Motif ID: Hey2
Z-value: 0.713
Transcription factors associated with Hey2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hey2 | ENSMUSG00000019789.8 | Hey2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hey2 | mm10_v2_chr10_-_30842765_30842801 | -0.49 | 1.0e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
0.6 | 2.3 | GO:1904177 | regulation of adipose tissue development(GO:1904177) |
0.5 | 4.3 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
0.3 | 0.8 | GO:0010512 | negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) |
0.2 | 0.7 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.2 | 0.9 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.2 | 0.7 | GO:0070625 | zymogen granule exocytosis(GO:0070625) |
0.2 | 0.9 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
0.2 | 0.9 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.2 | 3.1 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.2 | 0.4 | GO:0002678 | positive regulation of chronic inflammatory response(GO:0002678) |
0.2 | 0.8 | GO:0031622 | positive regulation of fever generation(GO:0031622) |
0.2 | 0.6 | GO:0060166 | olfactory pit development(GO:0060166) |
0.2 | 0.6 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.2 | 0.7 | GO:0061428 | embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
0.2 | 0.7 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) |
0.2 | 0.6 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
0.1 | 1.1 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.1 | 0.5 | GO:2000017 | positive regulation of determination of dorsal identity(GO:2000017) |
0.1 | 4.5 | GO:0045214 | sarcomere organization(GO:0045214) |
0.1 | 0.9 | GO:0051639 | actin filament network formation(GO:0051639) |
0.1 | 0.1 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.1 | 0.4 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
0.1 | 0.6 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.1 | 0.3 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
0.1 | 1.0 | GO:0001956 | positive regulation of neurotransmitter secretion(GO:0001956) diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.1 | 0.9 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
0.1 | 0.2 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
0.1 | 1.0 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
0.1 | 0.3 | GO:0008355 | olfactory learning(GO:0008355) |
0.1 | 2.2 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
0.1 | 3.4 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.1 | 1.1 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.1 | 1.5 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
0.1 | 0.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.1 | 1.4 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.1 | 1.1 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.1 | 0.2 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.1 | 0.5 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.1 | 0.9 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
0.1 | 0.6 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
0.1 | 0.4 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
0.0 | 1.3 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.0 | 1.2 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
0.0 | 0.3 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.0 | 0.5 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.0 | 0.3 | GO:0000050 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
0.0 | 0.4 | GO:0030432 | peristalsis(GO:0030432) |
0.0 | 0.3 | GO:0015791 | polyol transport(GO:0015791) |
0.0 | 1.0 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
0.0 | 0.4 | GO:0071435 | potassium ion export(GO:0071435) |
0.0 | 0.7 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.0 | 0.3 | GO:0021554 | optic nerve development(GO:0021554) |
0.0 | 0.7 | GO:0042297 | vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598) |
0.0 | 0.6 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.0 | 1.0 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 0.1 | GO:1904685 | positive regulation of metalloendopeptidase activity(GO:1904685) |
0.0 | 0.3 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.0 | 0.1 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.0 | 0.1 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.0 | 0.1 | GO:0060480 | lung goblet cell differentiation(GO:0060480) |
0.0 | 0.2 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.0 | 1.4 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
0.0 | 0.9 | GO:0045824 | negative regulation of innate immune response(GO:0045824) |
0.0 | 0.3 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 1.8 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
0.0 | 0.3 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.0 | 0.7 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.5 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.0 | 0.2 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.3 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.0 | 2.0 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
0.0 | 0.6 | GO:0050868 | negative regulation of T cell activation(GO:0050868) |
0.0 | 1.6 | GO:0007596 | blood coagulation(GO:0007596) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.4 | 1.1 | GO:0044194 | cytolytic granule(GO:0044194) |
0.3 | 2.3 | GO:0005638 | lamin filament(GO:0005638) |
0.3 | 1.1 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.2 | 0.6 | GO:0048179 | activin receptor complex(GO:0048179) |
0.2 | 0.6 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
0.2 | 8.9 | GO:0031941 | filamentous actin(GO:0031941) |
0.1 | 1.1 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 0.7 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 0.3 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
0.1 | 0.5 | GO:0031314 | mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.1 | 1.1 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.1 | 0.9 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.1 | 0.5 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.1 | 1.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 0.8 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 2.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.3 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
0.0 | 0.3 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 3.8 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 0.7 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.5 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.6 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 1.6 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.3 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 0.2 | GO:0070545 | PeBoW complex(GO:0070545) |
0.0 | 1.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.1 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
0.0 | 0.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 1.2 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
0.0 | 2.1 | GO:0070382 | exocytic vesicle(GO:0070382) |
0.0 | 0.8 | GO:0030118 | clathrin coat(GO:0030118) |
0.0 | 0.8 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 1.0 | GO:0030133 | transport vesicle(GO:0030133) |
0.0 | 0.3 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.9 | GO:0000502 | proteasome complex(GO:0000502) |
0.0 | 0.2 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 2.6 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.2 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
0.3 | 1.0 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.3 | 1.5 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
0.2 | 0.8 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.2 | 0.6 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
0.1 | 2.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 0.8 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
0.1 | 0.4 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.1 | 0.6 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.1 | 0.6 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.1 | 0.6 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.1 | 1.1 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
0.1 | 0.7 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 0.3 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.1 | 2.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.4 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.1 | 5.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.1 | 0.9 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
0.1 | 0.7 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.1 | 0.6 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.2 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) |
0.1 | 0.4 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
0.1 | 0.3 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.1 | 0.5 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 0.5 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.1 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 0.3 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.1 | 4.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.7 | GO:0042287 | MHC protein binding(GO:0042287) |
0.0 | 1.2 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.0 | 1.8 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.3 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
0.0 | 0.9 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.0 | 0.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 1.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 1.0 | GO:0030552 | cAMP binding(GO:0030552) |
0.0 | 0.3 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.0 | 0.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.2 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
0.0 | 0.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.3 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) |
0.0 | 0.2 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
0.0 | 0.2 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
0.0 | 0.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.2 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 0.2 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 3.0 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |