Motif ID: Hand1
Z-value: 1.509
Transcription factors associated with Hand1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hand1 | ENSMUSG00000037335.7 | Hand1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.1 | GO:0071873 | response to norepinephrine(GO:0071873) |
| 2.0 | 5.9 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
| 1.3 | 3.9 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 1.1 | 3.4 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 1.0 | 3.1 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
| 1.0 | 4.0 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 1.0 | 12.7 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 1.0 | 3.8 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 1.0 | 4.8 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
| 0.9 | 2.8 | GO:0071544 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544) |
| 0.8 | 2.5 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
| 0.8 | 5.0 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
| 0.8 | 2.4 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
| 0.7 | 0.7 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 0.7 | 3.4 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.7 | 2.0 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.6 | 2.4 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.6 | 1.7 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.5 | 2.7 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 0.5 | 5.5 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.5 | 3.3 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
| 0.5 | 1.0 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.5 | 7.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.4 | 1.8 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
| 0.4 | 1.3 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.4 | 4.1 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.4 | 1.2 | GO:0031117 | serotonin receptor signaling pathway(GO:0007210) positive regulation of microtubule depolymerization(GO:0031117) |
| 0.4 | 0.8 | GO:0002578 | negative regulation of antigen processing and presentation(GO:0002578) |
| 0.4 | 1.5 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.4 | 1.9 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.4 | 2.6 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.4 | 3.7 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.4 | 1.1 | GO:0070543 | response to linoleic acid(GO:0070543) |
| 0.4 | 1.5 | GO:0032439 | endosome localization(GO:0032439) |
| 0.4 | 1.8 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
| 0.4 | 3.2 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.3 | 1.0 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.3 | 2.3 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.3 | 2.6 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.3 | 0.6 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.3 | 0.9 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.3 | 1.2 | GO:0002606 | dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606) |
| 0.3 | 7.4 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.3 | 1.2 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
| 0.3 | 2.1 | GO:0071635 | negative regulation of transforming growth factor beta production(GO:0071635) |
| 0.3 | 8.5 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
| 0.3 | 1.1 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.3 | 1.7 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glycolytic process through glucose-1-phosphate(GO:0061622) glucose catabolic process to pyruvate(GO:0061718) |
| 0.3 | 4.6 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.3 | 1.0 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 0.3 | 1.0 | GO:0034727 | lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805) |
| 0.3 | 1.5 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
| 0.2 | 1.2 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 1.5 | GO:0097369 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.2 | 3.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.2 | 1.2 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.2 | 2.4 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.2 | 0.7 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 1.1 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 0.2 | 3.3 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.2 | 2.0 | GO:0035898 | parathyroid hormone secretion(GO:0035898) |
| 0.2 | 1.7 | GO:0043312 | neutrophil degranulation(GO:0043312) |
| 0.2 | 0.7 | GO:0006788 | heme oxidation(GO:0006788) |
| 0.2 | 1.0 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.2 | 1.5 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.2 | 2.7 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.2 | 2.5 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.2 | 1.2 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.2 | 1.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.2 | 0.9 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 1.8 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 3.2 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.8 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
| 0.1 | 0.7 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 2.0 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 0.4 | GO:0009223 | pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
| 0.1 | 0.8 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.1 | 3.2 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.1 | 0.8 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 5.9 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
| 0.1 | 0.9 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 0.5 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.1 | 3.7 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.1 | 0.6 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.1 | 0.8 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.1 | 3.5 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.1 | 0.2 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.1 | 1.4 | GO:0030204 | chondroitin sulfate metabolic process(GO:0030204) |
| 0.1 | 0.7 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.1 | 1.4 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.1 | 2.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.1 | 2.4 | GO:0009299 | mRNA transcription(GO:0009299) |
| 0.1 | 0.2 | GO:0044351 | regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) macropinocytosis(GO:0044351) |
| 0.1 | 0.1 | GO:0071436 | sodium ion export(GO:0071436) |
| 0.1 | 0.6 | GO:0001845 | phagolysosome assembly(GO:0001845) |
| 0.1 | 0.2 | GO:0060023 | soft palate development(GO:0060023) |
| 0.1 | 1.3 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
| 0.1 | 0.3 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.7 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.1 | 0.6 | GO:0042989 | sequestering of actin monomers(GO:0042989) actin filament severing(GO:0051014) |
| 0.1 | 1.1 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
| 0.0 | 5.4 | GO:0007613 | memory(GO:0007613) |
| 0.0 | 0.2 | GO:0045896 | regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) |
| 0.0 | 0.3 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.0 | 1.0 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
