Motif ID: Gata2_Gata1

Z-value: 0.965

Transcription factors associated with Gata2_Gata1:

Gene SymbolEntrez IDGene Name
Gata1 ENSMUSG00000031162.8 Gata1
Gata2 ENSMUSG00000015053.8 Gata2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata1mm10_v2_chrX_-_7967817_79679100.601.3e-03Click!
Gata2mm10_v2_chr6_+_88198656_881986750.087.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gata2_Gata1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_32276400 13.086 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276893 10.525 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr3_-_154330543 6.316 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr13_-_116309639 5.914 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr2_-_153241402 3.222 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr2_+_103957976 3.102 ENSMUST00000156813.1
ENSMUST00000170926.1
Lmo2

LIM domain only 2

chr7_-_139582790 3.095 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr7_-_4522427 2.646 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr6_+_30541582 2.544 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr17_-_84682932 2.519 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr13_+_38345716 2.514 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr17_+_36869567 2.425 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chrX_+_150547375 2.350 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr3_-_84479418 2.177 ENSMUST00000091002.1
Fhdc1
FH2 domain containing 1
chr4_+_11579647 2.049 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr15_-_103251465 1.806 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr8_+_34115030 1.794 ENSMUST00000095345.3
Mboat4
membrane bound O-acyltransferase domain containing 4
chr9_-_44342332 1.782 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr2_+_169632996 1.764 ENSMUST00000109159.2
Tshz2
teashirt zinc finger family member 2
chr7_-_4522794 1.679 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr4_-_59438633 1.658 ENSMUST00000040166.7
ENSMUST00000107544.1
Susd1

sushi domain containing 1

chr3_+_135825788 1.576 ENSMUST00000167390.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr9_-_32541589 1.572 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr4_+_41760454 1.553 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr7_-_99238564 1.547 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr2_+_169633517 1.528 ENSMUST00000109157.1
Tshz2
teashirt zinc finger family member 2
chr10_+_80019621 1.526 ENSMUST00000043311.6
Hmha1
histocompatibility (minor) HA-1
chr2_-_121037048 1.472 ENSMUST00000102490.3
Epb4.2
erythrocyte protein band 4.2
chrX_-_107403295 1.471 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr10_-_26078987 1.457 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chr3_-_63851251 1.363 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr11_+_90030295 1.356 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr12_-_10900296 1.315 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr11_-_64436653 1.290 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr7_-_100662315 1.269 ENSMUST00000151123.1
ENSMUST00000107047.2
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr7_+_110627650 1.208 ENSMUST00000033054.8
Adm
adrenomedullin
chr4_-_46404224 1.176 ENSMUST00000107764.2
Hemgn
hemogen
chr14_-_54577578 1.151 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr1_+_6730051 1.124 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr15_-_83170168 1.110 ENSMUST00000162834.1
Cyb5r3
cytochrome b5 reductase 3
chr19_-_7019423 1.094 ENSMUST00000040772.8
Fermt3
fermitin family homolog 3 (Drosophila)
chr19_-_42202150 1.060 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr15_-_83170498 1.044 ENSMUST00000162178.1
Cyb5r3
cytochrome b5 reductase 3
chr3_+_106113229 0.927 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr2_+_72476159 0.923 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr15_-_50890396 0.911 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr7_-_100662414 0.882 ENSMUST00000079176.6
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr17_+_71204647 0.869 ENSMUST00000126681.1
Lpin2
lipin 2
chr4_+_134864536 0.816 ENSMUST00000030627.7
Rhd
Rh blood group, D antigen
chr6_+_125552948 0.791 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr18_+_57142782 0.788 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr3_+_135826075 0.787 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr5_-_125294107 0.736 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr5_+_42067960 0.725 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr11_-_94242701 0.712 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr1_+_6730135 0.704 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr2_+_164403194 0.696 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr9_-_21963568 0.691 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr3_-_94473591 0.656 ENSMUST00000029785.3
Riiad1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr1_+_75450699 0.653 ENSMUST00000037708.9
Asic4
acid-sensing (proton-gated) ion channel family member 4
chr6_+_15185456 0.606 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr4_-_119190005 0.603 ENSMUST00000138395.1
ENSMUST00000156746.1
Ermap

erythroblast membrane-associated protein

chr1_+_75450436 0.601 ENSMUST00000113577.1
Asic4
acid-sensing (proton-gated) ion channel family member 4
chr8_+_84901928 0.589 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr2_+_70474923 0.570 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr6_+_15185203 0.561 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr11_-_102469839 0.559 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr2_+_26583858 0.551 ENSMUST00000100290.5
ENSMUST00000102907.5
Egfl7

