Motif ID: Glis2

Z-value: 0.889


Transcription factors associated with Glis2:

Gene SymbolEntrez IDGene Name
Glis2 ENSMUSG00000014303.7 Glis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Glis2mm10_v2_chr16_+_4594683_45947350.213.1e-01Click!


Activity profile for motif Glis2.

activity profile for motif Glis2


Sorted Z-values histogram for motif Glis2

Sorted Z-values for motif Glis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Glis2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_66981279 4.823 ENSMUST00000162098.2
Shox2
short stature homeobox 2
chr3_+_87948666 4.483 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr8_-_91801547 4.434 ENSMUST00000093312.4
Irx3
Iroquois related homeobox 3 (Drosophila)
chr8_-_91801948 3.944 ENSMUST00000175795.1
Irx3
Iroquois related homeobox 3 (Drosophila)
chr19_+_55741810 3.658 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr4_+_115059507 2.795 ENSMUST00000162489.1
Tal1
T cell acute lymphocytic leukemia 1
chr7_-_103843154 2.085 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr5_+_136083916 1.543 ENSMUST00000042135.7
Rasa4
RAS p21 protein activator 4
chr5_+_136084022 1.425 ENSMUST00000100570.3
Rasa4
RAS p21 protein activator 4
chr1_-_172329261 1.419 ENSMUST00000062387.2
Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr8_-_87472576 1.356 ENSMUST00000034076.8
Cbln1
cerebellin 1 precursor protein
chr5_-_30105359 1.295 ENSMUST00000127749.3
3110082J24Rik
RIKEN cDNA 3110082J24 gene
chr2_-_57113053 1.208 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr8_+_58911755 1.169 ENSMUST00000062978.6
BC030500
cDNA sequence BC030500
chr2_-_57124003 1.144 ENSMUST00000112629.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr7_-_126704736 1.133 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr2_-_26294550 1.110 ENSMUST00000057224.3
4932418E24Rik
RIKEN cDNA 4932418E24 gene
chr3_+_130180882 0.996 ENSMUST00000106353.1
ENSMUST00000080335.4
Col25a1

collagen, type XXV, alpha 1

chr19_+_7268296 0.977 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr6_-_48840988 0.963 ENSMUST00000164733.1
Tmem176b
transmembrane protein 176B
chr5_+_30105161 0.914 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr4_+_148804420 0.908 ENSMUST00000094464.3
ENSMUST00000122222.1
Casz1

castor zinc finger 1

chr11_-_102230091 0.898 ENSMUST00000008999.5
Hdac5
histone deacetylase 5
chr2_-_54085542 0.869 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr19_-_58454435 0.868 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr11_-_102230127 0.865 ENSMUST00000107150.1
ENSMUST00000156337.1
ENSMUST00000107151.2
ENSMUST00000107152.2
Hdac5



histone deacetylase 5



chr1_-_84696182 0.843 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr5_-_137533297 0.812 ENSMUST00000111020.1
ENSMUST00000111023.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr11_-_101170327 0.790 ENSMUST00000123864.1
Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr5_+_115327125 0.768 ENSMUST00000031513.7
Srsf9
serine/arginine-rich splicing factor 9
chr10_+_84838143 0.762 ENSMUST00000095388.4
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr14_+_55854115 0.742 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr2_+_4976113 0.740 ENSMUST00000167607.1
ENSMUST00000115010.2
Ucma

upper zone of growth plate and cartilage matrix associated

chr15_-_85581809 0.738 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr11_+_4873951 0.731 ENSMUST00000038570.2
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr6_-_48841098 0.728 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr11_-_106160708 0.714 ENSMUST00000106875.1
Limd2
LIM domain containing 2
chr7_-_126704816 0.705 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr9_-_106465940 0.701 ENSMUST00000164834.1
Gpr62
G protein-coupled receptor 62
chr16_-_45724600 0.686 ENSMUST00000096057.4
Tagln3
transgelin 3
chr6_+_48841476 0.666 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr6_-_48841373 0.658 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr10_+_127266256 0.642 ENSMUST00000026479.9
Dctn2
dynactin 2
chr6_+_48841633 0.642 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr4_+_109978004 0.625 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr19_+_6497772 0.621 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2

