Motif ID: Hes5_Hes7

Z-value: 1.421

Transcription factors associated with Hes5_Hes7:

Gene SymbolEntrez IDGene Name
Hes5 ENSMUSG00000048001.7 Hes5
Hes7 ENSMUSG00000023781.2 Hes7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hes5mm10_v2_chr4_+_154960915_1549609300.572.4e-03Click!
Hes7mm10_v2_chr11_+_69120404_69120404-0.404.3e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Hes5_Hes7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_12026732 25.317 ENSMUST00000143915.1
Grb10
growth factor receptor bound protein 10
chr11_-_12026237 24.822 ENSMUST00000150972.1
Grb10
growth factor receptor bound protein 10
chr10_-_87493651 8.020 ENSMUST00000020243.7
Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr12_-_56536895 6.793 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr12_+_109459843 6.006 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr6_+_4755327 5.232 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr2_+_163203072 5.162 ENSMUST00000109428.2
Tox2
TOX high mobility group box family member 2
chr5_+_128601106 4.711 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chr9_-_36726374 4.208 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr5_+_28165690 4.160 ENSMUST00000036177.7
En2
engrailed 2
chr2_-_92370999 3.744 ENSMUST00000176810.1
ENSMUST00000090582.4
Gyltl1b

glycosyltransferase-like 1B

chr8_-_87804411 3.411 ENSMUST00000165770.2
Zfp423
zinc finger protein 423
chr13_+_108316332 3.273 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr13_+_108316395 3.243 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr8_+_119446719 3.097 ENSMUST00000098363.3
Necab2
N-terminal EF-hand calcium binding protein 2
chr13_+_51846673 3.026 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr9_+_64121501 2.769 ENSMUST00000118215.1
Lctl
lactase-like
chr2_-_92371039 2.632 ENSMUST00000068586.6
Gyltl1b
glycosyltransferase-like 1B
chr2_-_92370968 2.546 ENSMUST00000176774.1
Gyltl1b
glycosyltransferase-like 1B
chr4_+_137913471 2.525 ENSMUST00000151110.1
Ece1
endothelin converting enzyme 1
chr4_-_132757162 2.463 ENSMUST00000030709.8
Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
chr12_+_109549157 2.423 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3

maternally expressed 3

chr10_+_79682169 2.329 ENSMUST00000020550.5
Cdc34
cell division cycle 34
chr18_-_46280820 2.172 ENSMUST00000025354.3
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr17_-_24960620 1.979 ENSMUST00000024981.7
Hn1l
hematological and neurological expressed 1-like
chr10_+_79682304 1.978 ENSMUST00000166603.1
Cdc34
cell division cycle 34
chr1_+_131962941 1.890 ENSMUST00000177943.1
Slc45a3
solute carrier family 45, member 3
chr2_+_73271925 1.850 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr1_+_72824482 1.743 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr3_-_95855753 1.727 ENSMUST00000161476.1
Prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr7_-_99626936 1.642 ENSMUST00000178124.1
Gm4980
predicted gene 4980
chr4_+_11191354 1.596 ENSMUST00000170901.1
Ccne2
cyclin E2
chr3_-_95855860 1.528 ENSMUST00000015892.7
Prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr17_+_35861318 1.511 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr13_+_35741313 1.450 ENSMUST00000163595.2
Cdyl
chromodomain protein, Y chromosome-like
chr8_+_60632818 1.415 ENSMUST00000161421.1
Mfap3l
microfibrillar-associated protein 3-like
chr11_+_59306920 1.403 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr8_+_60632856 1.390 ENSMUST00000160719.1
Mfap3l
microfibrillar-associated protein 3-like
chr7_-_65370908 1.345 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr11_-_59787636 1.321 ENSMUST00000125307.1
Pld6
phospholipase D family, member 6
chr11_-_50325599 1.311 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr14_+_59201209 1.223 ENSMUST00000173547.1
ENSMUST00000043227.6
ENSMUST00000022551.7
Rcbtb1


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1


chr11_+_120491840 1.216 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr14_+_31019183 1.200 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr7_-_65371210 1.193 ENSMUST00000102592.3
Tjp1
tight junction protein 1
chr14_+_31019125 1.111 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr3_+_104638658 1.058 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr6_-_57692007 1.014 ENSMUST00000053386.5
ENSMUST00000185014.1
Pyurf
PYURF
Pigy upstream reading frame
protein preY, mitochondrial precursor
chr14_+_59201418 0.996 ENSMUST00000140136.2
ENSMUST00000142326.1
Rcbtb1

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

chr15_+_39076885 0.939 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr6_+_91157373 0.857 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr4_-_133756769 0.811 ENSMUST00000008024.6
Arid1a
AT rich interactive domain 1A (SWI-like)
chr2_+_91526756 0.792 ENSMUST00000111338.3
Ckap5
cytoskeleton associated protein 5
chr3_-_101604580 0.708 ENSMUST00000036493.6
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr4_+_123904832 0.686 ENSMUST00000030400.7
Mycbp
c-myc binding protein
chr11_-_86807624 0.647 ENSMUST00000018569.7
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr16_-_33967032 0.635 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chr4_+_154869585 0.602 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
Mmel1


membrane metallo-endopeptidase-like 1


chr15_+_32244801 0.593 ENSMUST00000067458.6
Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr3_-_95882193 0.585 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr9_+_107587711 0.577 ENSMUST00000010192.5
Ifrd2
interferon-related developmental regulator 2
chr1_-_193035651 0.564 ENSMUST00000016344.7
Syt14
synaptotagmin XIV
chr1_-_161876656 0.549 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr17_-_25273861 0.541 ENSMUST00000172868.1
ENSMUST00000172618.1
Ube2i

ubiquitin-conjugating enzyme E2I

chr8_+_106603351 0.541 ENSMUST00000000312.5
ENSMUST00000167688.1
Cdh1

cadherin 1

chr11_+_67025144 0.538 ENSMUST00000079077.5
ENSMUST00000061786.5
Tmem220

transmembrane protein 220

chr2_+_156065738 0.528 ENSMUST00000137966.1
Spag4
sperm associated antigen 4
chr2_+_6322621 0.525 ENSMUST00000114937.1
Usp6nl
USP6 N-terminal like
chr10_-_62651194 0.512 ENSMUST00000020270.4
Ddx50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr14_+_31019159 0.510 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr3_-_95882031 0.463 ENSMUST00000161994.1
Gm129
predicted gene 129
chr4_+_117251951 0.460 ENSMUST00000062824.5
Tmem53
transmembrane protein 53
chr11_+_97315716 0.460 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr4_+_99929414 0.448 ENSMUST00000058351.9
Pgm2
phosphoglucomutase 2
chr10_+_36974536 0.444 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr6_+_35177610 0.444 ENSMUST00000170234.1
Nup205
nucleoporin 205
chr6_-_47813512 0.426 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr8_+_124722139 0.410 ENSMUST00000034463.3
Arv1
ARV1 homolog (yeast)
chr2_+_49451486 0.406 ENSMUST00000092123.4
Epc2
enhancer of polycomb homolog 2 (Drosophila)
chr8_-_124721956 0.400 ENSMUST00000117624.1
ENSMUST00000041614.8
ENSMUST00000118134.1
Ttc13


tetratricopeptide repeat domain 13


chr11_-_78165521 0.384 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr5_+_147860615 0.380 ENSMUST00000031654.6
Pomp
proteasome maturation protein
chr3_-_95882232 0.377 ENSMUST00000161866.1
Gm129
predicted gene 129
chr3_-_90052463 0.339 ENSMUST00000029553.9
ENSMUST00000064639.8
ENSMUST00000090908.6
Ubap2l


ubiquitin associated protein 2-like


chr12_+_72761211 0.333 ENSMUST00000021514.8
Ppm1a
protein phosphatase 1A, magnesium dependent, alpha isoform
chr4_+_123904907 0.323 ENSMUST00000106202.3
Mycbp
c-myc binding protein
chr11_+_4637734 0.315 ENSMUST00000109930.2
ENSMUST00000070257.7
Ascc2

