Motif ID: Grhl1

Z-value: 0.348


Transcription factors associated with Grhl1:

Gene SymbolEntrez IDGene Name
Grhl1 ENSMUSG00000020656.9 Grhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Grhl1mm10_v2_chr12_+_24572276_245723080.174.1e-01Click!


Activity profile for motif Grhl1.

activity profile for motif Grhl1


Sorted Z-values histogram for motif Grhl1

Sorted Z-values for motif Grhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Grhl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_87635974 0.670 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule
chr3_-_87263518 0.588 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr16_-_26989974 0.543 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr14_-_57133268 0.527 ENSMUST00000160703.1
 Gjb6
gap junction protein, beta 6
chr3_-_87263703 0.525 ENSMUST00000146512.1
 Fcrls
Fc receptor-like S, scavenger receptor
chr14_+_75136326 0.514 ENSMUST00000145303.1
 Lcp1
lymphocyte cytosolic protein 1
chr8_+_80494032 0.502 ENSMUST00000063359.6
 Gypa
glycophorin A
chr5_-_86676346 0.477 ENSMUST00000038448.6
 Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr18_+_56432116 0.435 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr10_-_79533750 0.333 ENSMUST00000166804.1
ENSMUST00000063879.5
 Ppap2c

phosphatidic acid phosphatase type 2C

chr19_-_18631754 0.294 ENSMUST00000025631.6
 Ostf1
osteoclast stimulating factor 1
chr14_+_63943666 0.269 ENSMUST00000079652.5
 Sox7
SRY-box containing gene 7
chr9_+_15239045 0.194 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr2_+_149830788 0.182 ENSMUST00000109935.1
 Syndig1
synapse differentiation inducing 1
chr7_+_101321703 0.178 ENSMUST00000174291.1
ENSMUST00000167888.2
ENSMUST00000172662.1
ENSMUST00000173270.1
ENSMUST00000174083.1
 Stard10




START domain containing 10




chr4_+_109676568 0.178 ENSMUST00000102724.4
 Faf1
Fas-associated factor 1
chr2_+_149830840 0.175 ENSMUST00000109934.1
ENSMUST00000140870.1
 Syndig1

synapse differentiation inducing 1

chr1_+_135818593 0.165 ENSMUST00000038760.8
 Lad1
ladinin
chr12_+_76417598 0.143 ENSMUST00000063977.7
 Ppp1r36
protein phosphatase 1, regulatory subunit 36
chr7_+_65693417 0.136 ENSMUST00000032726.7
ENSMUST00000107495.3
 Tm2d3

TM2 domain containing 3

chr4_+_155086577 0.130 ENSMUST00000030915.4
ENSMUST00000155775.1
ENSMUST00000127457.1
 Morn1


MORN repeat containing 1


chr10_-_128565827 0.127 ENSMUST00000131728.1
ENSMUST00000026425.6
 Pa2g4

proliferation-associated 2G4

chr2_-_25546872 0.124 ENSMUST00000114234.1
ENSMUST00000028311.6
 Traf2

TNF receptor-associated factor 2

chr2_+_149830894 0.120 ENSMUST00000137280.1
ENSMUST00000149705.1
 Syndig1

synapse differentiation inducing 1

chr7_-_102065044 0.119 ENSMUST00000130074.1
ENSMUST00000131104.1
ENSMUST00000096639.5
 Rnf121


ring finger protein 121


chr10_+_128747850 0.115 ENSMUST00000163377.2
 Wibg
within bgcn homolog (Drosophila)
chr12_+_90738201 0.106 ENSMUST00000181874.1
 Gm26512
predicted gene, 26512
chr8_-_71381907 0.102 ENSMUST00000002466.8
 Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr4_-_155086271 0.097 ENSMUST00000030914.3
 Rer1
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
chrX_+_100730178 0.096 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr7_+_12927410 0.096 ENSMUST00000045870.4
 2310014L17Rik
RIKEN cDNA 2310014L17 gene
chr13_+_8885501 0.095 ENSMUST00000169314.2
 Idi1
isopentenyl-diphosphate delta isomerase
chr9_-_107541816 0.079 ENSMUST00000041459.3
 Cyb561d2
cytochrome b-561 domain containing 2
chr17_-_56005566 0.079 ENSMUST00000043785.6
 Stap2
signal transducing adaptor family member 2
chr17_+_43389436 0.078 ENSMUST00000113599.1
 Gpr116
G protein-coupled receptor 116
chr5_+_130029277 0.076 ENSMUST00000026608.7
 Crcp
calcitonin gene-related peptide-receptor component protein
chr8_+_123477859 0.074 ENSMUST00000001520.7
 Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr17_-_34628005 0.072 ENSMUST00000166040.2
 Ppt2
palmitoyl-protein thioesterase 2
chr2_-_30967859 0.068 ENSMUST00000028200.8
 Tor1a
torsin family 1, member A (torsin A)
chr9_+_108508005 0.062 ENSMUST00000006838.8
ENSMUST00000134939.1
 Qars

glutaminyl-tRNA synthetase

chr12_-_54656496 0.044 ENSMUST00000056228.6
 Sptssa
serine palmitoyltransferase, small subunit A
chr4_+_108834601 0.044 ENSMUST00000030296.8
 Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr8_-_69996326 0.040 ENSMUST00000177851.1
ENSMUST00000065169.4
 Gatad2a

GATA zinc finger domain containing 2A

chr9_-_7872983 0.040 ENSMUST00000115672.1
 Birc3
baculoviral IAP repeat-containing 3
chr17_+_36837123 0.040 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
 Trim26





tripartite motif-containing 26





chr19_+_5568002 0.039 ENSMUST00000096318.3
 Ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr2_-_30205794 0.038 ENSMUST00000113663.2
ENSMUST00000044038.3
 Ccbl1

cysteine conjugate-beta lyase 1

chr6_-_113377376 0.035 ENSMUST00000043333.2
 Tada3
transcriptional adaptor 3
chr17_-_34628380 0.027 ENSMUST00000167097.2
 Ppt2
palmitoyl-protein thioesterase 2
chr8_-_95853501 0.022 ENSMUST00000040481.3
 Slc38a7
solute carrier family 38, member 7
chr17_+_29268788 0.022 ENSMUST00000064709.5
ENSMUST00000120346.1
 BC004004

cDNA sequence BC004004

chr6_-_113377510 0.013 ENSMUST00000099118.2
 Tada3
transcriptional adaptor 3
chr7_-_45333754 0.011 ENSMUST00000042194.8
 Trpm4
transient receptor potential cation channel, subfamily M, member 4
chr9_-_44268156 0.010 ENSMUST00000169651.1
 Nlrx1
NLR family member X1
chr2_-_30205772 0.007 ENSMUST00000113662.1
 Ccbl1
cysteine conjugate-beta lyase 1
chr7_-_30552255 0.007 ENSMUST00000108165.1
ENSMUST00000153594.1
 BC053749

cDNA sequence BC053749


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.5 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.5 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.0 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891) podosome(GO:0002102)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.0 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)