Motif ID: Hey2

Z-value: 0.713


Transcription factors associated with Hey2:

Gene SymbolEntrez IDGene Name
Hey2 ENSMUSG00000019789.8 Hey2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hey2mm10_v2_chr10_-_30842765_30842801-0.491.0e-02Click!


Activity profile for motif Hey2.

activity profile for motif Hey2


Sorted Z-values histogram for motif Hey2

Sorted Z-values for motif Hey2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hey2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_120348513 2.311 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr5_+_141241490 2.219 ENSMUST00000085774.4
Sdk1
sidekick homolog 1 (chicken)
chr11_+_120721452 2.193 ENSMUST00000018156.5
Rac3
RAS-related C3 botulinum substrate 3
chr6_-_88875035 2.140 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr11_+_120721543 2.130 ENSMUST00000142229.1
Rac3
RAS-related C3 botulinum substrate 3
chr8_-_70700070 2.093 ENSMUST00000116172.1
Gm11175
predicted gene 11175
chr16_-_18621366 2.003 ENSMUST00000051160.2
Gp1bb
glycoprotein Ib, beta polypeptide
chr18_-_61911783 1.997 ENSMUST00000049378.8
ENSMUST00000166783.1
Ablim3

actin binding LIM protein family, member 3

chr13_-_14523178 1.932 ENSMUST00000110516.2
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr1_+_120340569 1.880 ENSMUST00000037286.8
C1ql2
complement component 1, q subcomponent-like 2
chr19_+_6418731 1.773 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
Nrxn2


neurexin II


chr2_-_168741898 1.693 ENSMUST00000109176.1
ENSMUST00000178504.1
Atp9a

ATPase, class II, type 9A

chr6_+_54816906 1.660 ENSMUST00000079869.6
Znrf2
zinc and ring finger 2
chr11_-_120348475 1.659 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr4_-_126753372 1.419 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr4_+_134468320 1.367 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
Stmn1


stathmin 1


chr11_+_101155884 1.262 ENSMUST00000043654.9
Tubg2
tubulin, gamma 2
chr4_+_85205120 1.212 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr2_-_85196697 1.204 ENSMUST00000099930.2
ENSMUST00000111601.1
Lrrc55

leucine rich repeat containing 55

chr2_-_168742100 1.177 ENSMUST00000109177.1
Atp9a
ATPase, class II, type 9A
chr3_-_88503187 1.132 ENSMUST00000120377.1
Lmna
lamin A
chr3_-_88503331 1.127 ENSMUST00000029699.6
Lmna
lamin A
chr4_+_129058133 1.119 ENSMUST00000030584.4
ENSMUST00000168461.1
ENSMUST00000152565.1
Rnf19b


ring finger protein 19B


chr7_-_25658726 1.112 ENSMUST00000071329.6
Bckdha
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr9_-_114933811 1.094 ENSMUST00000084853.3
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr9_-_114933929 1.088 ENSMUST00000146623.1
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr5_+_35757875 1.064 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
Ablim2



actin-binding LIM protein 2



chr11_+_116532441 1.050 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1



sphingosine kinase 1



chr13_-_25270076 1.037 ENSMUST00000057866.6
Nrsn1
neurensin 1
chr1_+_23762003 1.035 ENSMUST00000140583.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr11_+_120348678 0.996 ENSMUST00000143813.1
0610009L18Rik
RIKEN cDNA 0610009L18 gene
chr9_+_21165714 0.996 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr6_-_88874597 0.971 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2


podocalyxin-like 2


chr7_+_30169861 0.968 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr4_-_107683576 0.965 ENSMUST00000131776.1
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr11_-_120041774 0.952 ENSMUST00000103019.1
Aatk
apoptosis-associated tyrosine kinase
chr7_+_44384604 0.941 ENSMUST00000130707.1
ENSMUST00000130844.1
Syt3

synaptotagmin III

chr2_+_140395446 0.900 ENSMUST00000110061.1
Macrod2
MACRO domain containing 2
chr5_-_139484420 0.897 ENSMUST00000150992.1
Zfand2a
zinc finger, AN1-type domain 2A
chr5_-_121385599 0.887 ENSMUST00000146185.1
ENSMUST00000042312.7
Trafd1