| 0.0 | 0.5 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.0 | 0.6 | GO:0097576 | autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576) |
| 0.0 | 0.8 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.0 | 4.7 | GO:0006906 | vesicle fusion(GO:0006906) |
| 0.0 | 2.4 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 0.0 | 0.1 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) |
| 0.0 | 1.1 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 1.6 | GO:0006998 | nuclear envelope organization(GO:0006998) |
| 0.0 | 0.7 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.5 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.5 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.0 | 0.4 | GO:0051220 | cytoplasmic sequestering of protein(GO:0051220) |
| 0.0 | 0.7 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 4.1 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 0.4 | GO:0032402 | melanosome transport(GO:0032402) pigment granule transport(GO:0051904) |
| 0.0 | 0.2 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.0 | 0.2 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
| 0.0 | 0.5 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.0 | 0.5 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.0 | 0.5 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.0 | 0.6 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.4 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
| 0.0 | 0.3 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.0 | 0.8 | GO:0015908 | fatty acid transport(GO:0015908) |
| 0.0 | 0.1 | GO:0003094 | glomerular filtration(GO:0003094) renal filtration(GO:0097205) |
| 0.0 | 0.3 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.0 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.0 | 0.5 | GO:0043113 | receptor clustering(GO:0043113) |
| 0.0 | 7.0 | GO:0006397 | mRNA processing(GO:0006397) |
| 0.0 | 0.1 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.0 | 1.0 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.3 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.0 | 1.2 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.0 | 0.8 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.0 | 1.0 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.0 | 2.2 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 2.5 | GO:0016042 | lipid catabolic process(GO:0016042) |
| 0.0 | 0.4 | GO:0006829 | zinc II ion transport(GO:0006829) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 10.0 | GO:0044308 | axonal spine(GO:0044308) |
| 1.7 | 5.0 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 1.3 | 3.8 | GO:0044299 | C-fiber(GO:0044299) |
| 1.1 | 3.3 | GO:0043512 | inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512) |
| 1.1 | 6.3 | GO:1990635 | proximal dendrite(GO:1990635) |
| 1.0 | 5.1 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.8 | 2.4 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.5 | 3.8 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.4 | 1.8 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.4 | 1.3 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.4 | 1.7 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.4 | 2.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.3 | 1.5 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.3 | 3.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.2 | 1.2 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.2 | 4.1 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.2 | 0.8 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.2 | 1.1 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.2 | 1.5 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.2 | 2.7 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.2 | 0.9 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.2 | 8.4 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.2 | 5.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.2 | 0.8 | GO:1990357 | terminal web(GO:1990357) |
| 0.2 | 1.7 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.1 | 1.0 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 1.5 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.1 | 0.6 | GO:0002139 | stereocilia coupling link(GO:0002139) |
| 0.1 | 4.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 1.2 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 0.3 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 0.3 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 0.7 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.1 | 1.2 | GO:0043203 | axon hillock(GO:0043203) |
| 0.1 | 3.6 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.1 | 0.3 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.1 | 7.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 7.0 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 0.7 | GO:0031091 | platelet alpha granule(GO:0031091) |
| 0.1 | 4.7 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.1 | 3.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 5.6 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 1.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 3.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 2.1 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.1 | 4.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 0.9 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 0.2 | GO:0061702 | inflammasome complex(GO:0061702) |
| 0.1 | 0.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 2.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.2 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.7 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.0 | 0.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 0.4 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 2.4 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 1.7 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 5.3 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 3.7 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 4.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.3 | GO:0089701 | U2AF(GO:0089701) |
| 0.0 | 1.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.4 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.0 | 0.1 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.0 | 2.1 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 3.5 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 2.4 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 1.0 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 1.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.4 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 1.9 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 5.4 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 3.9 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.8 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 1.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.3 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.7 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 2.0 | GO:0030141 | secretory granule(GO:0030141) |
| 0.0 | 0.3 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 1.2 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.5 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.4 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) |
