Motif ID: Gli3_Zic1

Z-value: 1.537

Transcription factors associated with Gli3_Zic1:

Gene SymbolEntrez IDGene Name
Gli3 ENSMUSG00000021318.9 Gli3
Zic1 ENSMUSG00000032368.8 Zic1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli3mm10_v2_chr13_+_15463837_15463980-0.831.5e-07Click!
Zic1mm10_v2_chr9_-_91365756_91365774-0.281.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gli3_Zic1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_50752758 7.158 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr16_+_91269759 6.569 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr4_+_124657646 6.415 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr2_-_29253001 5.411 ENSMUST00000071201.4
Ntng2
netrin G2
chr4_-_148130678 5.392 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr7_+_99268338 5.366 ENSMUST00000107100.2
Map6
microtubule-associated protein 6
chr6_-_101377897 5.213 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr11_-_42000284 5.188 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr2_-_36104060 5.075 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr11_-_42000532 5.042 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr8_+_70501116 5.041 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr15_-_95528228 5.019 ENSMUST00000075275.2
Nell2
NEL-like 2
chr1_-_133801031 4.990 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr6_+_17463749 4.129 ENSMUST00000115443.1
Met
met proto-oncogene
chr17_-_24209377 3.715 ENSMUST00000024931.4
Ntn3
netrin 3
chr7_-_142657466 3.701 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr8_+_76902277 3.581 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr6_+_110645572 3.532 ENSMUST00000071076.6
ENSMUST00000172951.1
Grm7

glutamate receptor, metabotropic 7

chr11_-_116654245 3.461 ENSMUST00000021166.5
Cygb
cytoglobin
chr4_-_136956784 3.350 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr3_+_68494208 3.316 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr4_+_133011506 3.220 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr6_-_113531575 3.219 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr4_+_48045144 3.205 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr14_+_55560480 3.158 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr8_-_105966038 3.140 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr14_-_55560340 3.103 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr16_-_28445227 2.970 ENSMUST00000100024.1
Fgf12
fibroblast growth factor 12
chr15_-_95528702 2.927 ENSMUST00000166170.1
Nell2
NEL-like 2
chr17_-_68004075 2.886 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr6_-_101377342 2.880 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr1_-_56972437 2.789 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr12_+_73997749 2.642 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr18_+_86394952 2.537 ENSMUST00000058829.2
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr11_-_42182163 2.482 ENSMUST00000153147.1
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr6_+_17463826 2.472 ENSMUST00000140070.1
Met
met proto-oncogene
chr13_-_54611274 2.467 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr8_+_54954728 2.414 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr4_-_68954351 2.374 ENSMUST00000030036.5
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr7_-_19698383 2.339 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr1_-_180483410 2.326 ENSMUST00000136521.1
ENSMUST00000179826.1
6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr15_-_78718113 2.312 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr14_+_55560904 2.311 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chrX_-_16911774 2.310 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr7_+_5057161 2.307 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr7_+_99535439 2.303 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr6_+_17463927 2.287 ENSMUST00000115442.1
Met
met proto-oncogene
chr7_+_5056856 2.270 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr19_+_4711153 2.267 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr17_+_37050631 2.258 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr13_+_54949388 2.251 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr4_+_144893077 2.239 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr14_-_30353468 2.228 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr7_+_5056706 2.188 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr1_-_69108039 2.171 ENSMUST00000121473.1
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr7_-_84605819 2.171 ENSMUST00000032865.9
Fah
fumarylacetoacetate hydrolase
chr11_+_101246405 2.041 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr13_-_54611332 2.041 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr14_+_55561060 2.019 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr19_-_4698315 1.982 ENSMUST00000096325.3
Gm960
predicted gene 960
chr1_-_134234492 1.945 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr6_+_86195214 1.915 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr7_-_111779963 1.890 ENSMUST00000049430.8
ENSMUST00000106663.1
Galnt18

