Motif ID: Hif1a

Z-value: 0.939


Transcription factors associated with Hif1a:

Gene SymbolEntrez IDGene Name
Hif1a ENSMUSG00000021109.7 Hif1a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hif1amm10_v2_chr12_+_73907904_73907970-0.262.0e-01Click!


Activity profile for motif Hif1a.

activity profile for motif Hif1a


Sorted Z-values histogram for motif Hif1a

Sorted Z-values for motif Hif1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hif1a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_46845832 3.960 ENSMUST00000048209.9
ENSMUST00000092621.4
Ldha

lactate dehydrogenase A

chr7_-_30973367 2.666 ENSMUST00000108116.3
Lsr
lipolysis stimulated lipoprotein receptor
chr7_-_30973399 2.663 ENSMUST00000098553.4
ENSMUST00000147431.1
Lsr

lipolysis stimulated lipoprotein receptor

chr19_+_25610533 2.540 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr1_-_17097839 2.429 ENSMUST00000038382.4
Jph1
junctophilin 1
chr18_+_74442500 2.054 ENSMUST00000074157.6
Myo5b
myosin VB
chr2_+_27886416 1.937 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr16_+_70313949 1.918 ENSMUST00000163832.1
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr2_+_71873224 1.894 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr3_-_95882193 1.888 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr16_+_70314087 1.788 ENSMUST00000023393.8
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chrX_-_93832106 1.775 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr10_-_78009737 1.759 ENSMUST00000020522.8
Pfkl
phosphofructokinase, liver, B-type
chr16_+_70314119 1.708 ENSMUST00000170464.2
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr4_-_55532453 1.683 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr16_+_70314057 1.643 ENSMUST00000171132.1
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr14_-_20181773 1.629 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr6_-_125165707 1.566 ENSMUST00000118875.1
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr2_+_168081004 1.520 ENSMUST00000052125.6
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr17_+_28769307 1.516 ENSMUST00000004986.6
Mapk13
mitogen-activated protein kinase 13
chr8_+_106893616 1.483 ENSMUST00000047629.5
Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr1_-_153549697 1.470 ENSMUST00000041874.7
Npl
N-acetylneuraminate pyruvate lyase
chr6_-_125165576 1.418 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr1_+_74771886 1.262 ENSMUST00000006716.6
Wnt6
wingless-related MMTV integration site 6
chr11_-_102819663 1.105 ENSMUST00000092567.4
Gjc1
gap junction protein, gamma 1
chr4_+_150236816 1.082 ENSMUST00000080926.6
Eno1
enolase 1, alpha non-neuron
chr3_-_95882232 1.065 ENSMUST00000161866.1
Gm129
predicted gene 129
chr11_+_54100924 1.058 ENSMUST00000093107.5
ENSMUST00000019050.5
ENSMUST00000174616.1
ENSMUST00000129499.1
ENSMUST00000126840.1
P4ha2




procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide




chr11_-_72411695 1.053 ENSMUST00000108500.1
ENSMUST00000050226.6
Smtnl2

smoothelin-like 2

chr5_-_149051604 1.040 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr13_+_38345716 1.036 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr14_-_45318556 1.021 ENSMUST00000022378.7
Ero1l
ERO1-like (S. cerevisiae)
chr14_-_31019055 1.009 ENSMUST00000037739.6
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr8_-_106893581 1.007 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
Chtf8



CTF8, chromosome transmission fidelity factor 8



chr18_+_35553401 1.006 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr9_+_107569112 1.003 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr4_+_116877376 1.000 ENSMUST00000044823.3
Zswim5
zinc finger SWIM-type containing 5
chr5_+_129020069 0.994 ENSMUST00000031383.7
ENSMUST00000111343.1
Ran

