Motif ID: Hdx

Z-value: 5.537


Transcription factors associated with Hdx:

Gene SymbolEntrez IDGene Name
Hdx ENSMUSG00000034551.6 Hdx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hdxmm10_v2_chrX_-_111697069_111697127-0.106.3e-01Click!


Activity profile for motif Hdx.

activity profile for motif Hdx


Sorted Z-values histogram for motif Hdx

Sorted Z-values for motif Hdx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hdx

PNG image of the network

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Top targets:


Showing 1 to 20 of 94 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3017408 111.946 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3015654 100.046 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr9_+_3005125 91.001 ENSMUST00000179881.1
 Gm11168
predicted gene 11168
chr9_+_3023547 87.444 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3034599 79.470 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr9_+_3000922 77.015 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3027439 71.785 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3025417 68.035 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr14_-_19418930 63.355 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3018753 57.111 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr9_+_3004457 52.713 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3036877 48.231 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr9_+_3037111 44.811 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3013140 40.795 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr2_-_98667264 29.502 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr6_-_23248264 14.703 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr13_+_24327415 7.897 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr15_+_10177623 4.619 ENSMUST00000124470.1
 Prlr
prolactin receptor
chr16_-_26989974 4.297 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chrX_-_21089229 4.223 ENSMUST00000040667.6
 Zfp300
zinc finger protein 300

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 676.4 GO:0008150 biological_process(GO:0008150)
2.5 14.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.6 7.9 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.9 4.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) prolactin signaling pathway(GO:0038161)
0.1 4.3 GO:0006270 DNA replication initiation(GO:0006270)
1.3 3.8 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 3.8 GO:0021884 forebrain neuron development(GO:0021884)
0.1 3.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
1.1 3.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 2.2 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 1.9 GO:0097352 autophagosome maturation(GO:0097352)
0.3 1.8 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 1.8 GO:0030432 peristalsis(GO:0030432)
0.1 1.8 GO:0034063 stress granule assembly(GO:0034063)
0.3 1.5 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 1.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.4 1.1 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) musculoskeletal movement, spinal reflex action(GO:0050883) acetylcholine secretion(GO:0061526)
0.2 1.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 1.1 GO:0006956 complement activation(GO:0006956)
0.1 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 733.7 GO:0005575 cellular_component(GO:0005575)
0.6 3.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 2.9 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.1 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 695.4 GO:0003674 molecular_function(GO:0003674)
0.1 12.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
2.6 7.9 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 4.6 GO:0017046 peptide hormone binding(GO:0017046)
0.9 3.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 2.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 2.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.9 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.3 1.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.4 1.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 1.3 GO:0001851 complement component C3b binding(GO:0001851)
0.1 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.1 GO:0070330 aromatase activity(GO:0070330)
0.2 1.1 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.6 GO:0050501 hyaluronan synthase activity(GO:0050501)