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18

chrX_-_7574120 1.884 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f


protein phosphatase 1, regulatory (inhibitor) subunit 3F


chrX_+_163908982 1.872 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr6_-_125494754 1.853 ENSMUST00000032492.8
Cd9
CD9 antigen
chr18_-_43373248 1.845 ENSMUST00000118043.1
Dpysl3
dihydropyrimidinase-like 3
chr5_+_26817357 1.783 ENSMUST00000071500.6
Dpp6
dipeptidylpeptidase 6
chr1_-_134235420 1.759 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr18_-_38601268 1.740 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr5_+_5573952 1.740 ENSMUST00000101627.2
Gm8773
predicted gene 8773
chrX_+_101299143 1.738 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
Nlgn3


neuroligin 3


chr2_+_70562007 1.722 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr11_-_60352869 1.717 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
Tom1l2





target of myb1-like 2 (chicken)





chr11_-_70229677 1.705 ENSMUST00000153449.1
ENSMUST00000000326.5
Bcl6b

B cell CLL/lymphoma 6, member B

chr6_-_28830345 1.701 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr15_-_100584075 1.699 ENSMUST00000184908.1
POU6F1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chr6_-_118780324 1.666 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr2_+_35282380 1.646 ENSMUST00000028239.6
Gsn
gelsolin
chr7_+_57591147 1.641 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr10_+_127165118 1.626 ENSMUST00000006914.9
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr5_+_30588078 1.619 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr7_+_128246812 1.599 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chrX_+_101299207 1.595 ENSMUST00000065858.2
Nlgn3
neuroligin 3
chr9_-_108190352 1.594 ENSMUST00000035208.7
Bsn
bassoon
chr9_-_58158498 1.585 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr2_+_158667119 1.584 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr13_+_54575020 1.578 ENSMUST00000156024.1
Arl10
ADP-ribosylation factor-like 10
chr8_-_105637403 1.576 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chrX_+_155262443 1.575 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr1_-_22805994 1.575 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr11_+_70647258 1.568 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr8_-_69887687 1.563 ENSMUST00000057831.7
Cilp2
cartilage intermediate layer protein 2
chr16_+_43503607 1.542 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr9_-_56418023 1.537 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr13_+_54575008 1.438 ENSMUST00000026988.4
Arl10
ADP-ribosylation factor-like 10
chr7_+_128246953 1.431 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chrX_-_150812715 1.431 ENSMUST00000112697.3
Maged2
melanoma antigen, family D, 2
chr8_-_85840877 1.430 ENSMUST00000034140.7
Itfg1
integrin alpha FG-GAP repeat containing 1
chr5_-_34187670 1.427 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr10_-_127341583 1.416 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chrX_+_159697308 1.400 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr4_-_151108244 1.388 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr8_-_105637350 1.369 ENSMUST00000182863.1
Gm5914
predicted gene 5914
chr5_-_118244861 1.356 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr11_+_73018986 1.340 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr11_+_69765970 1.332 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr6_-_85502980 1.315 ENSMUST00000159062.1
Fbxo41
F-box protein 41
chr4_+_42949814 1.305 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr6_+_17491216 1.304 ENSMUST00000080469.5
Met
met proto-oncogene
chr8_-_41041828 1.302 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr8_-_71723308 1.290 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr13_+_118714678 1.283 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr12_+_109545390 1.283 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr11_+_69095217 1.281 ENSMUST00000101004.2
Per1
period circadian clock 1
chr8_+_11728105 1.274 ENSMUST00000110909.2
ENSMUST00000033908.6
Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

chr19_-_6084679 1.267 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr15_-_53902472 1.265 ENSMUST00000078673.6
Samd12
sterile alpha motif domain containing 12
chr6_-_85502858 1.244 ENSMUST00000161546.1
ENSMUST00000161078.1
Fbxo41