TRAF type zinc finger domain containing 1

chr12_+_86678685 0.862 ENSMUST00000021681.3
Vash1
vasohibin 1
chr1_+_152766540 0.858 ENSMUST00000077755.5
ENSMUST00000097536.4
Arpc5

actin related protein 2/3 complex, subunit 5

chr11_+_103966716 0.858 ENSMUST00000057921.3
ENSMUST00000063347.5
Arf2

ADP-ribosylation factor 2

chr1_-_22805994 0.851 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr4_+_129985098 0.844 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2

brain-specific angiogenesis inhibitor 2

chr4_-_11966368 0.832 ENSMUST00000056050.4
ENSMUST00000108299.1
ENSMUST00000108297.2
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr4_+_33924632 0.805 ENSMUST00000057188.6
Cnr1
cannabinoid receptor 1 (brain)
chr8_+_85060055 0.797 ENSMUST00000095220.3
Fbxw9
F-box and WD-40 domain protein 9
chr5_-_138996087 0.784 ENSMUST00000110897.1
Pdgfa
platelet derived growth factor, alpha
chr9_-_53610329 0.769 ENSMUST00000034547.5
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr1_-_21961942 0.769 ENSMUST00000115300.1
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr2_-_114013619 0.768 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr4_+_104367549 0.748 ENSMUST00000106830.2
Dab1
disabled 1
chr16_-_22657165 0.738 ENSMUST00000089925.3
Dgkg
diacylglycerol kinase, gamma
chr14_-_121797670 0.706 ENSMUST00000100299.3
Dock9
dedicator of cytokinesis 9
chr8_+_65618009 0.695 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
March1


membrane-associated ring finger (C3HC4) 1


chr11_-_77489666 0.692 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr4_+_129984833 0.691 ENSMUST00000120204.1
Bai2
brain-specific angiogenesis inhibitor 2
chr2_+_24949747 0.689 ENSMUST00000028350.3
Zmynd19
zinc finger, MYND domain containing 19
chr10_+_17723220 0.681 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_+_182763961 0.673 ENSMUST00000153348.1
Susd4
sushi domain containing 4
chr2_+_128967383 0.662 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr5_+_111733924 0.659 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr4_+_155993143 0.655 ENSMUST00000097734.4
Sdf4
stromal cell derived factor 4
chr15_+_101174096 0.647 ENSMUST00000000544.9
Acvr1b
activin A receptor, type 1B
chr7_+_28693032 0.637 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27

F-box protein 27

chr13_-_68999518 0.626 ENSMUST00000022013.7
Adcy2
adenylate cyclase 2
chr9_+_22156838 0.612 ENSMUST00000123680.1
Pigyl
phosphatidylinositol glycan anchor biosynthesis, class Y-like
chr7_-_66427469 0.597 ENSMUST00000015278.7
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr13_+_58807884 0.595 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr2_-_180104463 0.585 ENSMUST00000056480.3
Hrh3
histamine receptor H3
chr17_+_25016343 0.583 ENSMUST00000024983.5
Ift140
intraflagellar transport 140
chr14_-_31128924 0.580 ENSMUST00000064032.4
ENSMUST00000049732.5
ENSMUST00000090205.3
Smim4


small itegral membrane protein 4


chr11_-_120348091 0.578 ENSMUST00000106215.4
Actg1
actin, gamma, cytoplasmic 1
chr11_-_115001880 0.574 ENSMUST00000092464.3
AF251705
cDNA sequence AF251705
chr16_+_33829624 0.557 ENSMUST00000115028.3
Itgb5
integrin beta 5
chr5_+_146948640 0.553 ENSMUST00000146511.1
ENSMUST00000132102.1
Gtf3a

