 7.2 GO:0042118 endothelial cell activation(GO:0042118)
0.7 7.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.7 7.0 GO:0007379 segment specification(GO:0007379)
1.2 6.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 6.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.7 6.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 151 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 26.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 23.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 14.8 GO:0030018 Z disc(GO:0030018)
0.3 10.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.9 10.3 GO:0031931 TORC1 complex(GO:0031931)
0.1 8.9 GO:0097060 synaptic membrane(GO:0097060)
0.3 8.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 8.1 GO:0045202 synapse(GO:0045202)
0.1 7.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.5 7.4 GO:0043203 axon hillock(GO:0043203)
0.1 7.3 GO:0005802 trans-Golgi network(GO:0005802)
0.4 7.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 6.7 GO:0030425 dendrite(GO:0030425)
0.0 6.5 GO:0000139 Golgi membrane(GO:0000139)
0.2 6.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 6.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.4 6.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 6.0 GO:0071564 npBAF complex(GO:0071564)
1.4 5.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 5.7 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 239 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 17.5 GO:0045296 cadherin binding(GO:0045296)
0.1 12.8 GO:0017124 SH3 domain binding(GO:0017124)
3.4 10.3 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.5 10.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 10.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 7.1 GO:0017137 Rab GTPase binding(GO:0017137)
1.1 6.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 6.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 6.3 GO:0042287 MHC protein binding(GO:0042287)
0.3 6.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 6.1 GO:0051117 ATPase binding(GO:0051117)
1.5 6.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 5.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 4.8 GO:0008565 protein transporter activity(GO:0008565)
1.2 4.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 4.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.8 4.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.7 4.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 4.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 4.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)