RAN, member RAS oncogene family

chr11_-_89302545 0.992 ENSMUST00000061728.3
Nog
noggin
chr4_+_150237211 0.988 ENSMUST00000133839.1
Eno1
enolase 1, alpha non-neuron
chr4_-_129600642 0.967 ENSMUST00000102593.4
Eif3i
eukaryotic translation initiation factor 3, subunit I
chr1_+_172481788 0.957 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr14_+_21052574 0.950 ENSMUST00000045376.9
Adk
adenosine kinase
chr4_+_150236685 0.855 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr7_-_138909492 0.834 ENSMUST00000106112.1
Bnip3
BCL2/adenovirus E1B interacting protein 3
chr8_-_106893515 0.822 ENSMUST00000176090.1
Chtf8
CTF8, chromosome transmission fidelity factor 8
chr8_+_83997613 0.796 ENSMUST00000095228.3
Samd1
sterile alpha motif domain containing 1
chr5_-_149051300 0.795 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr4_+_152325831 0.774 ENSMUST00000103191.4
ENSMUST00000139685.1
Rpl22

ribosomal protein L22

chr4_-_129600586 0.768 ENSMUST00000135055.1
Eif3i
eukaryotic translation initiation factor 3, subunit I
chr4_-_11386757 0.729 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr13_-_29984219 0.728 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr5_+_110653444 0.724 ENSMUST00000031478.5
Ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr5_-_135251209 0.710 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr6_-_29212240 0.703 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr2_+_27515157 0.690 ENSMUST00000113952.3
Wdr5
WD repeat domain 5
chr5_+_33658123 0.690 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr10_-_127180579 0.681 ENSMUST00000095270.2
Slc26a10
solute carrier family 26, member 10
chr17_-_45573253 0.675 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr8_-_124949165 0.673 ENSMUST00000034469.5
Egln1
EGL nine homolog 1 (C. elegans)
chr6_+_125131869 0.668 ENSMUST00000044200.8
Nop2
NOP2 nucleolar protein
chr10_+_128238034 0.655 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr17_-_56626872 0.649 ENSMUST00000047226.8
Lonp1
lon peptidase 1, mitochondrial
chr14_-_7174533 0.637 ENSMUST00000172431.1
Gm3512
predicted gene 3512
chr6_+_49073795 0.632 ENSMUST00000128616.1
ENSMUST00000031839.6
ENSMUST00000114500.1
Malsu1


mitochondrial assembly of ribosomal large subunit 1


chr6_+_88724828 0.621 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr15_-_36608959 0.618 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr15_-_75909319 0.616 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr6_+_88724462 0.611 ENSMUST00000113582.1
Mgll
monoglyceride lipase
chr1_+_78310295 0.606 ENSMUST00000036172.8
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr2_+_156840966 0.604 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr13_+_90923122 0.597 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr12_+_32820304 0.594 ENSMUST00000020886.7
Nampt
nicotinamide phosphoribosyltransferase
chr15_-_75909289 0.582 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr10_-_13193096 0.578 ENSMUST00000019950.4
Ltv1
LTV1 homolog (S. cerevisiae)
chr1_-_161251153 0.572 ENSMUST00000051925.4
ENSMUST00000071718.5
Prdx6

peroxiredoxin 6

chr5_-_135064063 0.565 ENSMUST00000111205.1
ENSMUST00000141309.1
Wbscr22

Williams Beuren syndrome chromosome region 22

chr1_+_172482199 0.548 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr14_+_5501674 0.532 ENSMUST00000181562.1
Gm3488
predicted gene, 3488
chr1_+_55088132 0.531 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr8_-_116993459 0.525 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr1_-_75180349 0.517 ENSMUST00000027396.8
Abcb6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr14_-_31830402 0.505 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr9_-_96364299 0.502 ENSMUST00000034983.5
Atp1b3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr14_-_19585135 0.499 ENSMUST00000170694.1
Gm2237
predicted gene 2237
chr3_-_9004472 0.498 ENSMUST00000091355.5
ENSMUST00000134788.1
Tpd52

tumor protein D52

chr11_+_60537978 0.497 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr16_+_20498817 0.496 ENSMUST00000003320.6
Eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr11_+_121259983 0.485 ENSMUST00000106113.1
Foxk2
forkhead box K2
chr14_+_33319703 0.483 ENSMUST00000111955.1
Arhgap22
Rho GTPase activating protein 22
chr15_+_102203639 0.479 ENSMUST00000118729.1
ENSMUST00000119168.1
ENSMUST00000141465.1
ENSMUST00000139960.1
Zfp740