F-box protein 41

chr5_+_71699918 1.235 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr17_+_37045963 1.231 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_+_23107413 1.219 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chrX_+_74329058 1.219 ENSMUST00000004326.3
Plxna3
plexin A3
chr7_+_25267669 1.199 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr3_+_31149934 1.156 ENSMUST00000046174.6
Cldn11
claudin 11
chr8_-_105295934 1.149 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr3_+_28263205 1.147 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr10_+_69533761 1.141 ENSMUST00000182884.1
Ank3
ankyrin 3, epithelial
chr11_-_116359060 1.132 ENSMUST00000149147.1
Rnf157
ring finger protein 157
chr13_-_49320219 1.114 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr3_-_89245159 1.106 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr16_+_20733104 1.092 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr10_+_40349265 1.062 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr16_-_30550560 1.061 ENSMUST00000140402.1
Tmem44
transmembrane protein 44
chr10_-_64090265 1.056 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_-_64090241 1.036 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr15_-_98953541 1.021 ENSMUST00000097014.5
Tuba1a
tubulin, alpha 1A
chr3_+_105452326 1.015 ENSMUST00000098761.3
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr2_-_144527341 1.011 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr6_-_115251839 0.995 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr3_-_89245005 0.993 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr2_-_45110336 0.985 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr5_+_143370092 0.973 ENSMUST00000120825.1
Grid2ip
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chr11_-_118248507 0.959 ENSMUST00000017276.7
Cyth1
cytohesin 1
chr11_+_101246960 0.956 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr11_+_87760533 0.953 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr10_+_69534208 0.952 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr10_+_69533803 0.952 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
Ank3


ankyrin 3, epithelial


chr17_+_37045980 0.946 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr17_+_35135174 0.944 ENSMUST00000166426.2
ENSMUST00000025250.7
Bag6

BCL2-associated athanogene 6

chrX_+_161717498 0.939 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr7_+_3390629 0.929 ENSMUST00000182222.1
Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chrX_-_150812932 0.923 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chr4_+_123183456 0.921 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr6_-_119330723 0.921 ENSMUST00000068351.7
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr2_-_155945282 0.910 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chr4_-_120287349 0.904 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr9_+_100643755 0.900 ENSMUST00000133388.1
Stag1
stromal antigen 1
chrX_+_73064787 0.895 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr9_+_21165714 0.893 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr2_+_164879358 0.893 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr5_+_137778849 0.891 ENSMUST00000126126.1
ENSMUST00000031739.4
Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr7_-_142656018 0.891 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr11_-_118248590 0.890 ENSMUST00000106305.2
Cyth1
cytohesin 1
chr4_+_117096049 0.889 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr1_-_153900198 0.881 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr4_+_42950369 0.878 ENSMUST00000084662.5
Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr10_+_80249106 0.872 ENSMUST00000105364.1
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr11_-_69369377 0.867 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr11_+_51289920 0.867 ENSMUST00000102765.2
Col23a1
collagen, type XXIII, alpha 1
chr9_+_100643448 0.860 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1

chr9_+_100643605 0.858 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr12_+_4234023 0.855 ENSMUST00000179139.1
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr17_+_35135196 0.845 ENSMUST00000172571.1
ENSMUST00000173491.1
Bag6

BCL2-associated athanogene 6

chr17_-_24650270 0.843 ENSMUST00000002572.4
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr2_+_118111876 0.839 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr17_+_56326045 0.835 ENSMUST00000139679.1
ENSMUST00000025036.4
ENSMUST00000086835.5
Kdm4b


lysine (K)-specific demethylase 4B


chr7_-_19665005 0.833 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr5_+_138995038 0.832 ENSMUST00000100518.2
6330403L08Rik
RIKEN cDNA 6330403L08 gene
chr19_+_5740885 0.825 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr12_+_3365108 0.824 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr1_-_165460430 0.823 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr15_-_99820072 0.821 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr4_+_147940859 0.821 ENSMUST00000103232.1
2510039O18Rik
RIKEN cDNA 2510039O18 gene
chr10_+_80249441 0.820 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr7_-_80401707 0.804 ENSMUST00000120753.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr3_+_94478831 0.799 ENSMUST00000029784.5
Celf3
CUGBP, Elav-like family member 3
chr17_-_27204357 0.788 ENSMUST00000055117.7
Lemd2
LEM domain containing 2
chr8_+_23139030 0.785 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr18_+_22345089 0.780 ENSMUST00000120223.1
ENSMUST00000097655.3
Asxl3

additional sex combs like 3 (Drosophila)