general transcription factor III A

chr5_+_135168382 0.532 ENSMUST00000111187.3
ENSMUST00000111188.1
Bcl7b

B cell CLL/lymphoma 7B

chr9_+_103112072 0.529 ENSMUST00000035155.6
Rab6b
RAB6B, member RAS oncogene family
chr16_-_4624984 0.519 ENSMUST00000014445.6
Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr17_+_25016068 0.512 ENSMUST00000137386.1
Ift140
intraflagellar transport 140
chr7_-_27166413 0.506 ENSMUST00000108382.1
Egln2
EGL nine homolog 2 (C. elegans)
chr9_+_22156903 0.497 ENSMUST00000148088.1
Pigyl
phosphatidylinositol glycan anchor biosynthesis, class Y-like
chr1_+_23761749 0.486 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr15_+_52040107 0.484 ENSMUST00000090025.4
Aard
alanine and arginine rich domain containing protein
chr4_+_126753770 0.481 ENSMUST00000102607.3
ENSMUST00000047431.4
ENSMUST00000132660.1
AU040320


expressed sequence AU040320


chr17_-_47611449 0.461 ENSMUST00000024783.8
Bysl
bystin-like
chr14_-_33447142 0.455 ENSMUST00000111944.3
ENSMUST00000022504.5
ENSMUST00000111945.2
Mapk8


mitogen-activated protein kinase 8


chr5_-_24842579 0.444 ENSMUST00000030787.8
Rheb
Ras homolog enriched in brain
chr5_-_36398090 0.440 ENSMUST00000037370.7
ENSMUST00000070720.6
Sorcs2

sortilin-related VPS10 domain containing receptor 2

chr17_-_83631892 0.439 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr2_-_130424242 0.438 ENSMUST00000089581.4
Pced1a
PC-esterase domain containing 1A
chr11_+_115420059 0.416 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr4_+_148591482 0.413 ENSMUST00000006611.8
Srm
spermidine synthase
chr11_+_62248977 0.402 ENSMUST00000018644.2
Adora2b
adenosine A2b receptor
chr3_+_105452326 0.388 ENSMUST00000098761.3
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr14_+_45219993 0.387 ENSMUST00000146150.1
Gpr137c
G protein-coupled receptor 137C
chr8_+_87472838 0.377 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr10_-_112928974 0.373 ENSMUST00000099276.2
Atxn7l3b
ataxin 7-like 3B
chr11_+_113619318 0.363 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr12_+_4133394 0.344 ENSMUST00000152065.1
ENSMUST00000127756.1
Adcy3

adenylate cyclase 3

chr4_+_129513581 0.343 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr7_+_80261202 0.340 ENSMUST00000117989.1
Ngrn
neugrin, neurite outgrowth associated
chr5_+_135168283 0.333 ENSMUST00000031692.5
Bcl7b
B cell CLL/lymphoma 7B
chr3_-_9833617 0.323 ENSMUST00000108384.2
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr16_+_92058270 0.322 ENSMUST00000047429.8
ENSMUST00000113975.2
Mrps6
Slc5a3
mitochondrial ribosomal protein S6
solute carrier family 5 (inositol transporters), member 3
chr17_-_45686120 0.320 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr14_+_66297029 0.317 ENSMUST00000022623.6
ENSMUST00000121006.1
Trim35

tripartite motif-containing 35

chr10_+_80141457 0.313 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr3_-_9833653 0.313 ENSMUST00000161949.1
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr19_+_22139028 0.312 ENSMUST00000099569.2
ENSMUST00000087576.4
ENSMUST00000074770.5
Trpm3


transient receptor potential cation channel, subfamily M, member 3


chr5_-_25100624 0.298 ENSMUST00000030784.7
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr7_+_35119285 0.298 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr8_+_119394866 0.289 ENSMUST00000098367.4
Mlycd
malonyl-CoA decarboxylase
chr7_-_90457167 0.285 ENSMUST00000032844.5
Tmem126a
transmembrane protein 126A
chr11_-_106388066 0.283 ENSMUST00000106813.2
ENSMUST00000141146.1
Icam2