zinc finger protein 740



chr16_+_20673517 0.472 ENSMUST00000115460.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr6_+_88724489 0.471 ENSMUST00000113581.1
Mgll
monoglyceride lipase
chr7_-_105736781 0.466 ENSMUST00000033179.6
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr7_+_3704025 0.464 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr19_-_31765027 0.455 ENSMUST00000065067.6
Prkg1
protein kinase, cGMP-dependent, type I
chr3_-_101110278 0.451 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr2_+_31887262 0.451 ENSMUST00000138325.1
ENSMUST00000028187.6
Lamc3

laminin gamma 3

chr18_+_52465676 0.450 ENSMUST00000025406.7
Srfbp1
serum response factor binding protein 1
chr2_-_181459364 0.449 ENSMUST00000155535.1
ENSMUST00000029106.6
ENSMUST00000087409.3
Zbtb46


zinc finger and BTB domain containing 46


chr14_+_4334763 0.432 ENSMUST00000165466.1
2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr2_-_130582554 0.429 ENSMUST00000046001.6
Avp
arginine vasopressin
chr4_-_139352538 0.427 ENSMUST00000102503.3
Mrto4
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr6_-_72958465 0.425 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr1_-_38129618 0.423 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr9_-_110654161 0.419 ENSMUST00000133191.1
ENSMUST00000167320.1
Nbeal2

neurobeachin-like 2

chr7_+_98703091 0.389 ENSMUST00000033009.9
Prkrir
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr8_-_45999860 0.388 ENSMUST00000053558.9
Ankrd37
ankyrin repeat domain 37
chr15_-_75909543 0.386 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr14_-_89898466 0.354 ENSMUST00000081204.4
Gm10110
predicted gene 10110
chr16_+_20673264 0.353 ENSMUST00000154950.1
ENSMUST00000115461.1
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chr4_-_133967953 0.346 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr1_+_63176818 0.345 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr4_-_62519885 0.344 ENSMUST00000107444.1
ENSMUST00000030090.3
Alad

aminolevulinate, delta-, dehydratase

chr4_-_21685782 0.336 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr3_-_9004686 0.335 ENSMUST00000120143.1
Tpd52
tumor protein D52
chr6_+_108828633 0.329 ENSMUST00000089162.3
Edem1
ER degradation enhancer, mannosidase alpha-like 1
chr11_+_97315716 0.329 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr1_+_120602405 0.326 ENSMUST00000079721.7
En1
engrailed 1
chr4_-_139352298 0.323 ENSMUST00000030513.6
ENSMUST00000155257.1
Mrto4

MRT4, mRNA turnover 4, homolog (S. cerevisiae)

chr11_-_115491796 0.322 ENSMUST00000106530.1
ENSMUST00000021082.6
Nt5c

5',3'-nucleotidase, cytosolic

chr5_+_108694222 0.302 ENSMUST00000013633.8
ENSMUST00000112560.3
Fgfrl1

fibroblast growth factor receptor-like 1

chr10_+_80226644 0.300 ENSMUST00000130260.1
Mum1
melanoma associated antigen (mutated) 1
chr7_+_89980749 0.290 ENSMUST00000181784.1
Gm26529
predicted gene, 26529
chr14_-_6287250 0.290 ENSMUST00000170104.2
Gm3411
predicted gene 3411
chr6_+_85451488 0.280 ENSMUST00000032078.6
Cct7
chaperonin containing Tcp1, subunit 7 (eta)
chr7_+_129257027 0.274 ENSMUST00000094018.4
Ppapdc1a
phosphatidic acid phosphatase type 2 domain containing 1A
chrX_+_159414572 0.272 ENSMUST00000112471.2
Map7d2
MAP7 domain containing 2
chr11_-_104442232 0.271 ENSMUST00000106977.1
ENSMUST00000106972.1
Kansl1

KAT8 regulatory NSL complex subunit 1

chr2_-_121140371 0.270 ENSMUST00000099486.2
Lcmt2
leucine carboxyl methyltransferase 2
chr14_+_3652030 0.259 ENSMUST00000167430.1
Gm3020
predicted gene 3020
chr2_-_163419508 0.254 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chr17_+_46681038 0.252 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chr1_+_172148015 0.251 ENSMUST00000074144.5
Dcaf8
DDB1 and CUL4 associated factor 8
chr5_-_33657889 0.246 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr2_+_155517948 0.241 ENSMUST00000029135.8
ENSMUST00000065973.2
ENSMUST00000103142.5
Acss2