activating signal cointegrator 1 complex subunit 2

chr3_+_90052814 0.290 ENSMUST00000160640.1
ENSMUST00000029552.6
ENSMUST00000162114.1
ENSMUST00000068798.6
4933434E20Rik



RIKEN cDNA 4933434E20 gene



chr4_-_123904826 0.289 ENSMUST00000181292.1
Gm26606
predicted gene, 26606
chr4_-_43562397 0.283 ENSMUST00000030187.7
Tln1
talin 1
chr17_-_25274299 0.280 ENSMUST00000172587.1
ENSMUST00000049911.9
ENSMUST00000173713.1
Ube2i


ubiquitin-conjugating enzyme E2I


chr12_+_69372112 0.260 ENSMUST00000050063.7
Arf6
ADP-ribosylation factor 6
chr4_+_117252010 0.255 ENSMUST00000125943.1
ENSMUST00000106434.1
Tmem53

transmembrane protein 53

chr12_+_77239036 0.237 ENSMUST00000062804.7
Fut8
fucosyltransferase 8
chrX_+_8271133 0.172 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr4_+_118428078 0.163 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
Elovl1


elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1


chr1_+_193173469 0.142 ENSMUST00000161235.1
ENSMUST00000110831.2
ENSMUST00000178744.1
A130010J15Rik


RIKEN cDNA A130010J15 gene


chr15_+_102073773 0.131 ENSMUST00000169681.1
Eif4b
eukaryotic translation initiation factor 4B
chr6_-_145076106 0.107 ENSMUST00000111742.1
ENSMUST00000048252.4
Bcat1

branched chain aminotransferase 1, cytosolic

chr2_+_29060239 0.107 ENSMUST00000100237.3
Ttf1
transcription termination factor, RNA polymerase I
chr1_+_63176818 0.093 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr10_+_36974558 0.092 ENSMUST00000105510.1
Hdac2
histone deacetylase 2
chr11_+_3963970 0.087 ENSMUST00000020705.4
ENSMUST00000109985.1
Pes1

pescadillo homolog 1, containing BRCT domain (zebrafish)

chr9_-_78443204 0.031 ENSMUST00000070742.7
ENSMUST00000034898.7
Mb21d1

Mab-21 domain containing 1

chr9_+_46012822 0.011 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 50.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
2.7 8.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166)
2.3 6.8 GO:0021759 globus pallidus development(GO:0021759)
0.9 2.8 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.8 2.5 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.7 4.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.6 8.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.6 1.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.6 4.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.6 4.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.5 2.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.4 1.3 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.4 2.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 1.2 GO:0015744 succinate transport(GO:0015744)
0.3 3.0 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.3 4.2 GO:1990403 embryonic brain development(GO:1990403)
0.3 3.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 1.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 2.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.6 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 0.5 GO:0060066 oviduct development(GO:0060066)
0.2 0.7 GO:1903416 response to glycoside(GO:1903416)
0.2 0.5 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 6.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:1903334 positive regulation of protein folding(GO:1903334)
0.1 0.8 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 2.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 1.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.9 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 3.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 4.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.6 GO:0006906 vesicle fusion(GO:0006906)
0.1 6.5 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.1 1.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 1.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.4 GO:0000059 protein import into nucleus, docking(GO:0000059)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.4 GO:0032366 intracellular sterol transport(GO:0032366)
0.0 0.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.9 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 1.9 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 2.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 3.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 3.6 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.5 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 8.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 4.2 GO:0005657 replication fork(GO:0005657)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 6.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.8 GO:0005903 brush border(GO:0005903)
0.0 6.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 40.7 GO:0005829 cytosol(GO:0005829)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 50.1 GO:0001784 phosphotyrosine binding(GO:0001784)
1.8 8.9 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
1.4 4.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.6 1.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6 6.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 2.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 1.2 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.3 2.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.3 1.3 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.2 1.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 4.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 0.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 8.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.5 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.1 2.8 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 4.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.7 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116) steroid hormone binding(GO:1990239)
0.1 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 4.0 GO:0005096 GTPase activator activity(GO:0005096)