Motif ID: Hic1

Z-value: 1.267


Transcription factors associated with Hic1:

Gene SymbolEntrez IDGene Name
Hic1 ENSMUSG00000043099.4 Hic1



Activity profile for motif Hic1.

activity profile for motif Hic1


Sorted Z-values histogram for motif Hic1

Sorted Z-values for motif Hic1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84800024 5.530 ENSMUST00000126806.1
ENSMUST00000076715.6
 Nfix

nuclear factor I/X

chr8_-_84800344 3.724 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chr11_-_6065538 3.458 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr12_+_73997749 2.964 ENSMUST00000110451.2
 Syt16
synaptotagmin XVI
chr4_-_139092958 2.820 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr8_+_70493156 2.787 ENSMUST00000008032.7
 Crlf1
cytokine receptor-like factor 1
chr6_-_32588192 2.729 ENSMUST00000115096.2
 Plxna4
plexin A4
chr7_+_130936172 2.694 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr11_-_32222233 2.687 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr13_+_54949388 2.659 ENSMUST00000026994.7
ENSMUST00000109994.2
 Unc5a

unc-5 homolog A (C. elegans)

chr5_-_62766153 2.657 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_46991842 2.575 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr3_-_88000350 2.556 ENSMUST00000090971.5
 Bcan
brevican
chr9_+_45430293 2.518 ENSMUST00000034592.8
 Dscaml1
Down syndrome cell adhesion molecule like 1
chr5_-_146585239 2.410 ENSMUST00000036211.6
 Gpr12
G-protein coupled receptor 12
chr14_-_30353468 2.353 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr11_+_63131512 2.164 ENSMUST00000018361.3
 Pmp22
peripheral myelin protein 22
chr7_+_113207465 2.116 ENSMUST00000047321.7
 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr5_+_141241490 2.097 ENSMUST00000085774.4
 Sdk1
sidekick homolog 1 (chicken)
chr10_+_79716588 2.093 ENSMUST00000099513.1
ENSMUST00000020581.2
 Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 418 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 11.3 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683)
0.3 5.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.8 5.4 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.2 5.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.9 3.8 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.5 3.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.2 3.5 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.4 3.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 3.2 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.0 3.1 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 3.1 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 3.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 3.0 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.7 2.7 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.4 2.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 2.6 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.4 2.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 2.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.5 GO:0032060 bleb assembly(GO:0032060)
0.1 2.5 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 161 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 33.4 GO:0016021 integral component of membrane(GO:0016021)
0.1 14.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 9.5 GO:0000139 Golgi membrane(GO:0000139)
0.2 8.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 6.4 GO:0051233 spindle midzone(GO:0051233)
0.1 6.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 5.0 GO:0032590 dendrite membrane(GO:0032590)
0.0 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 3.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 3.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.9 2.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 2.7 GO:0031091 platelet alpha granule(GO:0031091)
0.5 2.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 2.4 GO:0033391 chromatoid body(GO:0033391)
0.0 2.4 GO:0043679 axon terminus(GO:0043679)
0.2 2.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 2.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 2.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 266 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.2 GO:0005096 GTPase activator activity(GO:0005096)
0.2 5.0 GO:0043274 phospholipase binding(GO:0043274)
0.8 4.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 4.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.8 3.9 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 3.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.8 GO:0030332 cyclin binding(GO:0030332)
0.6 3.7 GO:0005042 netrin receptor activity(GO:0005042)
1.2 3.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.9 3.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 3.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.6 3.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 3.2 GO:0050811 GABA receptor binding(GO:0050811)
0.4 3.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 3.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 3.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 3.0 GO:0003924 GTPase activity(GO:0003924)
0.9 2.8 GO:0016015 morphogen activity(GO:0016015)
0.1 2.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.8 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)