EGF-like domain 7

chr2_+_85037212 0.538 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr14_-_34503323 0.534 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr19_+_24875679 0.528 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr6_-_71632897 0.515 ENSMUST00000065509.4
Kdm3a
lysine (K)-specific demethylase 3A
chr11_+_95337012 0.502 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr15_+_76904070 0.500 ENSMUST00000004072.8
Rpl8
ribosomal protein L8
chr4_+_117096049 0.500 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr14_+_66784523 0.497 ENSMUST00000071522.2
Gm10032
predicted gene 10032
chr3_-_146839365 0.492 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr14_+_45329815 0.468 ENSMUST00000022380.7
Psmc6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr17_-_85688252 0.458 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr8_+_46490968 0.454 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr6_-_122856151 0.453 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr8_+_84908560 0.446 ENSMUST00000003910.6
ENSMUST00000109744.1
Dnase2a

deoxyribonuclease II alpha

chr8_+_13037308 0.446 ENSMUST00000063820.5
ENSMUST00000033821.4
F10

coagulation factor X

chrX_+_73757069 0.423 ENSMUST00000002079.6
Plxnb3
plexin B3
chr3_-_138131356 0.417 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr2_-_25224653 0.396 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr10_-_13388830 0.395 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr15_-_98607611 0.375 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr9_+_109832998 0.375 ENSMUST00000119376.1
ENSMUST00000122343.1
Nme6

NME/NM23 nucleoside diphosphate kinase 6

chr8_+_84908680 0.371 ENSMUST00000145292.1
Dnase2a
deoxyribonuclease II alpha
chr16_-_44016387 0.364 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr1_+_45311538 0.363 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr19_-_43524462 0.360 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr3_+_89136133 0.350 ENSMUST00000047111.6
Pklr
pyruvate kinase liver and red blood cell
chr2_+_72476225 0.322 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr2_+_85037448 0.311 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr19_-_10482874 0.292 ENSMUST00000038842.3
Ppp1r32
protein phosphatase 1, regulatory subunit 32
chr11_-_53707269 0.287 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)

chr1_+_165788681 0.274 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr9_+_44069421 0.262 ENSMUST00000114830.2
Usp2
ubiquitin specific peptidase 2
chr17_+_46650328 0.260 ENSMUST00000043464.7
Cul7
cullin 7
chr7_+_110773658 0.257 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr15_+_80623499 0.257 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr18_-_43477764 0.250 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr13_-_91388079 0.249 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr11_+_73047783 0.247 ENSMUST00000021135.3
1200014J11Rik
RIKEN cDNA 1200014J11 gene
chr14_-_54653616 0.243 ENSMUST00000126166.1
ENSMUST00000141453.1
ENSMUST00000150371.1
ENSMUST00000123875.1
ENSMUST00000022794.7
ENSMUST00000148754.3
Acin1





apoptotic chromatin condensation inducer 1





chr3_+_79884496 0.238 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr5_+_24364804 0.237 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr1_+_135818593 0.225 ENSMUST00000038760.8
Lad1
ladinin
chr16_-_64786321 0.224 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr11_-_5898771 0.221 ENSMUST00000102921.3
Myl7
myosin, light polypeptide 7, regulatory
chrX_-_18461371 0.217 ENSMUST00000044188.4
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr5_-_121836852 0.209 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr8_+_84908731 0.205 ENSMUST00000134569.1
Dnase2a
deoxyribonuclease II alpha
chr3_+_90072641 0.205 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr1_-_82586781 0.202 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr9_+_44379536 0.191 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr11_+_87760533 0.185 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr2_-_77170592 0.183 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr5_+_64812336 0.180 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr1_+_165788746 0.179 ENSMUST00000161559.2
Cd247
CD247 antigen
chr9_+_44379490 0.178 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr2_+_84980458 0.175 ENSMUST00000028467.5
Prg2
proteoglycan 2, bone marrow
chr4_+_124802543 0.156 ENSMUST00000138807.1
ENSMUST00000030723.2
ENSMUST00000175875.1
Mtf1


metal response element binding transcription factor 1


chr10_+_90576708 0.156 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chrX_+_99975570 0.154 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr13_+_56703504 0.150 ENSMUST00000109874.1
Smad5
SMAD family member 5
chr11_+_118428493 0.145 ENSMUST00000017590.2
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr10_-_115185015 0.141 ENSMUST00000006949.8
Tph2
tryptophan hydroxylase 2
chr2_-_26246707 0.124 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr8_+_4325205 0.123 ENSMUST00000127460.1
ENSMUST00000136191.1
ENSMUST00000069762.9
ENSMUST00000098949.4
Ccl25

