Motif ID: Gata6

Z-value: 0.268


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_154330543 0.676 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr10_-_86732409 0.576 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr9_-_29963112 0.557 ENSMUST00000075069.4
 Ntm
neurotrimin
chr11_+_67586675 0.526 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr1_+_152954966 0.401 ENSMUST00000043313.8
 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr10_-_62342674 0.377 ENSMUST00000143179.1
ENSMUST00000130422.1
 Hk1

hexokinase 1

chr6_+_58833689 0.339 ENSMUST00000041401.8
 Herc3
hect domain and RLD 3
chr2_+_65930117 0.314 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr15_+_18818895 0.298 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr19_+_58670358 0.293 ENSMUST00000057270.7
 Pnlip
pancreatic lipase
chr4_+_13751297 0.289 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_86078070 0.244 ENSMUST00000032069.5
 Add2
adducin 2 (beta)
chr1_-_162866502 0.234 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr2_+_68104671 0.225 ENSMUST00000042456.3
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_+_58831748 0.217 ENSMUST00000126292.1
ENSMUST00000031823.5
 Herc3

hect domain and RLD 3

chr2_-_7396192 0.210 ENSMUST00000137733.2
 Celf2
CUGBP, Elav-like family member 2
chr1_+_45311538 0.209 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr11_+_3330781 0.203 ENSMUST00000136536.1
ENSMUST00000093399.4
 Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr5_+_76840597 0.201 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
 C530008M17Rik


RIKEN cDNA C530008M17 gene


chr1_-_173333503 0.200 ENSMUST00000038227.4
 Darc
Duffy blood group, chemokine receptor
chr2_-_7081207 0.190 ENSMUST00000114923.2
ENSMUST00000182706.1
 Celf2

CUGBP, Elav-like family member 2

chr5_-_111761697 0.184 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr4_-_46404224 0.167 ENSMUST00000107764.2
 Hemgn
hemogen
chr2_-_7395968 0.164 ENSMUST00000002176.6
 Celf2
CUGBP, Elav-like family member 2
chr6_-_38124568 0.163 ENSMUST00000040259.4
 Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr19_+_4711153 0.160 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr2_-_7081256 0.159 ENSMUST00000183209.1
 Celf2
CUGBP, Elav-like family member 2
chr2_-_7395879 0.157 ENSMUST00000182404.1
 Celf2
CUGBP, Elav-like family member 2
chr18_+_37300799 0.153 ENSMUST00000051754.1
 Pcdhb3
protocadherin beta 3
chr5_+_19907502 0.148 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_33087169 0.146 ENSMUST00000102810.3
 Garnl3
GTPase activating RANGAP domain-like 3
chr18_+_76059458 0.134 ENSMUST00000167921.1
 Zbtb7c
zinc finger and BTB domain containing 7C
chr2_-_33086366 0.126 ENSMUST00000049618.2
 Garnl3
GTPase activating RANGAP domain-like 3
chr17_-_33713372 0.124 ENSMUST00000173392.1
 March2
membrane-associated ring finger (C3HC4) 2
chr11_-_102365111 0.120 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr12_+_95692212 0.106 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chrX_+_10485121 0.096 ENSMUST00000076354.6
ENSMUST00000115526.1
 Tspan7

tetraspanin 7

chrX_-_37110257 0.093 ENSMUST00000076265.6
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr3_-_59262825 0.092 ENSMUST00000050360.7
 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr9_+_66350465 0.076 ENSMUST00000042824.6
 Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr8_-_122699066 0.069 ENSMUST00000127984.1
 Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr11_+_4883186 0.062 ENSMUST00000139737.1
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr11_+_87581041 0.055 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
 Sept4


septin 4


chr7_-_139582790 0.054 ENSMUST00000106095.2
 Nkx6-2
NK6 homeobox 2
chr10_+_40883469 0.045 ENSMUST00000019975.7
 Wasf1
WAS protein family, member 1
chr2_-_77170592 0.039 ENSMUST00000164114.2
ENSMUST00000049544.7
 Ccdc141

coiled-coil domain containing 141

chr11_+_4986824 0.039 ENSMUST00000009234.9
ENSMUST00000109897.1
 Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr7_+_119900099 0.034 ENSMUST00000106516.1
 Lyrm1
LYR motif containing 1
chr11_+_95712673 0.033 ENSMUST00000107717.1
 Zfp652
zinc finger protein 652
chr3_-_20242173 0.032 ENSMUST00000001921.1
 Cpa3
carboxypeptidase A3, mast cell
chr1_-_25829511 0.030 ENSMUST00000135518.1
ENSMUST00000151309.1
 Bai3

brain-specific angiogenesis inhibitor 3

chr16_+_36041184 0.030 ENSMUST00000042203.8
 Wdr5b
WD repeat domain 5B
chr17_+_34604819 0.027 ENSMUST00000173242.1
 Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr2_+_172370658 0.027 ENSMUST00000151511.1
ENSMUST00000116375.1
 Cstf1

cleavage stimulation factor, 3' pre-RNA, subunit 1

chr16_-_34262945 0.025 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr11_+_98026918 0.024 ENSMUST00000017548.6
 Rpl19
ribosomal protein L19
chr5_-_30461902 0.023 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
 Otof



otoferlin



chr11_-_103697898 0.021 ENSMUST00000021329.7
 Gosr2
golgi SNAP receptor complex member 2
chr11_-_53707269 0.020 ENSMUST00000124352.1
ENSMUST00000020649.7
 Rad50

RAD50 homolog (S. cerevisiae)

chr13_-_91388079 0.019 ENSMUST00000181054.1
 A830009L08Rik
RIKEN cDNA A830009L08 gene
chr8_-_64205970 0.019 ENSMUST00000066166.4
 Tll1
tolloid-like
chr10_+_53337686 0.018 ENSMUST00000046221.6
ENSMUST00000163319.1
 Pln

phospholamban

chr15_-_83170168 0.018 ENSMUST00000162834.1
 Cyb5r3
cytochrome b5 reductase 3
chr9_-_106887000 0.015 ENSMUST00000055843.7
 Rbm15b
RNA binding motif protein 15B
chr5_-_125294107 0.014 ENSMUST00000127148.1
 Scarb1
scavenger receptor class B, member 1
chr5_+_121777929 0.014 ENSMUST00000160821.1
 Atxn2
ataxin 2
chr9_-_65827544 0.008 ENSMUST00000159109.1
 Zfp609
zinc finger protein 609
chr16_-_46010212 0.007 ENSMUST00000130481.1
 Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr15_-_83170498 0.006 ENSMUST00000162178.1
 Cyb5r3
cytochrome b5 reductase 3
chr6_-_136875794 0.005 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr11_+_98026695 0.003 ENSMUST00000092425.4
 Rpl19
ribosomal protein L19
chr7_+_28833975 0.002 ENSMUST00000066723.8
 Lgals4
lectin, galactose binding, soluble 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.4 GO:0010359 regulation of anion channel activity(GO:0010359)
0.0 0.3 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.7 GO:0021884 forebrain neuron development(GO:0021884)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0097227 sperm annulus(GO:0097227)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.4 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)