acyl-CoA synthetase short-chain family member 2


chr14_+_3572023 0.239 ENSMUST00000178728.1
Gm3005
predicted gene 3005
chr17_-_46752170 0.239 ENSMUST00000121671.1
ENSMUST00000059844.6
Cnpy3

canopy 3 homolog (zebrafish)

chr19_+_45006475 0.239 ENSMUST00000026227.2
Peo1
progressive external ophthalmoplegia 1 (human)
chr2_+_162931520 0.238 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr16_-_24393588 0.238 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr6_-_85451248 0.234 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chrX_+_143518671 0.231 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chrX_+_143518576 0.229 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr15_-_31453564 0.225 ENSMUST00000110408.1
Ropn1l
ropporin 1-like
chr13_+_118714678 0.224 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr14_-_18893376 0.219 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr16_-_20241304 0.212 ENSMUST00000040880.7
Map6d1
MAP6 domain containing 1
chr6_+_29272488 0.208 ENSMUST00000115289.1
ENSMUST00000054445.8
Hilpda

hypoxia inducible lipid droplet associated

chr5_+_52190650 0.205 ENSMUST00000180601.1
9230114K14Rik
RIKEN cDNA 9230114K14 gene
chr1_+_9545397 0.189 ENSMUST00000072079.7
Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr7_-_44986313 0.188 ENSMUST00000045325.6
ENSMUST00000085387.4
ENSMUST00000107840.1
ENSMUST00000107843.3
ENSMUST00000107842.3
Prmt1




protein arginine N-methyltransferase 1




chr7_-_45466894 0.186 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr10_+_43479140 0.181 ENSMUST00000167488.1
ENSMUST00000040147.7
Bend3

BEN domain containing 3

chr2_+_128126030 0.174 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr9_+_106203108 0.172 ENSMUST00000024047.5
Twf2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr8_-_69974367 0.165 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr9_-_67760208 0.159 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr9_+_108347827 0.158 ENSMUST00000035237.6
Usp4
ubiquitin specific peptidase 4 (proto-oncogene)
chr14_+_3332627 0.153 ENSMUST00000177786.1
Gm2956
predicted gene 2956
chr4_+_131873608 0.140 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr1_-_55088024 0.139 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr14_-_21052420 0.139 ENSMUST00000154460.1
Ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr4_+_129600670 0.137 ENSMUST00000102591.3
ENSMUST00000181579.1
ENSMUST00000173758.1
Tmem234


transmembrane protein 234


chrX_+_135993820 0.135 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr6_+_88724667 0.132 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr19_-_45006385 0.120 ENSMUST00000097715.2
Mrpl43
mitochondrial ribosomal protein L43
chr14_+_4182576 0.116 ENSMUST00000164512.1
Gm2974
predicted gene 2974
chr7_-_126502094 0.114 ENSMUST00000179818.1
Atxn2l
ataxin 2-like
chr13_+_55635002 0.109 ENSMUST00000172272.1
ENSMUST00000099479.3
Ddx46

DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

chr18_+_64340225 0.100 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr4_+_11191354 0.099 ENSMUST00000170901.1
Ccne2
cyclin E2
chr9_+_107587711 0.090 ENSMUST00000010192.5
Ifrd2
interferon-related developmental regulator 2
chr17_-_27133902 0.089 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr14_+_4726775 0.085 ENSMUST00000165619.1
Gm3252
predicted gene 3252
chr11_-_120348475 0.083 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr19_+_18713225 0.083 ENSMUST00000055792.7
D030056L22Rik
RIKEN cDNA D030056L22 gene
chr5_-_144965793 0.080 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1