neurexin II

chr8_+_58912257 0.605 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr8_+_3493135 0.603 ENSMUST00000061508.7
Zfp358
zinc finger protein 358
chr11_+_108920800 0.589 ENSMUST00000140821.1
Axin2
axin2
chr7_-_142061021 0.583 ENSMUST00000084418.2
Mob2
MOB kinase activator 2
chr17_+_80127447 0.580 ENSMUST00000039205.4
Galm
galactose mutarotase
chr2_-_152830615 0.578 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr6_-_124911636 0.574 ENSMUST00000032217.1
Lag3
lymphocyte-activation gene 3
chr3_+_66981352 0.563 ENSMUST00000162036.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr16_-_32099697 0.544 ENSMUST00000155966.1
ENSMUST00000096109.4
Pigx

phosphatidylinositol glycan anchor biosynthesis, class X

chr8_+_35587780 0.539 ENSMUST00000037666.5
Mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr3_+_87971129 0.518 ENSMUST00000160694.1
Nes
nestin
chr3_+_87971071 0.514 ENSMUST00000090973.5
Nes
nestin
chr7_-_35647441 0.513 ENSMUST00000118501.1
Pdcd5
programmed cell death 5
chr11_+_101468164 0.510 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr5_+_140419248 0.493 ENSMUST00000100507.3
Eif3b
eukaryotic translation initiation factor 3, subunit B
chr7_+_127746775 0.486 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr6_+_120666388 0.485 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr17_-_56830916 0.485 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chrX_-_152368680 0.484 ENSMUST00000070316.5
Gpr173
G-protein coupled receptor 173
chr2_+_119351222 0.482 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr9_+_21723576 0.479 ENSMUST00000034713.7
Ldlr
low density lipoprotein receptor
chr12_+_109544498 0.476 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr10_-_128211788 0.471 ENSMUST00000061995.8
Spryd4
SPRY domain containing 4
chr17_-_57031468 0.471 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr2_+_174330006 0.470 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chrX_-_7947553 0.458 ENSMUST00000133349.1
Hdac6
histone deacetylase 6
chr17_-_34118476 0.449 ENSMUST00000095347.5
Brd2
bromodomain containing 2
chr7_-_126799163 0.447 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr17_-_57087729 0.437 ENSMUST00000071135.5
Tubb4a
tubulin, beta 4A class IVA
chr5_-_134314637 0.424 ENSMUST00000173504.1
Gtf2i
general transcription factor II I
chr4_-_42661893 0.417 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr7_+_45872772 0.413 ENSMUST00000002855.5
ENSMUST00000107719.1
Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr5_-_137533212 0.407 ENSMUST00000111038.1
ENSMUST00000143495.1
Epo
Gnb2
erythropoietin
guanine nucleotide binding protein (G protein), beta 2
chr7_-_126799134 0.391 ENSMUST00000087566.4
Aldoa
aldolase A, fructose-bisphosphate
chr7_+_28881656 0.391 ENSMUST00000066880.4
Capn12
calpain 12
chr13_-_58402476 0.380 ENSMUST00000175847.1
ENSMUST00000043269.7
ENSMUST00000177060.1
Hnrnpk


heterogeneous nuclear ribonucleoprotein K


chr11_+_77493408 0.376 ENSMUST00000037285.3
ENSMUST00000100812.3
Git1

G protein-coupled receptor kinase-interactor 1

chr5_-_114273702 0.374 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr7_-_35647127 0.373 ENSMUST00000120714.1
Pdcd5
programmed cell death 5
chr11_+_72042455 0.371 ENSMUST00000021164.3
Fam64a
family with sequence similarity 64, member A
chr17_-_46629420 0.361 ENSMUST00000044442.8
Ptk7
PTK7 protein tyrosine kinase 7
chr12_+_73123709 0.360 ENSMUST00000021523.6
Mnat1
menage a trois 1
chr5_+_115279666 0.360 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr7_-_19665005 0.360 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr8_-_111743799 0.355 ENSMUST00000166232.2
Bcar1
breast cancer anti-estrogen resistance 1
chr7_-_122101735 0.348 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
Ndufab1



NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1



chr11_+_70018421 0.347 ENSMUST00000108588.1
Dlg4
discs, large homolog 4 (Drosophila)
chr13_-_34077992 0.346 ENSMUST00000056427.8
Tubb2a
tubulin, beta 2A class IIA
chr1_+_172126750 0.344 ENSMUST00000075895.2
ENSMUST00000111252.3
Pex19

peroxisomal biogenesis factor 19

chr9_+_107975529 0.330 ENSMUST00000035216.4
Uba7
ubiquitin-like modifier activating enzyme 7
chrX_+_36598199 0.330 ENSMUST00000073339.6
Pgrmc1
progesterone receptor membrane component 1
chr5_-_137533170 0.323 ENSMUST00000168746.1
ENSMUST00000170293.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr11_+_98795495 0.318 ENSMUST00000037915.2
Msl1
male-specific lethal 1 homolog (Drosophila)
chr5_-_110387090 0.317 ENSMUST00000056124.6
Fbrsl1
fibrosin-like 1
chr2_-_154569720 0.317 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr8_-_23257043 0.313 ENSMUST00000051094.6
Golga7
golgi autoantigen, golgin subfamily a, 7
chr8_-_23257009 0.311 ENSMUST00000121783.1
Golga7
golgi autoantigen, golgin subfamily a, 7
chr11_-_70669283 0.310 ENSMUST00000129434.1
ENSMUST00000018431.6
Spag7

sperm associated antigen 7

chr8_-_58911627 0.307 ENSMUST00000077447.4
Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr4_-_128962420 0.302 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
Adc


arginine decarboxylase


chr5_-_123524124 0.294 ENSMUST00000111586.1
ENSMUST00000031385.6
ENSMUST00000111587.3
Diablo


diablo homolog (Drosophila)


chr19_-_45742873 0.294 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
Fgf8


fibroblast growth factor 8


chr4_-_49593875 0.292 ENSMUST00000151542.1
Tmem246
transmembrane protein 246
chr4_-_117914968 0.291 ENSMUST00000036156.5
Ipo13
importin 13
chr8_-_120101473 0.288 ENSMUST00000034280.7
Zdhhc7
zinc finger, DHHC domain containing 7
chr10_+_36974536 0.286 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr2_-_170427828 0.283 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr6_-_125165576 0.283 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr12_-_80643799 0.282 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr12_-_108275409 0.280 ENSMUST00000136175.1
Ccdc85c
coiled-coil domain containing 85C
chr12_-_108835845 0.279 ENSMUST00000021693.3
Slc25a29
solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29
chr11_+_77763246 0.278 ENSMUST00000108375.2
Myo18a
myosin XVIIIA
chr5_-_134614953 0.276 ENSMUST00000036362.6
ENSMUST00000077636.4
Lat2

linker for activation of T cells family, member 2

chr7_-_30195046 0.265 ENSMUST00000001845.5
Capns1
calpain, small subunit 1
chr8_+_105690906 0.263 ENSMUST00000062574.6
Rltpr
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr7_+_97332311 0.263 ENSMUST00000054107.5
Kctd21
potassium channel tetramerisation domain containing 21
chr2_+_26583858 0.261 ENSMUST00000100290.5
ENSMUST00000102907.5
Egfl7

EGF-like domain 7

chr10_+_127078886 0.255 ENSMUST00000039259.6
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr8_+_3631109 0.253 ENSMUST00000004745.8
Stxbp2
syntaxin binding protein 2
chr7_+_3289012 0.240 ENSMUST00000164553.1
Myadm
myeloid-associated differentiation marker
chr5_-_110839757 0.233 ENSMUST00000056937.5
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr2_+_105668935 0.211 ENSMUST00000142772.1
Pax6
paired box gene 6
chr16_+_72663143 0.197 ENSMUST00000023600.7
Robo1
roundabout homolog 1 (Drosophila)
chr7_-_30193098 0.195 ENSMUST00000108196.1
Capns1
calpain, small subunit 1
chr16_-_34573526 0.195 ENSMUST00000114961.1
Kalrn
kalirin, RhoGEF kinase
chr6_+_113604749 0.192 ENSMUST00000035725.5
Brk1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr10_+_36974558 0.190 ENSMUST00000105510.1
Hdac2
histone deacetylase 2
chr4_-_15945359 0.185 ENSMUST00000029877.8
Decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr7_-_133122615 0.185 ENSMUST00000167218.1
Ctbp2
C-terminal binding protein 2
chr17_-_31512253 0.183 ENSMUST00000166626.1
Wdr4
WD repeat domain 4
chr5_-_134314378 0.181 ENSMUST00000174867.1
Gtf2i
general transcription factor II I
chr5_+_142629537 0.178 ENSMUST00000036872.9
ENSMUST00000110778.1
Wipi2

WD repeat domain, phosphoinositide interacting 2

chr19_+_8735808 0.173 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr7_-_45016224 0.161 ENSMUST00000085383.2
Scaf1
SR-related CTD-associated factor 1
chr11_-_84819450 0.151 ENSMUST00000018549.7
Mrm1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr3_-_90509450 0.151 ENSMUST00000107343.1
ENSMUST00000001043.7
ENSMUST00000107344.1
ENSMUST00000076639.4
ENSMUST00000107346.1
ENSMUST00000146740.1
ENSMUST00000107342.1
ENSMUST00000049937.6
Chtop







chromatin target of PRMT1







chr1_+_156035705 0.144 ENSMUST00000111754.2
ENSMUST00000133152.1
Tor1aip2

torsin A interacting protein 2

chr8_-_40634750 0.143 ENSMUST00000173957.1
Mtmr7
myotubularin related protein 7
chr5_+_37338455 0.136 ENSMUST00000056365.8
Evc2
Ellis van Creveld syndrome 2
chr1_-_173367638 0.129 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr7_+_144915124 0.122 ENSMUST00000033388.5
ENSMUST00000105895.1
Oraov1

oral cancer overexpressed 1

chr10_+_80016901 0.117 ENSMUST00000105373.1
Hmha1
histocompatibility (minor) HA-1
chr6_-_51469836 0.117 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr5_-_110839575 0.111 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr10_-_81060134 0.099 ENSMUST00000005067.5
Sgta
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr9_-_121839460 0.095 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr3_-_89322883 0.093 ENSMUST00000029673.5
Efna3
ephrin A3
chr6_-_51469869 0.093 ENSMUST00000114459.1
ENSMUST00000069949.6
Hnrnpa2b1

heterogeneous nuclear ribonucleoprotein A2/B1

chr14_+_64588112 0.091 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr16_+_32099781 0.091 ENSMUST00000115168.2
Cep19
centrosomal protein 19
chr12_+_109545390 0.089 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr17_+_6978860 0.087 ENSMUST00000089119.5
ENSMUST00000179728.1
Rnaset2b

ribonuclease T2B

chr9_-_108083330 0.086 ENSMUST00000159372.1
ENSMUST00000160249.1
Rnf123

ring finger protein 123

chr8_-_109251698 0.081 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr12_+_72085847 0.077 ENSMUST00000117449.1
ENSMUST00000057257.8
Jkamp

JNK1/MAPK8-associated membrane protein

chr2_-_3512746 0.074 ENSMUST00000027961.5
ENSMUST00000056700.7
Hspa14
Hspa14
heat shock protein 14
heat shock protein 14
chr17_+_29679247 0.072 ENSMUST00000129864.1
Cmtr1
cap methyltransferase 1
chr7_-_19715395 0.066 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr17_-_34122311 0.063 ENSMUST00000025193.6
Brd2
bromodomain containing 2
chr11_+_69098937 0.049 ENSMUST00000021271.7
Per1
period circadian clock 1
chr5_-_122989086 0.045 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr11_+_103649498 0.044 ENSMUST00000057870.2
Rprml
reprimo-like
chr12_+_53248677 0.032 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr2_+_90677208 0.019 ENSMUST00000057481.6
Nup160
nucleoporin 160
chr1_-_74284636 0.018 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr13_-_35027077 0.016 ENSMUST00000170538.1
ENSMUST00000163280.1
Eci2

enoyl-Coenzyme A delta isomerase 2

chr2_-_152831112 0.014 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr8_+_25754492 0.013 ENSMUST00000167899.1
Gm17484
predicted gene, 17484
chr7_-_114636299 0.012 ENSMUST00000032906.4
ENSMUST00000032907.7
Calca

calcitonin/calcitonin-related polypeptide, alpha

chr1_-_93801840 0.010 ENSMUST00000112890.2
ENSMUST00000027503.7
Dtymk

deoxythymidylate kinase

chr1_+_191718389 0.010 ENSMUST00000110856.1
ENSMUST00000130876.1
Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr5_-_122989260 0.008 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr8_-_40634776 0.008 ENSMUST00000048898.10
ENSMUST00000174205.1
Mtmr7

myotubularin related protein 7

chr16_+_29209695 0.005 ENSMUST00000089824.4
Hrasls
HRAS-like suppressor
chr7_+_35334175 0.004 ENSMUST00000032705.6
ENSMUST00000085556.3
Rhpn2

rhophilin, Rho GTPase binding protein 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.7 6.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.6 2.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.5 3.7 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.5 3.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.4 2.1 GO:0015671 oxygen transport(GO:0015671)
0.4 5.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 1.8 GO:0032796 uropod organization(GO:0032796)
0.2 0.7 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.2 0.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) retinal rod cell differentiation(GO:0060221)
0.2 0.6 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 1.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 0.5 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
0.2 0.5 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.2 0.8 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.6 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.6 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.4 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.3 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 1.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.5 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.4 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.7 GO:0015074 DNA integration(GO:0015074)
0.1 0.9 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040) negative regulation of protein folding(GO:1903333)
0.1 0.3 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.1 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.8 GO:0007220 Notch receptor processing(GO:0007220)
0.1 3.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 8.3 GO:0007498 mesoderm development(GO:0007498)
0.1 0.5 GO:0001842 neural fold formation(GO:0001842)
0.1 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.3 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.4 GO:0001771 immunological synapse formation(GO:0001771)
0.1 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.4 GO:0035729 response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.5 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.4 GO:0007512 adult heart development(GO:0007512)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.3 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.6 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0 0.6 GO:0032402 melanosome transport(GO:0032402)
0.0 0.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.3 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.4 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.5 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0033193 Lsd1/2 complex(GO:0033193)
0.4 3.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 2.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.3 2.1 GO:0005833 hemoglobin complex(GO:0005833)
0.2 3.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.5 GO:0090537 CERF complex(GO:0090537)
0.1 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.6 GO:0044306 neuron projection terminus(GO:0044306)
0.1 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 1.6 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0009986 cell surface(GO:0009986)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.5 GO:0019841 retinol binding(GO:0019841)
0.5 2.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.3 2.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.3 0.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 3.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 1.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 2.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 2.8 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.7 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 11.7 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)