Motif ID: Gfi1_Gfi1b

Z-value: 1.610

Transcription factors associated with Gfi1_Gfi1b:

Gene SymbolEntrez IDGene Name
Gfi1 ENSMUSG00000029275.11 Gfi1
Gfi1b ENSMUSG00000026815.8 Gfi1b



Activity profile for motif Gfi1_Gfi1b.

activity profile for motif Gfi1_Gfi1b


Sorted Z-values histogram for motif Gfi1_Gfi1b

Sorted Z-values for motif Gfi1_Gfi1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Gfi1_Gfi1b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 18.186 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr16_-_26989974 10.323 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr13_-_71963713 6.918 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr7_+_62376979 6.714 ENSMUST00000080403.5
 Magel2
melanoma antigen, family L, 2
chr11_-_84525514 5.203 ENSMUST00000018842.7
 Lhx1
LIM homeobox protein 1
chr19_+_55741810 4.851 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr10_-_127341583 4.803 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr2_+_109917639 4.133 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr13_+_35659856 4.008 ENSMUST00000075220.6
 Cdyl
chromodomain protein, Y chromosome-like
chr12_+_109544498 3.933 ENSMUST00000126289.1
 Meg3
maternally expressed 3
chr3_-_154330543 3.803 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr11_+_44617310 3.737 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr11_+_84525669 3.663 ENSMUST00000126072.1
ENSMUST00000128121.1
 1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr5_+_75075464 3.626 ENSMUST00000160104.1
ENSMUST00000040477.3
 Gsx2

GS homeobox 2

chr10_+_127759780 3.592 ENSMUST00000128247.1
 RP23-386P10.11
Protein Rdh9
chr11_+_84525647 3.568 ENSMUST00000134800.1
 1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr8_-_91801948 3.554 ENSMUST00000175795.1
 Irx3
Iroquois related homeobox 3 (Drosophila)
chr7_-_62464505 3.505 ENSMUST00000094339.2
 Peg12
paternally expressed 12
chr8_+_106935720 3.345 ENSMUST00000047425.3
 Sntb2
syntrophin, basic 2
chr9_+_3005125 3.342 ENSMUST00000179881.1
 Gm11168
predicted gene 11168

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 204 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 18.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 12.2 GO:0006270 DNA replication initiation(GO:0006270)
0.3 8.1 GO:0008340 determination of adult lifespan(GO:0008340)
1.9 7.5 GO:2000768 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.3 6.9 GO:0051127 positive regulation of actin nucleation(GO:0051127)
1.3 5.2 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.4 5.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.6 4.9 GO:0048625 myoblast fate commitment(GO:0048625)
1.2 4.8 GO:0060032 notochord regression(GO:0060032)
0.1 4.2 GO:1902476 chloride transmembrane transport(GO:1902476)
1.4 4.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.4 4.1 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 3.9 GO:0000578 embryonic axis specification(GO:0000578)
0.0 3.9 GO:0008360 regulation of cell shape(GO:0008360)
0.1 3.8 GO:0021884 forebrain neuron development(GO:0021884)
0.1 3.2 GO:0071398 cellular response to fatty acid(GO:0071398)
0.1 3.1 GO:0032611 interleukin-1 beta production(GO:0032611)
0.4 3.0 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 2.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.9 2.7 GO:0097274 urea homeostasis(GO:0097274)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 84 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.1 GO:0000776 kinetochore(GO:0000776)
0.2 6.7 GO:0030904 retromer complex(GO:0030904)
0.5 4.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.4 4.8 GO:0097542 ciliary tip(GO:0097542)
0.1 4.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.4 4.1 GO:0005588 collagen type V trimer(GO:0005588)
0.6 3.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 3.8 GO:0005667 transcription factor complex(GO:0005667)
0.4 3.1 GO:0033269 internode region of axon(GO:0033269)
0.0 2.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 2.7 GO:0045120 pronucleus(GO:0045120)
0.0 2.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.4 GO:0005876 spindle microtubule(GO:0005876)
0.8 2.3 GO:0071914 prominosome(GO:0071914)
0.0 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.3 2.0 GO:0001520 outer dense fiber(GO:0001520) meiotic spindle(GO:0072687)
0.1 2.0 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 2.0 GO:0002102 podosome(GO:0002102)
0.0 2.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.9 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 33.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 22.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 13.0 GO:0003682 chromatin binding(GO:0003682)
0.0 6.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 6.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 5.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 5.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 4.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 4.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 4.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 4.0 GO:0003779 actin binding(GO:0003779)
0.3 3.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 3.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 3.1 GO:0042805 actinin binding(GO:0042805)
0.0 3.1 GO:0051015 actin filament binding(GO:0051015)
0.1 2.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 2.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.5 GO:0030371 translation repressor activity(GO:0030371)
0.6 2.4 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)