chr19_-_32388462 0.768 ENSMUST00000099514.3
Sgms1
sphingomyelin synthase 1
chr1_-_155099630 0.763 ENSMUST00000055322.4
Ier5
immediate early response 5
chr7_+_65693447 0.760 ENSMUST00000143508.1
Tm2d3
TM2 domain containing 3
chr10_+_69534039 0.756 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr7_+_12881165 0.746 ENSMUST00000144578.1
Zfp128
zinc finger protein 128
chr5_-_38561658 0.731 ENSMUST00000005234.9
Wdr1
WD repeat domain 1
chr4_+_123233556 0.731 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chr16_-_91011308 0.724 ENSMUST00000121759.1
Synj1
synaptojanin 1
chr16_+_17561885 0.708 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr7_+_24370255 0.705 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
1.7 15.6 GO:0071420 cellular response to histamine(GO:0071420)
1.4 4.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
1.3 11.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.2 7.2 GO:0007021 tubulin complex assembly(GO:0007021)
1.1 3.2 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.9 5.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.8 5.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.8 3.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.8 2.3 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.7 2.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.7 2.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.7 7.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.7 2.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 3.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.7 3.5 GO:0015671 oxygen transport(GO:0015671)
0.7 2.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.7 4.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.6 4.4 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.6 3.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.6 2.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 1.6 GO:1903903 striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.5 1.6 GO:0016191 synaptic vesicle uncoating(GO:0016191) regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.4 3.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.4 1.7 GO:0086045 smooth muscle contraction involved in micturition(GO:0060083) membrane depolarization during AV node cell action potential(GO:0086045) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.4 1.6 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.4 1.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.4 2.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.4 2.9 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.4 1.4 GO:0060032 notochord regression(GO:0060032)
0.3 3.8 GO:0016322 neuron remodeling(GO:0016322)
0.3 3.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.6 GO:0030259 lipid glycosylation(GO:0030259)
0.3 1.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 1.0 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.3 1.9 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.3 3.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 1.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 2.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 1.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 4.4 GO:0001553 luteinization(GO:0001553)
0.3 0.8 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3 2.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.3 1.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 5.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.3 0.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 4.7 GO:0002076 osteoblast development(GO:0002076)
0.2 2.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.7 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 2.4 GO:0042711 maternal behavior(GO:0042711)
0.2 1.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 0.6 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.2 0.6 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.2 2.2 GO:0042572 retinol metabolic process(GO:0042572)
0.2 1.2 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.2 0.4 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 1.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2 3.6 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958)
0.2 0.7 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.2 1.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 0.5 GO:0070375 ERK5 cascade(GO:0070375)
0.2 2.1 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2 0.5 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.2 0.8 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2 0.5 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.2 1.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.4 GO:0045950 telomeric loop formation(GO:0031627) negative regulation of mitotic recombination(GO:0045950) negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 1.8 GO:0051601 exocyst localization(GO:0051601)
0.1 6.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.4 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 0.4 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.6 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.4 GO:1902724 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) positive regulation of metalloendopeptidase activity(GO:1904685)
0.1 0.8 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 0.4 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478)
0.1 1.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.7 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 1.0 GO:0071435 potassium ion export(GO:0071435)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.7 GO:0032796 uropod organization(GO:0032796)
0.1 0.5 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.4 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.1 0.4 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) positive regulation of hepatocyte proliferation(GO:2000347)
0.1 6.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 3.0 GO:2001258 negative regulation of cation channel activity(GO:2001258)
0.1 1.7 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.3 GO:0007521 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 5.4 GO:0032418 lysosome localization(GO:0032418)
0.1 3.7 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.6 GO:0036233 glycine import(GO:0036233)
0.1 0.7 GO:0099623 regulation of cardiac muscle cell membrane repolarization(GO:0099623)
0.1 5.4 GO:0008542 visual learning(GO:0008542)
0.1 0.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.9 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 6.6 GO:0048663 neuron fate commitment(GO:0048663)
0.1 0.4 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 0.4 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 6.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 2.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 2.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 1.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.4 GO:0042535 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 0.7 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.3 GO:0019042 viral latency(GO:0019042)
0.1 0.5 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 1.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.3 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.3 GO:0021940 regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 0.3 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.1 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.4 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 1.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.6 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 4.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 0.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.9 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.8 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.0 GO:0072235 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0 0.9 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 5.0 GO:0007416 synapse assembly(GO:0007416)