Ccl25

chemokine (C-C motif) ligand 25

chemokine (C-C motif) ligand 25

chr13_+_56702983 0.117 ENSMUST00000069557.7
ENSMUST00000109876.1
Smad5

SMAD family member 5

chr11_-_26591729 0.115 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr6_-_136941494 0.104 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr3_+_79885930 0.100 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr7_-_98112618 0.097 ENSMUST00000153657.1
Myo7a
myosin VIIA
chr11_+_70639118 0.094 ENSMUST00000055184.6
ENSMUST00000108551.2
Gp1ba

glycoprotein 1b, alpha polypeptide

chr3_+_133338936 0.094 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr5_+_64159429 0.068 ENSMUST00000043893.6
Tbc1d1
TBC1 domain family, member 1
chr9_-_44713196 0.058 ENSMUST00000144251.1
ENSMUST00000156918.1
Phldb1

pleckstrin homology-like domain, family B, member 1

chr11_+_118428203 0.055 ENSMUST00000124861.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr11_+_29130733 0.049 ENSMUST00000020756.8
Pnpt1
polyribonucleotide nucleotidyltransferase 1
chr8_+_105636509 0.042 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr3_+_89136572 0.040 ENSMUST00000107482.3
ENSMUST00000127058.1
Pklr

pyruvate kinase liver and red blood cell

chr6_-_136941694 0.036 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr7_-_141655319 0.034 ENSMUST00000062451.7
Muc6
mucin 6, gastric
chr10_+_61648552 0.033 ENSMUST00000020286.6
Ppa1
pyrophosphatase (inorganic) 1
chr16_+_43503607 0.028 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr13_-_8871696 0.022 ENSMUST00000054251.6
ENSMUST00000176813.1
Wdr37

WD repeat domain 37

chrX_+_10485121 0.011 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr1_-_14310198 0.008 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr1_+_75549581 0.007 ENSMUST00000154101.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr10_+_53337686 0.002 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr10_+_5593718 0.002 ENSMUST00000051809.8
Myct1
myc target 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 23.6 GO:0015671 oxygen transport(GO:0015671)
2.0 5.9 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.8 2.5 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.7 4.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.4 3.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.4 2.5 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.4 1.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.3 2.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 1.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 1.5 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 3.1 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.2 2.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 3.6 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.2 1.9 GO:0006071 glycerol metabolic process(GO:0006071)
0.2 1.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.2 1.8 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.2 1.8 GO:0018065 protein-cofactor linkage(GO:0018065)
0.2 0.5 GO:0048352 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352)
0.2 0.5 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.2 0.8 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 2.2 GO:0046697 decidualization(GO:0046697)
0.2 1.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 2.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.5 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.1 0.4 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 1.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 4.6 GO:0021884 forebrain neuron development(GO:0021884)
0.1 1.0 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.6 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.5 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 2.2 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.9 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0006586 tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 1.8 GO:0006497 protein lipidation(GO:0006497)
0.0 0.0 GO:0035928 mitochondrial RNA 3'-end processing(GO:0000965) RNA 5'-end processing(GO:0000966) rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 1.4 GO:0030168 platelet activation(GO:0030168)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 1.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.1 GO:0048563 post-embryonic organ morphogenesis(GO:0048563) equilibrioception(GO:0050957)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 23.6 GO:0005833 hemoglobin complex(GO:0005833)
1.1 6.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.9 4.3 GO:0005861 troponin complex(GO:0005861)
0.3 2.5 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.2 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0012506 vesicle membrane(GO:0012506)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.8 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 4.5 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 23.6 GO:0005344 oxygen transporter activity(GO:0005344)
1.4 4.3 GO:0030172 troponin C binding(GO:0030172)
0.5 1.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.4 1.6 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 1.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 1.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.3 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 2.5 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 2.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 8.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 0.5 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108)
0.2 2.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 0.5 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.2 0.5 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.1 2.3 GO:0016594 glycine binding(GO:0016594)
0.1 2.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.1 1.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.8 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 2.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.8 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 1.3 GO:0005272 sodium channel activity(GO:0005272)
0.0 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 3.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)