intercellular adhesion molecule 2

chr1_+_60409612 0.277 ENSMUST00000052332.8
Abi2
abl-interactor 2
chr1_-_16519284 0.277 ENSMUST00000162751.1
ENSMUST00000027052.6
ENSMUST00000149320.2
Stau2


staufen (RNA binding protein) homolog 2 (Drosophila)


chr7_-_30729505 0.276 ENSMUST00000006478.8
Tmem147
transmembrane protein 147
chr5_+_33018816 0.267 ENSMUST00000019109.7
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr1_+_119526125 0.262 ENSMUST00000183952.1
TMEM185B
Transmembrane protein 185B
chr8_-_94012558 0.257 ENSMUST00000053766.6
Amfr
autocrine motility factor receptor
chr17_-_31512253 0.252 ENSMUST00000166626.1
Wdr4
WD repeat domain 4
chr10_+_80142358 0.252 ENSMUST00000105366.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr10_-_11080956 0.242 ENSMUST00000105560.1
Grm1
glutamate receptor, metabotropic 1
chr8_+_87473116 0.237 ENSMUST00000182650.1
ENSMUST00000182758.1
ENSMUST00000181898.1
Gm2694


predicted gene 2694


chr4_+_138304723 0.229 ENSMUST00000030538.4
Ddost
dolichyl-di-phosphooligosaccharide-protein glycotransferase
chr11_+_74830920 0.229 ENSMUST00000000291.2
Mnt
max binding protein
chr7_-_44892358 0.216 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr1_+_36511867 0.213 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr19_-_5729618 0.207 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
Fam89b


family with sequence similarity 89, member B


chr6_-_88518760 0.204 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr15_-_76477269 0.201 ENSMUST00000023217.9
Bop1
block of proliferation 1
chr3_-_95315086 0.195 ENSMUST00000098867.3
Gm10691
predicted gene 10691
chr1_+_92906959 0.189 ENSMUST00000060913.6
Dusp28
dual specificity phosphatase 28
chr16_+_94085226 0.187 ENSMUST00000072182.7
Sim2
single-minded homolog 2 (Drosophila)
chr7_+_27486910 0.182 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr17_+_47611570 0.180 ENSMUST00000024778.2
Med20
mediator complex subunit 20
chr11_+_115420138 0.174 ENSMUST00000106533.1
ENSMUST00000123345.1
Kctd2

potassium channel tetramerisation domain containing 2

chr8_+_71568866 0.174 ENSMUST00000034267.4
Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
chrX_+_69360294 0.173 ENSMUST00000033532.6
Aff2
AF4/FMR2 family, member 2
chr8_+_87472805 0.169 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
Gm2694


predicted gene 2694


chr2_+_167503089 0.159 ENSMUST00000078050.6
Rnf114
ring finger protein 114
chr7_+_141447645 0.154 ENSMUST00000106004.1
ENSMUST00000106003.1
Rplp2

ribosomal protein, large P2

chr19_-_55099417 0.142 ENSMUST00000061856.5
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr10_+_80142295 0.141 ENSMUST00000003156.8
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr17_-_34122311 0.119 ENSMUST00000025193.6
Brd2
bromodomain containing 2
chr2_+_153345809 0.116 ENSMUST00000109790.1
Asxl1
additional sex combs like 1
chr17_-_27728889 0.109 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
Spdef



SAM pointed domain containing ets transcription factor



chr12_-_75735729 0.105 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr15_-_79328201 0.105 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
Pla2g6



phospholipase A2, group VI



chr4_-_141538562 0.103 ENSMUST00000105786.2
Spen
SPEN homolog, transcriptional regulator (Drosophila)
chr11_-_100939357 0.093 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr7_+_97696634 0.092 ENSMUST00000026506.4
Clns1a
chloride channel, nucleotide-sensitive, 1A
chr18_-_68300194 0.090 ENSMUST00000152193.1
Fam210a
family with sequence similarity 210, member A
chr1_-_127677923 0.076 ENSMUST00000160616.1
Tmem163
transmembrane protein 163
chr4_-_24851079 0.074 ENSMUST00000084781.5
ENSMUST00000108218.3
Klhl32

