Motif ID: Gata3

Z-value: 1.251


Transcription factors associated with Gata3:

Gene SymbolEntrez IDGene Name
Gata3 ENSMUSG00000015619.10 Gata3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata3mm10_v2_chr2_-_9890026_98900350.301.3e-01Click!


Activity profile for motif Gata3.

activity profile for motif Gata3


Sorted Z-values histogram for motif Gata3

Sorted Z-values for motif Gata3



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_141874870 8.296 ENSMUST00000182079.1
Gm15294
predicted gene 15294
chr1_-_45890078 7.436 ENSMUST00000183590.1
Gm5269
predicted gene 5269
chr17_-_8566869 5.395 ENSMUST00000184183.1
Gm17087
predicted gene 17087
chr16_-_23890805 5.197 ENSMUST00000004480.3
Sst
somatostatin
chr19_-_50030735 4.672 ENSMUST00000071866.1
Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr1_-_16770138 4.376 ENSMUST00000071842.8
Gm5828
predicted gene 5828
chr1_-_52091066 3.865 ENSMUST00000105087.1
Gm3940
predicted gene 3940
chr13_-_21501418 3.482 ENSMUST00000044043.2
Gm11273
predicted gene 11273
chr11_+_58948890 3.472 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr11_+_94741782 2.960 ENSMUST00000021240.6
Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr6_-_55681257 2.786 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr11_-_72489904 2.668 ENSMUST00000045303.3
Spns2
spinster homolog 2
chr13_+_23574381 2.641 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr4_+_42158092 2.501 ENSMUST00000098122.2
Gm13306
predicted gene 13306
chr10_-_81472859 2.440 ENSMUST00000147524.1
ENSMUST00000119060.1
Celf5

CUGBP, Elav-like family member 5

chr13_-_21833575 2.436 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr18_-_34931931 2.426 ENSMUST00000180351.1
Etf1
eukaryotic translation termination factor 1
chr3_-_50443603 2.372 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr13_-_21753851 2.337 ENSMUST00000074752.2
Hist1h2ak
histone cluster 1, H2ak
chr18_+_35536539 2.318 ENSMUST00000081864.3
Gm5239
predicted pseudogene 5239

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 306 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 GO:0006342 chromatin silencing(GO:0006342)
0.2 5.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 4.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 4.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.8 3.3 GO:0007412 axon target recognition(GO:0007412)
0.5 3.3 GO:0032796 uropod organization(GO:0032796)
0.6 2.9 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 2.9 GO:0006334 nucleosome assembly(GO:0006334)
0.4 2.8 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.3 2.8 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.5 2.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 2.7 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.4 2.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 2.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.4 2.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 2.4 GO:0042073 intraciliary transport(GO:0042073)
0.2 2.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 2.2 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.0 2.2 GO:0007612 learning(GO:0007612)
0.5 2.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 138 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 7.4 GO:0043025 neuronal cell body(GO:0043025)
0.1 6.3 GO:0000786 nucleosome(GO:0000786)
0.0 6.1 GO:0060076 excitatory synapse(GO:0060076)
0.5 5.1 GO:0045298 tubulin complex(GO:0045298)
0.1 4.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.6 GO:0008021 synaptic vesicle(GO:0008021)
0.3 3.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 3.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 3.0 GO:0031091 platelet alpha granule(GO:0031091)
0.1 3.0 GO:0030673 axolemma(GO:0030673)
0.1 2.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.6 GO:0043204 perikaryon(GO:0043204)
0.0 2.5 GO:0055037 recycling endosome(GO:0055037)
0.5 2.4 GO:0030314 junctional membrane complex(GO:0030314)
0.1 2.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 190 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 5.5 GO:0005179 hormone activity(GO:0005179)
0.1 5.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 4.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 4.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 3.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.3 3.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 3.1 GO:0019534 toxin transporter activity(GO:0019534)
0.5 2.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.6 2.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 2.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 2.2 GO:0019905 syntaxin binding(GO:0019905)
0.5 2.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.5 2.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.5 2.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.7 2.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.2 2.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)