| 0.0 | 1.5 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 0.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.9 | GO:0060076 | excitatory synapse(GO:0060076) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 8.1 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 1.3 | 5.1 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 1.2 | 5.0 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
| 1.2 | 8.5 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 1.0 | 5.9 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 1.0 | 3.8 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.9 | 2.8 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.9 | 2.6 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.8 | 5.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.8 | 3.4 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
| 0.8 | 2.4 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.8 | 3.8 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.6 | 2.4 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.6 | 2.3 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.5 | 3.2 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.5 | 2.1 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.5 | 3.4 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.5 | 2.8 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 0.5 | 3.3 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.4 | 1.7 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.4 | 1.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.4 | 1.8 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.4 | 1.8 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.3 | 1.4 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.3 | 2.7 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.3 | 5.5 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.3 | 3.8 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.3 | 0.9 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.3 | 1.2 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589) |
| 0.3 | 5.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.3 | 1.8 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.3 | 1.3 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
| 0.2 | 1.5 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.2 | 1.4 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.2 | 4.1 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.2 | 4.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.2 | 1.3 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.2 | 2.3 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.2 | 3.9 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.2 | 0.6 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.2 | 3.1 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.2 | 4.1 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.2 | 3.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.2 | 1.1 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.2 | 1.5 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.2 | 0.7 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.2 | 2.5 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.2 | 0.5 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.2 | 1.2 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.2 | 2.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.7 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.1 | 1.6 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
| 0.1 | 1.1 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.1 | 1.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 4.0 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 0.9 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 7.5 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.1 | 0.9 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.1 | 0.3 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.1 | 5.9 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.1 | 2.1 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
| 0.1 | 0.8 | GO:0047499 | lysophospholipase activity(GO:0004622) calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.1 | 0.8 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.1 | 1.5 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.1 | 1.5 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.1 | 1.0 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.1 | 2.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.8 | GO:0034943 | acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409) |
| 0.1 | 1.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 0.8 | GO:0045309 | protein phosphorylated amino acid binding(GO:0045309) |
| 0.1 | 0.8 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.1 | 0.6 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.1 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 1.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.7 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.1 | 1.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 0.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 1.2 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 3.2 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.4 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.0 | 0.2 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) |
| 0.0 | 0.5 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.2 | GO:0080084 | RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084) |
| 0.0 | 1.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 3.8 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.0 | 2.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.1 | GO:0008430 | selenium binding(GO:0008430) |
| 0.0 | 4.9 | GO:0001948 | glycoprotein binding(GO:0001948) |
| 0.0 | 0.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 2.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 1.1 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 1.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.3 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.0 | 3.4 | GO:0005539 | glycosaminoglycan binding(GO:0005539) |
| 0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.0 | 5.3 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.7 | GO:0051537 | ferrous iron binding(GO:0008198) 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.5 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.5 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.8 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.2 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.1 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.0 | 0.3 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.8 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
| 0.0 | 0.1 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
| 0.0 | 2.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.1 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 2.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 1.8 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.0 | 0.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.3 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.7 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.7 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.1 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 1.0 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.7 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