kelch-like 32

chr18_+_68300351 0.063 ENSMUST00000009679.4
ENSMUST00000131075.1
ENSMUST00000025427.7
ENSMUST00000139111.1
Rnmt



RNA (guanine-7-) methyltransferase



chr1_+_21218575 0.060 ENSMUST00000027065.5
ENSMUST00000027064.7
Tmem14a

transmembrane protein 14A

chr6_+_125192154 0.058 ENSMUST00000032485.5
Mrpl51
mitochondrial ribosomal protein L51
chr9_-_56418023 0.051 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr4_+_128654686 0.045 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr11_+_60104971 0.035 ENSMUST00000064190.6
Rai1
retinoic acid induced 1
chr1_-_16519201 0.029 ENSMUST00000159558.1
ENSMUST00000054668.6
ENSMUST00000162627.1
ENSMUST00000162007.1
ENSMUST00000128957.2
ENSMUST00000115359.3
ENSMUST00000151888.1
Stau2






staufen (RNA binding protein) homolog 2 (Drosophila)






chr7_+_101321703 0.022 ENSMUST00000174291.1
ENSMUST00000167888.2
ENSMUST00000172662.1
ENSMUST00000173270.1
ENSMUST00000174083.1
Stard10




START domain containing 10




chr11_+_60105079 0.022 ENSMUST00000132012.1
Rai1
retinoic acid induced 1
chr11_+_102189620 0.018 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr8_-_111933761 0.017 ENSMUST00000034429.7
Tmem231
transmembrane protein 231
chr10_+_69212676 0.014 ENSMUST00000167384.1
Rhobtb1
Rho-related BTB domain containing 1
chr18_-_36454487 0.012 ENSMUST00000025204.5
Pfdn1
prefoldin 1
chr11_-_97700327 0.012 ENSMUST00000018681.7
Pcgf2
polycomb group ring finger 2
chr17_-_34121944 0.008 ENSMUST00000151986.1
Brd2
bromodomain containing 2
chr9_+_119894876 0.006 ENSMUST00000036561.6
Wdr48
WD repeat domain 48

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.6 2.3 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.5 4.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.3 0.8 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 0.7 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 0.7 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.2 0.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.9 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 3.1 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 0.4 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.2 0.8 GO:0031622 positive regulation of fever generation(GO:0031622)
0.2 0.6 GO:0060166 olfactory pit development(GO:0060166)
0.2 0.6 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 0.7 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.2 0.7 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.2 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.5 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 4.5 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.3 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 1.0 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956) diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.9 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 0.2 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.3 GO:0008355 olfactory learning(GO:0008355)
0.1 2.2 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 3.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 1.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.9 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.1 0.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.4 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 1.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.2 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.0 0.4 GO:0030432 peristalsis(GO:0030432)
0.0 0.3 GO:0015791 polyol transport(GO:0015791)
0.0 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0071435 potassium ion export(GO:0071435)
0.0 0.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.3 GO:0021554 optic nerve development(GO:0021554)
0.0 0.7 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 1.0 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 1.4 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.9 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.3 GO:0006706 steroid catabolic process(GO:0006706)
0.0 1.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 2.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.6 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 1.6 GO:0007596 blood coagulation(GO:0007596)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 1.1 GO:0044194 cytolytic granule(GO:0044194)
0.3 2.3 GO:0005638 lamin filament(GO:0005638)
0.3 1.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.2 0.6 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.2 8.9 GO:0031941 filamentous actin(GO:0031941)
0.1 1.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.5 GO:0031314 mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.5 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 2.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 3.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.2 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 2.1 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.8 GO:0030118 clathrin coat(GO:0030118)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0030133 transport vesicle(GO:0030133)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.9 GO:0000502 proteasome complex(GO:0000502)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 2.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 1.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 1.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.6 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 2.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.8 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.3 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 2.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 5.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.2 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 4.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 3.0 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)