Motif ID: Hivep1

Z-value: 0.448


Transcription factors associated with Hivep1:

Gene SymbolEntrez IDGene Name
Hivep1 ENSMUSG00000021366.7 Hivep1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hivep1mm10_v2_chr13_+_42052015_420520720.145.1e-01Click!


Activity profile for motif Hivep1.

activity profile for motif Hivep1


Sorted Z-values histogram for motif Hivep1

Sorted Z-values for motif Hivep1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hivep1

PNG image of the network

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Top targets:


Showing 1 to 20 of 130 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_79164477 1.806 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr3_-_88000350 1.771 ENSMUST00000090971.5
Bcan
brevican
chr3_+_117575268 1.552 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr6_-_136171722 1.294 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr14_+_80000292 1.209 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr10_-_27616895 1.085 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr7_+_99535439 1.041 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr7_+_99535652 1.031 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr17_-_83631892 1.013 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr7_-_4546567 0.992 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr2_+_23321246 0.887 ENSMUST00000102945.1
Nxph2
neurexophilin 2
chr2_-_104257400 0.873 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr18_+_37496997 0.834 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr7_+_27653906 0.766 ENSMUST00000008088.7
Ttc9b
tetratricopeptide repeat domain 9B
chr11_+_78188737 0.690 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr3_-_53657339 0.676 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr18_+_37484955 0.660 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr2_-_5063996 0.655 ENSMUST00000114996.1
Optn
optineurin
chr13_+_42866247 0.652 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr5_+_137030275 0.647 ENSMUST00000041543.8
Vgf
VGF nerve growth factor inducible

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.8 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.8 GO:0021766 hippocampus development(GO:0021766)
0.1 1.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049) detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.3 1.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 1.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 1.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2 1.1 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 1.1 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 1.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 0.6 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.2 0.6 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.6 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.6 GO:0043084 penile erection(GO:0043084)
0.0 0.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.6 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0031143 pseudopodium(GO:0031143)
0.2 1.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 1.7 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.2 GO:0042581 specific granule(GO:0042581)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0000802 transverse filament(GO:0000802)
0.0 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 1.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 1.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 1.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)