0.0 0.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.6 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 1.7 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.8 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.6 GO:0060384 innervation(GO:0060384)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 1.9 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.3 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.7 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.1 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.0 0.7 GO:0033198 response to ATP(GO:0033198)
0.0 0.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.3 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 1.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.6 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.5 GO:0070266 necroptotic process(GO:0070266)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 1.1 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.7 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.8 GO:0031529 ruffle organization(GO:0031529)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0035094 response to nicotine(GO:0035094)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.7 GO:0006457 protein folding(GO:0006457)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.5 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 1.8 GO:0006813 potassium ion transport(GO:0006813)
0.0 1.8 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.2 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.7 GO:0033674 positive regulation of kinase activity(GO:0033674)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0097512 cardiac myofibril(GO:0097512)
1.7 5.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.9 4.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.9 15.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.8 2.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.6 3.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.4 2.6 GO:0008091 spectrin(GO:0008091)
0.4 2.9 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.4 4.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 3.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 6.6 GO:0060077 inhibitory synapse(GO:0060077)
0.3 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.3 5.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 3.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 5.0 GO:0097228 sperm principal piece(GO:0097228)
0.2 8.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 4.3 GO:0030673 axolemma(GO:0030673)
0.2 1.3 GO:0000322 storage vacuole(GO:0000322)
0.2 10.1 GO:0009925 basal plasma membrane(GO:0009925)
0.2 1.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 5.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.7 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 2.3 GO:0031143 pseudopodium(GO:0031143)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.4 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.4 GO:0097542 ciliary tip(GO:0097542)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 1.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 7.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.6 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.8 GO:0000145 exocyst(GO:0000145)
0.1 2.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.5 GO:0045178 basal part of cell(GO:0045178)
0.1 5.7 GO:0043204 perikaryon(GO:0043204)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0033391 chromatoid body(GO:0033391)
0.0 1.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 8.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 3.5 GO:0030175 filopodium(GO:0030175)
0.0 1.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 4.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 4.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005902 microvillus(GO:0005902) actin-based cell projection(GO:0098858)
0.0 0.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 6.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0030017 sarcomere(GO:0030017)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 3.7 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.2 3.5 GO:0070905 serine binding(GO:0070905)
0.9 15.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.9 3.5 GO:0004096 catalase activity(GO:0004096)
0.8 2.3 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.8 2.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.7 4.4 GO:0016917 G-protein coupled GABA receptor activity(GO:0004965) GABA receptor activity(GO:0016917)
0.7 5.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.6 3.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.5 4.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 3.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.5 1.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.5 3.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 4.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.5 1.9 GO:2001069 glycogen binding(GO:2001069)
0.5 1.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 2.2 GO:0038132 neuregulin binding(GO:0038132)
0.4 3.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 5.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 3.0 GO:0048495 Roundabout binding(GO:0048495)
0.4 2.3 GO:0005042 netrin receptor activity(GO:0005042)
0.3 2.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 1.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 2.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 2.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 0.8 GO:0070052 collagen V binding(GO:0070052)
0.2 0.7 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 1.0 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.2 1.6 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.2 1.1 GO:0045545 syndecan binding(GO:0045545)
0.2 1.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 1.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 3.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 4.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.6 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108)
0.2 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 3.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.1 GO:0036122 BMP binding(GO:0036122)
0.2 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 3.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 5.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.2 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 0.5 GO:0032052 bile acid binding(GO:0032052)
0.2 3.0 GO:0015026 coreceptor activity(GO:0015026)
0.2 1.6 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 2.9 GO:0070628 proteasome binding(GO:0070628)
0.1 1.7 GO:0048038 quinone binding(GO:0048038)
0.1 0.4 GO:0003884 D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.7 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.7 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 6.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.6 GO:0015265 urea channel activity(GO:0015265)
0.1 0.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 3.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 1.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.9 GO:0030276 clathrin binding(GO:0030276)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 3.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.5 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 4.1 GO:0005262 calcium channel activity(GO:0005262)
0.1 5.4 GO:0008201 heparin binding(GO:0008201)
0.1 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 1.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 6.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.4 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 3.1 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 1.1 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 2.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 5.9 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.0 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0019239 deaminase activity(GO:0019239)
0.0 1.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0015491 cation:cation antiporter activity(GO:0015491)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.0 1.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)