SMAD specific E3 ubiquitin protein ligase 1


chr5_+_100039990 0.079 ENSMUST00000169390.1
ENSMUST00000031268.6
Enoph1

enolase-phosphatase 1

chr1_+_16665189 0.076 ENSMUST00000177501.1
ENSMUST00000065373.5
Tmem70

transmembrane protein 70

chr15_-_93336800 0.072 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr7_+_141228766 0.071 ENSMUST00000106027.2
Phrf1
PHD and ring finger domains 1
chr15_+_101174096 0.071 ENSMUST00000000544.9
Acvr1b
activin A receptor, type 1B
chr11_+_78178651 0.070 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr11_+_84880308 0.066 ENSMUST00000020837.6
Myo19
myosin XIX
chr10_-_85102487 0.062 ENSMUST00000059383.6
Fhl4
four and a half LIM domains 4
chr10_-_79766872 0.051 ENSMUST00000047203.8
Rnf126
ring finger protein 126
chr17_-_27133620 0.039 ENSMUST00000118613.1
Uqcc2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr2_-_26237368 0.032 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr6_+_88724412 0.027 ENSMUST00000113585.2
Mgll
monoglyceride lipase
chr2_+_6322621 0.025 ENSMUST00000114937.1
Usp6nl
USP6 N-terminal like
chr18_+_65581704 0.025 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr11_+_117115133 0.024 ENSMUST00000021177.8
Sec14l1
SEC14-like 1 (S. cerevisiae)
chr10_+_80755196 0.021 ENSMUST00000105336.2
Dot1l
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr14_-_70443442 0.019 ENSMUST00000000793.5
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr11_-_77489666 0.018 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr11_+_87127052 0.018 ENSMUST00000041282.6
Trim37
tripartite motif-containing 37
chr9_+_21165714 0.012 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr12_+_105032638 0.011 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr16_+_18248961 0.010 ENSMUST00000100099.3
Trmt2a
TRM2 tRNA methyltransferase 2A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.9 3.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.8 4.0 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.7 3.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.7 0.7 GO:0033122 regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.6 1.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 1.8 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.6 1.7 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.5 2.1 GO:0032439 endosome localization(GO:0032439)
0.4 1.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.3 0.9 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.3 0.8 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) response to cobalt ion(GO:0032025)
0.3 1.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 1.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2 2.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 1.8 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.5 GO:2000224 testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224)
0.2 0.7 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.2 0.6 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.2 1.0 GO:0042117 hyaluronan catabolic process(GO:0030214) monocyte activation(GO:0042117)
0.2 1.0 GO:1902570 protein localization to nucleolus(GO:1902570)
0.2 1.8 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 0.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 2.1 GO:0019471 4-hydroxyproline metabolic process(GO:0019471)
0.2 1.0 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.2 1.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of cellular pH reduction(GO:0032847) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.4 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.5 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 0.5 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.2 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 6.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.3 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 0.4 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.2 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.2 GO:0006083 acetate metabolic process(GO:0006083)
0.1 1.3 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.1 0.4 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.6 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.5 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.1 1.6 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.7 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.6 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.7 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.9 GO:0014002 astrocyte development(GO:0014002)
0.0 2.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.6 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.5 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 2.6 GO:0006413 translational initiation(GO:0006413)
0.0 3.0 GO:0071229 cellular response to acid chemical(GO:0071229)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.6 GO:0010470 regulation of gastrulation(GO:0010470)
0.0 1.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0070131 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) positive regulation of mitochondrial translation(GO:0070131) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.1 GO:0007601 visual perception(GO:0007601)
0.0 0.7 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.2 GO:0006364 rRNA processing(GO:0006364)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.3 GO:0061689 tricellular tight junction(GO:0061689)
0.6 1.9 GO:0005588 collagen type V trimer(GO:0005588)
0.6 1.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.5 1.5 GO:0034455 t-UTP complex(GO:0034455)
0.5 2.4 GO:0030314 junctional membrane complex(GO:0030314)
0.4 1.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 3.0 GO:0097452 GAIT complex(GO:0097452)
0.3 2.1 GO:0045179 apical cortex(GO:0045179)
0.3 1.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.3 1.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 4.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 1.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 1.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.9 GO:0043196 varicosity(GO:0043196)
0.1 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.7 GO:0048188 MLL3/4 complex(GO:0044666) Set1C/COMPASS complex(GO:0048188)
0.1 1.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 1.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 2.5 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
1.0 3.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
1.0 4.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.9 3.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 1.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.4 1.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 1.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 2.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 5.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.3 1.0 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 1.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 1.0 GO:0070883 importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883)
0.2 1.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 1.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 0.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 1.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.0 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.1 2.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.6 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 1.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.7 GO:0002135 CTP binding(GO:0002135)
0.1 0.4 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 1.0 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.1 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.4 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.1 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.9 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 2.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 2.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.9 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 2.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.0 GO:0019955 cytokine binding(GO:0019955)
0.0 0.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.6 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.8 GO:0051082 unfolded protein binding(GO:0051082)